Binge-like Alcohol Exposure in Adolescence: Behavioural, Neuroendocrine and Molecular Evidence of Abnormal Neuroplasticity… and Return

FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currents

(2021) Nitin Khandelwal et al.   MOLECULAR PSYCHIATRY

Cannabidiol as a Potential Treatment for Anxiety and Mood Disorders: Molecular Targets and Epigenetic Insights from Preclinical Research

(2021) Philippe A. Melas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cannabinoids, reward processing, and psychosis

(2021) Brandon Gunasekera et al.   PSYCHOPHARMACOLOGY

Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development

(2020) Ashley G. Anderson et al.   Cell Reports

Reward Circuitry and Motivational Deficits in Social Anxiety Disorder: What Can Be Learned From Mouse Models?

(2020) Corinne N. Carlton et al.   Frontiers in Neuroscience

In utero Δ9-tetrahydrocannabinol exposure confers vulnerability towards cognitive impairments and alcohol drinking in the adolescent offspring: Is there a role for neuropeptide Y?

(2020) Anna Brancato et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Effect of alcohol use on the adolescent brain and behavior

(2020) Briana Lees et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Molecular and neurocircuitry mechanisms of social avoidance

(2020) Anne-Kathrin Gellner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus

(2020) Melkamu Alemu Abame et al.   NEUROSCIENCE LETTERS

Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats

(2020) Martina Di Bartolomeo et al.   PHARMACOLOGICAL RESEARCH

Cannabidiol as a Novel Candidate Alcohol Use Disorder Pharmacotherapy: A Systematic Review

(2019) Jasmine Turna et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Gender differences in the effects of cannabidiol on ethanol binge drinking in mice

(2019) Adrián Viudez-Martínez et al.   ADDICTION BIOLOGY

Cannabidiol for the Reduction of Cue-Induced Craving and Anxiety in Drug-Abstinent Individuals With Heroin Use Disorder: A Double-Blind Randomized Placebo-Controlled Trial

(2019) Yasmin L. Hurd et al.   AMERICAN JOURNAL OF PSYCHIATRY

Coping with the forced swim stressor: Current state-of-the-art

(2019) Marc L. Molendijk et al.   BEHAVIOURAL BRAIN RESEARCH

A Motivational and Neuropeptidergic Hub: Anatomical and Functional Diversity within the Nucleus Accumbens Shell

(2019) Daniel C. Castro et al.   NEURON

Mechanisms of persistent neurobiological changes following adolescent alcohol exposure: NADIA Consortium findings

(2019) Fulton T. Crews et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Altered actin filament dynamics in the Drosophila mushroom bodies lead to fast acquisition of alcohol consumption preference

(2019) Andrew R. Butts et al.   JOURNAL OF NEUROSCIENCE

Adolescent neurodevelopment and substance use: Receptor expression and behavioral consequences

(2019) Hayley H.A. Thorpe et al.   PHARMACOLOGY & THERAPEUTICS

Affective Disturbances During Withdrawal from Chronic Intermittent Ethanol Inhalation in C57BL/6J and DBA/2J Male Mice

(2018) Harpreet Sidhu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Cannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal

(2018) Francisco Navarrete et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functional organization of postsynaptic glutamate receptors

(2018) Nicky Scheefhals et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The anxiolytic effects of cannabidiol in chronically stressed mice are mediated by the endocannabinoid system: Role of neurogenesis and dendritic remodeling

(2018) Manoela V. Fogaça et al.   NEUROPHARMACOLOGY

Pre-conceptional and Peri-Gestational Maternal Binge Alcohol Drinking Produces Inheritance of Mood Disturbances and Alcohol Vulnerability in the Adolescent Offspring

(2018) Anna Brancato et al.   Frontiers in Psychiatry

Dopamine restores limbic memory loss, dendritic spine structure and NMDAR-dependent LTD in the nucleus accumbens of alcohol-withdrawn rats

(2018) Carla Cannizzaro et al.   JOURNAL OF NEUROSCIENCE

Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress

(2018) Adrián Viudez-Martínez et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia

(2018) Tibor Stark et al.   NEUROPHARMACOLOGY

Neuronal and molecular effects of cannabidiol on the mesolimbic dopamine system: Implications for novel schizophrenia treatments

(2017) Justine Renard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders

(2017) Alline C. Campos et al.   Frontiers in Pharmacology

SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to drive dendritic morphogenesis

(2017) Daniel L. Rocca et al.   Scientific Reports

Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex—Possible involvement of 5-HT1A and CB1 receptors

