TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors

Recent trends in the development of Toll-like receptor 7/8-targeting therapeutics

(2021) Xuan Huang et al.   Expert Opinion on Drug Discovery

Structural and functional understanding of the toll‐like receptors

(2021) Jinta Asami et al.   PROTEIN SCIENCE

HIV infection suppresses TLR3 activation‐mediated antiviral immunity in microglia and macrophages

(2020) Hang Liu et al.   IMMUNOLOGY

Agonist and antagonist ligands of toll-like receptors 7 and 8: Ingenious tools for therapeutic purposes

(2020) Cindy Patinote et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pattern Recognition Receptor Ligands as an Emerging Therapeutic Agent for Latent HIV-1 Infection

(2020) Shokichi Takahama et al.   Frontiers in Cellular and Infection Microbiology

Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19

(2020) Athina Angelopoulou et al.   ENVIRONMENTAL RESEARCH

Detection of Viral Infections by Innate Immunity

(2020) Michael Carty et al.   BIOCHEMICAL PHARMACOLOGY

Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice

(2019) Eunice E. To et al.   Scientific Reports

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART

(2019) Nadine Bachmann et al.   Nature Communications

The HIV Reservoir in Monocytes and Macrophages

(2019) Michelle E. Wong et al.   Frontiers in Immunology

Interleukin-10 polymorphisms and susceptibility to ARV associated hepatotoxicity

(2019) HariOm Singh et al.   MICROBIAL PATHOGENESIS

The Role of Macrophages in HIV-1 Persistence and Pathogenesis

(2019) Zita Kruize et al.   Frontiers in Microbiology

Intercellular communication for innate immunity

(2017) Tan A. Nguyen et al.   MOLECULAR IMMUNOLOGY

The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome

(2017) Carlene Petes et al.   Frontiers in Immunology

TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells

(2016) Rujuta A. Bam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction

(2016) Toshana L. Foster et al.   Cell Host & Microbe

TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes

(2016) Henning Hofmann et al.   Retrovirology

Activation of NF- B via Endosomal Toll-Like Receptor 7 (TLR7) or TLR9 Suppresses Murine Herpesvirus 68 Reactivation

(2014) F. Haas et al.   JOURNAL OF VIROLOGY

Gardiquimod: A Toll-Like Receptor-7 Agonist That Inhibits HIV Type 1 Infection of Human Macrophages and Activated T Cells

(2013) Maarten Buitendijk et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Immune activation of human brain microvascular endothelial cells inhibits HIV replication in macrophages

(2013) J. Li et al.   BLOOD

Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2-/-  C-/- mice in vivo

(2011) L. Zhang et al.   BLOOD

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

(2011) A. N. Harman et al.   BLOOD

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1β

(2010) G. HERBEIN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages

(2010) Yu Zhou et al.   IMMUNOLOGY

Suppressor of Cytokine Signaling 3 Inhibits Antiviral IFN-  Signaling To Enhance HIV-1 Replication in Macrophages

(2010) L. N. Akhtar et al.   JOURNAL OF IMMUNOLOGY

A Succession of Mechanisms Stimulate Efficient Reconstituted HIV-1 Minus Strand Strong Stop DNA Transfer†

(2009) Min Song et al.   BIOCHEMISTRY

Imiquimod 5% cream for external genital or perianal warts in human immunodeficiency virus-positive patients treated with highly active antiretroviral therapy: an open-label, noncomparative study

(2009) P. Saiag et al.   BRITISH JOURNAL OF DERMATOLOGY

Human Immunodeficiency Virus Type 1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells

(2009) B. P. Doehle et al.   JOURNAL OF VIROLOGY

Imiquimod Leads to a Decrease of Human Papillomavirus DNA and to a Sustained Clearance of Anal Intraepithelial Neoplasia in HIV-Infected Men

(2008) Alexander Kreuter et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Strand transfer events during HIV-1 reverse transcription

(2008) Vandana Purohit Basu et al.   VIRUS RESEARCH

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

(2007) Atsushi Okumura et al.   VIROLOGY