Collagen fiber orientation disorder from H&E images is prognostic for early stage breast cancer: clinical trial validation

Deep learning-based survival prediction for multiple cancer types using histopathology images

(2020) Ellery Wulczyn et al.   PLoS One

Artificial intelligence in digital pathology — new tools for diagnosis and precision oncology

(2019) Kaustav Bera et al.   Nature Reviews Clinical Oncology

Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer

(2018) Jon Whitney et al.   BMC CANCER

Nuclear shape and orientation features from H&E images predict survival in early-stage estrogen receptor-positive breast cancers

(2018) Cheng Lu et al.   LABORATORY INVESTIGATION

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

(2018) Joseph A. Sparano et al.   NEW ENGLAND JOURNAL OF MEDICINE

Image-based risk score to predict recurrence of ER+ breast cancer in ECOG-ACRIN Cancer Research Group E2197.

(2018) Nishant Verma et al.   JOURNAL OF CLINICAL ONCOLOGY

Pattern of Collagen Fibers and Localization of Matrix Metalloproteinase 2 and 9 during Breast Cancer Invasion

(2018) Hasnan Jaafar et al.   TUMORI

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Quantifying collagen fiber orientation in breast cancer using quantitative phase imaging

(2017) Hassaan Majeed et al.   JOURNAL OF BIOMEDICAL OPTICS

Prediction of recurrence in early stage non-small cell lung cancer using computer extracted nuclear features from digital H&E images

(2017) Xiangxue Wang et al.   Scientific Reports

Digital pathology in clinical use: where are we now and what is holding us back?

(2016) Jon Griffin et al.   HISTOPATHOLOGY

Changes of collagen ultrastructure in breast cancer tissue determined by second-harmonic generation double Stokes-Mueller polarimetric microscopy

(2016) Ahmad Golaraei et al.   Biomedical Optics Express

Remodeling of extracellular matrix due to solid stress accumulation during tumor growth

(2015) Athanassios P. Pirentis et al.   CONNECTIVE TISSUE RESEARCH

Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts

(2015) Alex J. Walsh et al.   JOURNAL OF BIOMEDICAL OPTICS

Prospective Validation of a 21-Gene Expression Assay in Breast Cancer

(2015) Joseph A. Sparano et al.   NEW ENGLAND JOURNAL OF MEDICINE

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer

(2014) Jeremy S. Bredfeldt et al.   JOURNAL OF BIOMEDICAL OPTICS

ECM stiffness paves the way for tumor cells

(2014) Victoria Seewaldt   NATURE MEDICINE

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

(2014) Janna K Mouw et al.   NATURE MEDICINE

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

(2013)   LANCET

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Systematic Analysis of Breast Cancer Morphology Uncovers Stromal Features Associated with Survival

(2011) A. H. Beck et al.   Science Translational Medicine

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine