Dietary Interventions Reduce Traditional and Novel Cardiovascular Risk Markers by Altering the Gut Microbiome and Their Metabolites

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

(2021) Francesco Asnicar et al.   NATURE MEDICINE

Ceramide Scores Predict Cardiovascular Risk in the Community

(2021) Vlad C. Vasile et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Precision Microbiome Modulation with Discrete Dietary Fiber Structures Directs Short-Chain Fatty Acid Production

(2020) Edward C. Deehan et al.   Cell Host & Microbe

Effects of Omega-3 Fatty Acid Supplements on Arrhythmias

(2020) Sarah Parish et al.   CIRCULATION

Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

(2020) Tarini Shankar Ghosh et al.   GUT

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

(2020) David M. Kaye et al.   CIRCULATION

Gut Microbiota and Cardiovascular Disease

(2020) Marco Witkowski et al.   CIRCULATION RESEARCH

GlycA, a novel marker for low grade inflammation, reflects gut microbiome diversity and is more accurate than high sensitive CRP in reflecting metabolomic profile

(2020) Kati Mokkala et al.   Metabolomics

Associations between Diet, the Gut Microbiome, and Short-Chain Fatty Acid Production among Older Caribbean Latino Adults

(2020) Ana Maldonado-Contreras et al.   Journal of the Academy of Nutrition and Dietetics

Omega-3 index and blood pressure responses to eating foods naturally enriched with omega-3 polyunsaturated fatty acids: a randomized controlled trial

(2020) Alice V. Stanton et al.   Scientific Reports

The prebiotic effects of omega-3 fatty acid supplementation: A six-week randomised intervention trial

(2020) Amrita Vijay et al.   Gut Microbes

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

Carbohydrate quality and human health: a series of systematic reviews and meta-analyses

(2019) Andrew Reynolds et al.   LANCET

Alterations in the gut microbiome and metabolism with coronary artery disease severity

(2019) Honghong Liu et al.   Microbiome

TwinsUK: The UK Adult Twin Registry Update

(2019) Serena Verdi et al.   Twin Research and Human Genetics

REDUCE-IT USA: Results from the 3,146 Patients Randomized in the United States

(2019) Deepak L. Bhatt et al.   CIRCULATION

Lower gut microbiome diversity and higher abundance of proinflammatory genus Collinsella are associated with biopsy-proven nonalcoholic steatohepatitis

(2019) Stuart Astbury et al.   Gut Microbes

Plasma Ceramides

(2018) Jeffrey W. Meeusen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure

(2018) Seungbum Kim et al.   CLINICAL SCIENCE

Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study

(2018) Rozenn N. Lemaitre et al.   DIABETES

Ceramide Remodeling and Risk of Cardiovascular Events and Mortality

(2018) Linda R. Peterson et al.   Journal of the American Heart Association

A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

(2017) Henry Watson et al.   GUT

GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk

(2017) Margery A. Connelly et al.   Journal of Translational Medicine

Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women

(2017) Cristina Menni et al.   Scientific Reports

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

(2016) Melanie Schirmer et al.   CELL

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive MiceClinical Perspective

(2016) Francine Z. Marques et al.   CIRCULATION

Executive Summary: Heart Disease and Stroke Statistics—2016 Update

(2016) Dariush Mozaffarian et al.   CIRCULATION

Glycosylation Signatures of Inflammation Identify Cardiovascular Risk

(2016) Patrick R. Lawler et al.   CIRCULATION RESEARCH

Cardiovascular disease in Europe: epidemiological update 2016

(2016) Nick Townsend et al.   EUROPEAN HEART JOURNAL

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

(2016) Reijo Laaksonen et al.   EUROPEAN HEART JOURNAL

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

(2016) Mingming Sun et al.   JOURNAL OF GASTROENTEROLOGY

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics

(2015) Pasi Soininen et al.   Circulation-Cardiovascular Genetics

Statin action favors normalization of the plasma lipidome in the atherogenic mixed dyslipidemia of MetS: potential relevance to statin-associated dysglycemia

(2015) Peter J. Meikle et al.   JOURNAL OF LIPID RESEARCH

Modulation of sphingolipid metabolism with calorie restriction enhances insulin action in skeletal muscle

(2015) Diana N. Obanda et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics

(2015) Pasi Soininen et al.   Circulation-Cardiovascular Genetics

GlycA, a Pro-Inflammatory Glycoprotein Biomarker, and Incident Cardiovascular Disease: Relationship with C-Reactive Protein and Renal Function

(2015) Eke G. Gruppen et al.   PLoS One

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Effect of Probiotic (VSL#3) and Omega-3 on Lipid Profile, Insulin Sensitivity, Inflammatory Markers, and Gut Colonization in Overweight Adults: A Randomized, Controlled Trial

(2014) Hemalatha Rajkumar et al.   MEDIATORS OF INFLAMMATION

A Novel Protein Glycan Biomarker and Future Cardiovascular Disease Events

(2014) Akintunde O. Akinkuolie et al.   Journal of the American Heart Association

Gut Microbiota-Derived Short-Chain Fatty Acids, T Cells, and Inflammation

(2014) Chang H. Kim et al.   Immune Network

Immunity, atherosclerosis and cardiovascular disease

(2013) Johan Frostegård   BMC Medicine

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

(2013) Jennifer L. Pluznick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The UK Adult Twin Registry (TwinsUK Resource)

(2012) Alireza Moayyeri et al.   Twin Research and Human Genetics

Gastric Bypass Surgery Reduces Plasma Ceramide Subspecies and Improves Insulin Sensitivity in Severely Obese Patients

(2011) Hazel Huang et al.   Obesity