(2016) A.G. Sartim et al.   BEHAVIOURAL BRAIN RESEARCH

Preclinical voluntary drinking models for alcohol abstinence-induced affective disturbances in mice

(2016) K. M. Holleran et al.   GENES BRAIN AND BEHAVIOR

Applicability of Commercially Available ELISA Kits for the Quantification of Faecal Immunoreactive Corticosterone Metabolites in Mice

(2016) KLAS S.P ABELSON et al.   IN VIVO

The First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens Dopamine D1 Receptor Neurons

(2016) J. T. Beckley et al.   JOURNAL OF NEUROSCIENCE

Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking

(2016) Katherine M Holleran et al.   NEUROPSYCHOPHARMACOLOGY

Anxiolytic effects of muscarinic acetylcholine receptors agonist oxotremorine in chronically stressed rats and related changes in BDNF and FGF2 levels in the hippocampus and prefrontal cortex

(2016) Valentina Di Liberto et al.   PSYCHOPHARMACOLOGY

Continuous and Intermittent Alcohol Free-Choice from Pre-gestational Time to Lactation: Focus on Drinking Trajectories and Maternal Behavior

(2016) Anna Brancato et al.   Frontiers in Behavioral Neuroscience

Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines

(2015) Joachim D. Uys et al.   ADDICTION BIOLOGY

Acetaldehyde self-administration by a two-bottle choice paradigm: Consequences on emotional reactivity, spatial learning, and memory

(2015) Fulvio Plescia et al.   ALCOHOL

Glutamate presynaptic vesicular transporter and postsynaptic receptor levels correlate with spatial memory status in aging rat models

(2015) Caroline Ménard et al.   NEUROBIOLOGY OF AGING

Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala

(2015) Kristen E. Pleil et al.   NEUROPHARMACOLOGY

Adolescent alcohol exposure: Are there separable vulnerable periods within adolescence?

(2015) Linda Patia Spear   PHYSIOLOGY & BEHAVIOR

Adolescent binge-like alcohol alters sensitivity to acute alcohol effects on dopamine release in the nucleus accumbens of adult rats

(2015) Tatiana A. Shnitko et al.   PSYCHOPHARMACOLOGY

Social defeat in adolescent mice increases vulnerability to alcohol consumption

(2014) Marta Rodriguez-Arias et al.   ADDICTION BIOLOGY

Chronic intermittent ethanol exposure during adolescence: Effects on social behavior and ethanol sensitivity in adulthood

(2014) Elena I. Varlinskaya et al.   ALCOHOL

Data calibration and reduction allows to visualize behavioural profiles of psychosocial influences in mice towards clinical domains

(2014) Dorota M. Badowska et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Involvement of Dopamine D2 Receptors in Addictive-Like Behaviour for Acetaldehyde

(2014) Anna Brancato et al.   PLoS One

Hampered long-term depression and thin spine loss in the nucleus accumbens of ethanol-dependent rats

(2014) S. Spiga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Acetaldehyde Intoxication and Withdrawal on NPY Expression: Focus on Endocannabinoidergic System Involvement

(2014) Fulvio Plescia et al.   Frontiers in Psychiatry

Depression-related behaviours displayed by female C57BL/6J mice during abstinence from chronic ethanol consumption are rescued by wheel-running

(2013) Terence Y. Pang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway

(2013) Jessica J Walsh et al.   NATURE NEUROSCIENCE

Addiction as a stress surfeit disorder

(2013) George F. Koob et al.   NEUROPHARMACOLOGY

Increased Extracellular Glutamate In the Nucleus Accumbens Promotes Excessive Ethanol Drinking in Ethanol Dependent Mice

(2013) William C Griffin III et al.   NEUROPSYCHOPHARMACOLOGY

Craving in Alcohol-Dependent Patients After Detoxification Is Related to Glutamatergic Dysfunction in the Nucleus Accumbens and the Anterior Cingulate Cortex

(2013) Jochen Bauer et al.   NEUROPSYCHOPHARMACOLOGY

Anxiolytic effects of the GABAA receptor partial agonist, L-838,417: Impact of age, test context familiarity, and stress

(2013) Melissa Morales et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Dopamine Signaling in reward-related behaviors

(2013) Ja-Hyun Baik   Frontiers in Neural Circuits

Acetaldehyde as a drug of abuse: insight into AM281 administration on operant-conflict paradigm in rats

