Article
Biochemistry & Molecular Biology
Rebecca Swanson, Zully Contreras-Correa, Thu Dinh, Heath King, Darcie Sidelinger, Derris Burnett, Caleb Lemley
Summary: Melatonin rescues the effects of nutrient restriction on uterine blood flow and fetal body weight in a seasonal dependent manner within a bovine model. It has been found to regulate maternal and fetal amino acids and placental nutrient transporters.
Article
Environmental Sciences
Fei-Xiang Xu, Xu Chen, Heng Zhang, Yi-Jun Fan, Ya-Ping Song, Jin-Wei Lv, Ya-Li Xie, Yichao Huang, Dao-Zhen Chen, Hua Wang, De-Xiang Xu
Summary: Gestational arsenic exposure is associated with intrauterine growth restriction, and this restriction may be related to a reduction in folate content in maternal and umbilical plasma.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Midori Awazu
Summary: The early developmental environment affects health and disease risk in adulthood, particularly in relation to the structure and function of the kidneys. Low birth weight and preterm birth can result in structural changes in the kidneys, with low nephron number being a main alteration.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Developmental Biology
Mandy Busse, Stefanie Langwisch, Kerry Tedford, Klaus-Dieter Fischer, Ana Claudia Zenclussen
Summary: B cell participation in early embryo/fetal development and the underlying molecular pathways have been explored in this study. The study suggests that B cell-specific MyD88 and IL10 expression is crucial for appropriate embryo development, and IL10+8 cells play a role in regulating uterine blood flow during pregnancy. Furthermore, B cell-specific CD19, MyD88, and IL10 expression influences susceptibility towards preterm birth.
Review
Biochemistry & Molecular Biology
Giorgia Sebastiani, Elisabet Navarro-Tapia, Laura Almeida-Toledano, Mariona Serra-Delgado, Anna Lucia Paltrinieri, Oscar Garcia-Algar, Vicente Andreu-Fernandez
Summary: Hypoxia and oxidative stress are crucial for fetal development during pregnancy, but an imbalance in oxidative molecules can lead to complications. Antioxidants may be a promising tool for treating these complications.
Article
Microbiology
Yu Pi, Yujun Wu, Xiangyu Zhang, Dongdong Lu, Dandan Han, Jiangchao Zhao, Xiaojiao Zheng, Shiyi Zhang, Hao Ye, Shuai Lian, Yu Bai, Zhenyu Wang, Shiyu Tao, Dongjiao Ni, Xinhua Zou, Wei Jia, Guolong Zhang, Defa Li, Junjun Wang
Summary: In this study, the difference in fecal microbiome and bile acid (BA) profiles between low birth weight (LBW) and normal birth weight (NBW) piglets were investigated. Fecal microbiota transplantation confirmed the link between microbial BA metabolism and intestinal inflammation. The therapeutic potential of ursodeoxycholic acid (UDCA) was evaluated and it was found to alleviate intestinal inflammation through M2 macrophage polarization and suppression of inflammatory cytokines.
Article
Nutrition & Dietetics
Malgorzata Lewandowska
Summary: The study found that maternal pre-pregnancy obesity is associated with an increased risk of low birth weight, fetal growth restriction, and macrosomia in newborns. Additionally, the risk of macrosomia was three times higher for obese mothers, while the risk of low birth weight was 17 times higher, particularly in the subgroup of normal gestational weight gain. The risk profile showed that higher BMI values were associated with a higher risk of these outcomes, with specific threshold BMI values identified.
Article
Medicine, General & Internal
Wen Huang, Jin Zhou, Juanjuan Guo, Wen Hu, Guanghui Chen, Bin Li, Yajie Wen, Yimin Jiang, Kaili Fu, Huichang Bi, Yuanzhen Zhang, Hui Wang
Summary: Prenatal dexamethasone exposure can have lasting adverse effects on bile acid metabolism in offspring by affecting placental BA transporters and inducing imbalanced fetal-placental-maternal BA circulation, leading to increased levels of primary BAs in fetal serum.
Article
Multidisciplinary Sciences
Jennifer Ish, David Gimeno Ruiz de Porras, Elaine Symanski, Ferran Ballester, Maribel Casas, George L. Delclos, Monica Guxens, Jesus Ibarluzea, Carmen Iniguez, Loreto Santa-Marina, Michael D. Swartz, Kristina W. Whitworth
Summary: This study examines the associations between maternal occupational exposures and ultrasound-measured fetal growth. The results suggest limited evidence that occupational exposures may impact fetal growth, especially those related to endocrine disrupting chemicals.
Article
Endocrinology & Metabolism
Manuela Fernandez-Lopez, Jose Eliseo Blanco-Carnero, Juan Manuel Guardia-Baena, Catalina De Paco-Matallana, Aurora Aragon-Alonso, Antonio Miguel Hernandez-Martinez
Summary: Flexible treatment according to the measurement of fetal abdominal circumference in gestational diabetes mellitus is safe for both mother and fetus, nearly halves the number of pregnant women requiring insulin treatment, and does not increase the frequency of ultrasound checks or medical appointments.
