Refining Adjuvant Therapy for Endometrial Cancer: New Standards and Perspectives

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Randomized Phase II Trial of Carboplatin–Paclitaxel Compared with Carboplatin–Paclitaxel–Trastuzumab in Advanced (Stage III–IV) or Recurrent Uterine Serous Carcinomas that Overexpress Her2/Neu (NCT01367002): Updated Overall Survival Analysis

(2020) Amanda N. Fader et al.   CLINICAL CANCER RESEARCH

Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy

(2020) Alicia León-Castillo et al.   JOURNAL OF CLINICAL ONCOLOGY

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

(2020) Anne Sophie V M van den Heerik et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma

(2020) Nicole Concin et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Phase III Trial: Adjuvant Pelvic Radiation Therapy Versus Vaginal Brachytherapy Plus Paclitaxel/Carboplatin in High-Intermediate and High-Risk Early Stage Endometrial Cancer

(2019) Marcus E. Randall et al.   JOURNAL OF CLINICAL ONCOLOGY

Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial

(2019) Stephanie M de Boer et al.   LANCET ONCOLOGY

Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer

(2019) Daniela Matei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Incorporation of molecular characteristics into endometrial cancer management

(2019) Lisa Vermij et al.   HISTOPATHOLOGY

Clinicopathological and molecular characterisation of ‘multiple‐classifier’ endometrial carcinomas

(2019) Alicia León‐Castillo et al.   JOURNAL OF PATHOLOGY

Interpretation of somatic POLE mutations in endometrial carcinoma

(2019) Alicia León‐Castillo et al.   JOURNAL OF PATHOLOGY

Molecular Classification of Grade 3 Endometrioid Endometrial Cancers Identifies Distinct Prognostic Subgroups

(2018) Tjalling Bosse et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The role of adjuvant therapy in stage IA serous and clear cell uterine cancer: A multi-institutional pooled analysis

(2018) X. Melody Qu et al.   GYNECOLOGIC ONCOLOGY

International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project

(2018) Kathleen R. Cho et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial

(2018) Stephanie M de Boer et al.   LANCET ONCOLOGY

Combined external beam radiotherapy and vaginal brachytherapy versus vaginal brachytherapy in stage I, intermediate- and high-risk cases of endometrium carcinoma

(2018) Sunil R.A. et al.   Journal of Contemporary Brachytherapy

Improved survival with adjuvant brachytherapy in stage IA endometrial cancer of unfavorable histology

(2018) Ashwin Shinde et al.   GYNECOLOGIC ONCOLOGY

Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapy

(2018) B. G. Wortman et al.   BRITISH JOURNAL OF CANCER

Increased Incidence of Endometrial Cancer Following the Women's Health Initiative: An Assessment of Risk Factors

(2018) Ginger D. Constantine et al.   JOURNAL OF WOMENS HEALTH

Utility of radiation therapy for early-stage uterine papillary serous carcinoma

(2017) Stephanie Cham et al.   GYNECOLOGIC ONCOLOGY

Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts

(2016) Ellen Stelloo et al.   CLINICAL CANCER RESEARCH

A clinically applicable molecular-based classification for endometrial cancers

(2015) A Talhouk et al.   BRITISH JOURNAL OF CANCER

Survival of women with cancers of breast and genital organs in Europe 1999–2007: Results of the EUROCARE-5 study

(2015) Milena Sant et al.   EUROPEAN JOURNAL OF CANCER

Omitting Adjuvant Radiotherapy in Endometrial Cancer Increases the Rate of Locoregional Recurrences but Has no Effect on Long-Term Survival

(2013) Gitte Ørtoft et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

The Role of Vaginal Brachytherapy in the Treatment of Surgical Stage I Papillary Serous or Clear Cell Endometrial Cancer

(2012) Brandon M. Barney et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

External Pelvic and Vaginal Irradiation Versus Vaginal Irradiation Alone as Postoperative Therapy in Medium-Risk Endometrial Carcinoma—A Prospective Randomized Study

(2011) Bengt Sorbe et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Sequential adjuvant chemotherapy and radiotherapy in endometrial cancer–Results from two randomised studies

(2010) Thomas Hogberg et al.   EUROPEAN JOURNAL OF CANCER

Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial

(2010) RA Nout et al.   LANCET

Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis

(2008)   LANCET

Randomized phase III trial of pelvic radiotherapy versus cisplatin-based combined chemotherapy in patients with intermediate- and high-risk endometrial cancer: A Japanese Gynecologic Oncology Group study

(2007) Nobuyuki Susumu et al.   GYNECOLOGIC ONCOLOGY