(2013) Fulvio Plescia et al.   Frontiers in Behavioral Neuroscience

Extreme Binge Drinking Among 12th-Grade Students in the United States

(2013) Megan E. Patrick et al.   JAMA Pediatrics

Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease

(2012) Bin Tang et al.   HUMAN MOLECULAR GENETICS

Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults

(2012) James E. McCutcheon et al.   JOURNAL OF NEUROPHYSIOLOGY

Development of the social brain in adolescence

(2012) Sarah-Jayne Blakemore   JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

(2012) Julia C. Lemos et al.   NATURE

The Mysterious Motivational Functions of Mesolimbic Dopamine

(2012) John D. Salamone et al.   NEURON

Endocannabinoid system and mood disorders: Priming a target for new therapies

(2012) Vincenzo Micale et al.   PHARMACOLOGY & THERAPEUTICS

Altered fear learning across development in both mouse and human

(2012) S. S. Pattwell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Administration of cannabidiol and imipramine induces antidepressant-like effects in the forced swimming test and increases brain-derived neurotrophic factor levels in the rat amygdala.

(2011) Gislaine Z. Réus et al.   ACTA NEUROPSYCHIATRICA

Evaluation of chronic alcohol self-administration by a 3-bottle choice paradigm in adult male rats. Effects on behavioural reactivity, spatial learning and reference memory

(2011) Silvana Cacace et al.   BEHAVIOURAL BRAIN RESEARCH

Effect of alcohol consumption in prenatal life, childhood, and adolescence on child development

(2011) Francesca Foltran et al.   NUTRITION REVIEWS

Alcohol Dysregulates Corticotropin-Releasing-Hormone (CRH) Promoter Activity by Interfering with the Negative Glucocorticoid Response Element (nGRE)

(2011) Magdalena M. Przybycien-Szymanska et al.   PLoS One

Alcohol problems in young adults transitioning from adolescence to adulthood: The association with race and gender

(2010) Karen G. Chartier et al.   ADDICTIVE BEHAVIORS

Ethanol Modulates Corticotropin Releasing Hormone Release From the Rat Hypothalamus: Does Acetaldehyde Play a Role?

(2010) Carla Cannizzaro et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Age-related reduction in dopamine D1 receptors in the human brain: from late childhood to adulthood, a positron emission tomography study

(2010) A. Jucaite et al.   NEUROSCIENCE

Repeated restraint stress alters sensitivity to the social consequences of ethanol in adolescent and adult rats

(2010) Elena I. Varlinskaya et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Antidepressant-like effect of Δ9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

(2010) Abir T. El-Alfy et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Ethanol-Sensitive Brain Regions in Rat and Mouse: A Cartographic Review, Using Immediate Early Gene Expression

(2009) Catherine Vilpoux et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Binge-pattern alcohol exposure during puberty induces sexually dimorphic changes in genes regulating the HPA axis

(2009) Magdalena M. Przybycien-Szymanska et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains

(2009) F Josef van der Staay et al.   Behavioral and Brain Functions

Age matters

(2009) James Edgar McCutcheon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Modulation of effective connectivity during emotional processing by Δ9-tetrahydrocannabinol and cannabidiol

(2009) Paolo Fusar-Poli et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Stress-Induced Changes in Nucleus Accumbens Glutamate Synaptic Plasticity

(2009) Matthew R. Campioni et al.   JOURNAL OF NEUROPHYSIOLOGY

Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances

(2009) Y. Ren et al.   JOURNAL OF NEUROSCIENCE

Strain Differences in Alcohol-Induced Neurochemical Plasticity: A Role for Accumbens Glutamate in Alcohol Intake

(2008) Zuzana Kapasova et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Social interactions in adolescent and adult Sprague–Dawley rats: Impact of social deprivation and test context familiarity

(2008) E VARLINSKAYA   BEHAVIOURAL BRAIN RESEARCH

Effector Immediate-Early Gene Arc in the Amygdala Plays a Critical Role in Alcoholism

(2008) S. C. Pandey et al.   JOURNAL OF NEUROSCIENCE

Abstinence following Alcohol Drinking Produces Depression-Like Behavior and Reduced Hippocampal Neurogenesis in Mice

(2008) Jennie R Stevenson et al.   NEUROPSYCHOPHARMACOLOGY

A developmental neurobiological model of motivated behavior: Anatomy, connectivity and ontogeny of the triadic nodes

(2008) Monique Ernst et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Glutamatergic substrates of drug addiction and alcoholism

(2007) Justin T. Gass et al.   BIOCHEMICAL PHARMACOLOGY