Sustainable synthesis of enantiopure fluorolactam derivatives by a selective direct fluorination – amidase strategy

Fluorine gas for life science syntheses: green metrics to assess selective direct fluorination for the synthesis of 2-fluoromalonate esters

(2015) Antal Harsanyi et al.   GREEN CHEMISTRY

GREEN MOTION: a new and easy to use green chemistry metric from laboratories to industry

(2015) T. V. Tony Phan et al.   GREEN CHEMISTRY

Towards a holistic approach to metrics for the 21st century pharmaceutical industry

(2015) C. Robert McElroy et al.   GREEN CHEMISTRY

Asymmetric Fluorination Approach to the Scalable Synthesis of a SYK Inhibitor

(2015) Neil R. Curtis et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Fluorotetrahydroquinolines from Diethyl 2-Fluoromalonate Ester

(2014) Craig A. Fisher et al.   CHIMIA

Beyond C, H, O, and N! Analysis of the Elemental Composition of U.S. FDA Approved Drug Architectures

(2014) Brandon R. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Electrophilic Fluorocyclization with Carbon Nucleophiles

(2013) Jamie R. Wolstenhulme et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery

(2013) Elizabeth A. Ilardi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chiral Anion Phase-Transfer Catalysis Applied to the Direct Enantioselective Fluorinative Dearomatization of Phenols

(2013) Robert J. Phipps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel synthesis of various orthogonally protected Cα-methyllysine analogues and biological evaluation of a Vapreotide analogue containing (S)-α-methyllysine

(2013) Souvik Banerjee et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective synthesis of α-halo-α-alkylmalonates via phase-transfer catalytic α-alkylation

(2013) Suckchang Hong et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Fluorination of Enamides: Access to α-Fluoroimines Using an Anionic Chiral Phase-Transfer Catalyst

(2012) Robert J. Phipps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pseudomonas stutzeri lipase: a useful biocatalyst for aminolysis reactions

(2011) S. van Pelt et al.   GREEN CHEMISTRY

Immunosuppressive but Non-LasR-Inducing Analogues of thePseudomonas aeruginosaQuorum-Sensing MoleculeN-(3-Oxododecanoyl)-l-homoserine Lactone

(2011) Gopal P. Jadhav et al.   JOURNAL OF MEDICINAL CHEMISTRY

Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes

(2011) Concepcion Jimenez-Gonzalez et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Electrophilic Fluorination Using an Anionic Chiral Phase-Transfer Catalyst

(2011) V. Rauniyar et al.   SCIENCE

Recent Advances in Catalytic Enantioselective Fluorination Reactions

(2010) Sylvain Lectard et al.   ADVANCED SYNTHESIS & CATALYSIS

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Asymmetric Fluorination Comes of Age

(2007) Vincent A. Brunet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Desymmetrization-like Catalytic Enantioselective Fluorination of Malonates and Its Application to Pharmaceutically Attractive Molecules

(2007) Dhande Sudhakar Reddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS

A new rationale of reaction metrics for green chemistry. Mathematical expression of the environmental impact factor of chemical processes

(2007) Jacques Augé   GREEN CHEMISTRY