BMJ OPEN DIABETES RESEARCH & CARE
(2022)
Article
Obstetrics & Gynecology
Veronika Guenther, Ibrahim Alkatout, Christoph Vollmer, Nicolai Maass, Alexander Strauss, Manfred Voigt
Summary: The study analyzed 110,047 singleton pregnancies to investigate the interaction of maternal BMI and smoking on perinatal outcomes and birth weight. Smoking during pregnancy was significantly associated with low birth weight, highlighting the importance of advising pregnant women to quit smoking to improve newborn birth weight and reduce morbidity.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Pediatrics
Maria Sonsoles Galan Arevalo, Ignacio Mahillo-Fernandez, Miguel Saenz De Pipaon, Luis Mariano Esteban, Diego Hernandez Martin, Juan Rodriguez Delgado, Jose Carlos Estevez Munoz, Mercedes Andeyro-Garcia, Roi Pineiro Perez, Ricardo Saviron-Cornudella
Summary: Newborns with fetal growth deceleration (FGD) but appropriate-for-gestational-age (AGA) weight experience catch-up growth, especially in weight and BMI, in the first year of life.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Lara Gonzalez-Garcia, Enrique Garcia-Lopez, Belen Fernandez-Colomer, Laura Mantecon-Fernandez, Sonia Lareu-Vidal, Marta Suarez-Rodriguez, Rosa Patricia Arias-Llorente, Gonzalo Solis-Sanchez
Summary: In VLBW preterm infants, there are differences in the prevalence of IUGR and EUGR based on Fenton 2013 charts and INTERGROWTH-21st standards, with good concordance between Fenton and IW-21 for IUGR. IW-21 is more restrictive than Fenton in defining EUGR, and patients diagnosed with EUGR according to IW-21 are more likely to have neonatal morbidity.
FRONTIERS IN PEDIATRICS
(2021)
Article
Biochemistry & Molecular Biology
Dan Chen, Ying-ying Wang, Sheng-peng Li, Hui-min Zhao, Feng-juan Jiang, Ya-xian Wu, Ying Tong, Qing-feng Pang
Summary: Maternal propionate supplementation can prevent glucose and lipid metabolic disturbance in IUGR, increase birth weight, improve liver function and energy expenditure.
Editorial Material
Genetics & Heredity
David M. Evans, Rachel M. Freathy
Summary: This study utilized extensive pedigree data from the Icelandic population to identify genetic effects on birth weight that differ according to parental origin, and to distinguish the contributions from the maternal intrauterine environment and offspring genetics on fetal growth.
Correction
Biochemistry & Molecular Biology
Wei-Bin Wu, Yuan-Yuan Chen, Bo Zhu, Xiao-Min Peng, Song-Wen Zhang, Mei-Ling Zhou
Article
Biochemistry & Molecular Biology
Wei-Bin Wu, Yuan-Yuan Chen, Bo Zhu, Xiao-Min Peng, Song-Wen Zhang, Mei-Ling Zhou
Article
Developmental Biology
W. -B. Wu, Y. -Y. Xu, W-W Cheng, Y. -X. Wang, Y. Liu, D. Huang, H. -J. Zhang
Article
Obstetrics & Gynecology
Fuzhen Song, Weibin Wu, Zhaoxia Qian, Guofu Zhang, Yingsheng Cheng
REPRODUCTIVE SCIENCES
(2017)
Article
Oncology
Ya-Xin Wang, Jiu-Ru Zhao, Yue-Ying Xu, Wei-Bin Wu, Hui-Juan Zhang
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2017)
Article
Cell Biology
Jiu-Ru Zhao, Wei-Wei Cheng, Ya-Xin Wang, Mei Cai, Wei-Bin Wu, Hui-Juan Zhang
CELL DEATH & DISEASE
(2018)
Article
Biochemistry & Molecular Biology
Weibin Wu, Bo Zhu, Xiaomin Peng, Meiling Zhou, Dongwei Jia, Jianxin Gu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2014)
Article
Biochemistry & Molecular Biology
Lingling Ji, Ruyi Xue, Wenqing Tang, Weibin Wu, Tingting Hu, Xijun Liu, Xiaomin Peng, Jianxin Gu, She Chen, Si Zhang
Article
Developmental Biology
W. Wu, Y. Wang, Y. Xu, Y. Liu, Y. Wang, H. Zhang
Article
Multidisciplinary Sciences
Wei-Bin Wu, Ramkumar Menon, Yue-Ying Xu, Jiu-Ru Zhao, Yan-Lin Wang, Yuan Liu, Hui-Juan Zhang
SCIENTIFIC REPORTS
(2016)
Article
Cell Biology
Weibin Wu, Qing Wu, Xinmei Liu
Article
Developmental Biology
Juan Li, Yuan Liu, Ruihong Xue, Hong Shen, Ying Wu, Martin Quinn, Huijuan Zhang, Weibin Wu
Article
Cell Biology
Xi Yang, Yulai Zhou, Huan Li, Fuzhen Song, Juan Li, Yong Zhang, Yi Lin, Huijuan Zhang, Jianxia Fan, Weibin Wu
Summary: This study revealed the complex interaction among excessive bile acids induced autophagic flux, mitochondrial dysfunction, and cellular apoptosis in placental trophoblasts, which may play a critical role in the pathogenesis of intrahepatic cholestasis of pregnancy (ICP).
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Developmental Biology
Wei-Bin Wu, Yue-Ying Xu, Wei-Wei Cheng, Bo Yuan, Jiu-Ru Zhao, Yan-Lin Wang, Hui-Juan Zhang