Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy

Bilirubin as a signaling molecule

(2020) Libor Vítek   MEDICINAL RESEARCH REVIEWS

Osteoarthritis year in review 2019: epidemiology and therapy

(2020) M. Kloppenburg et al.   OSTEOARTHRITIS AND CARTILAGE

Esculentoside A protects against osteoarthritis by ameliorating inflammation and repressing osteoclastogenesis

(2020) Qing Shao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (Danio rerio)

(2020) Roberta Giordo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

pH-sensitive MOF integrated with glucose oxidase for glucose-responsive insulin delivery

(2020) Cheng Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Mussel-Inspired Polydopamine Coating Enhances the Intracutaneous Drug Delivery from Nanostructured Lipid Carriers Dependently on a Follicular Pathway

(2020) Yang Chen et al.   MOLECULAR PHARMACEUTICS

Efficient Delivery of Triptolide Plus a miR-30-5p Inhibitor Through the Use of Near Infrared Laser Responsive or CADY Modified MSNs for Efficacy in Rheumatoid Arthritis Therapeutics

(2020) Xiaonan Zhang et al.   Frontiers in Bioengineering and Biotechnology

Imperatorin suppresses IL-1β-induced iNOS expression via inhibiting ERK-MAPK/AP1 signaling in primary human OA chondrocytes

(2020) Nashrah Ahmad et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Polydopamine-based surface modification of hemoglobin particles for stability enhancement of oxygen carriers

(2020) Jilin Hu et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Protective effects and mechanisms of bilirubin nanomedicine against acute pancreatitis

(2020) Qing Yao et al.   JOURNAL OF CONTROLLED RELEASE

LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis

(2020) Manoj Arra et al.   Nature Communications

Biodegradable MRI Visible Drug Eluting Stent Reinforced by Metal Organic Frameworks

(2020) Rezvani Alanagh Hamideh et al.   Advanced Healthcare Materials

Nonsteroidal Anti-inflammatory Drugs vs Cognitive Behavioral Therapy for Arthritis Pain

(2020) Liana Fraenkel et al.   JAMA Internal Medicine

Review of the Biomolecular Modification of the Metal-Organ-Framework

(2020) Qiqi Xing et al.   Frontiers in Chemistry

pH-responsive and hyaluronic acid-functionalized metal–organic frameworks for therapy of osteoarthritis

(2020) Feng Xiong et al.   JOURNAL OF NANOBIOTECHNOLOGY

Core–Shell Nanosystems for Self-Activated Drug–Gene Combinations against Triple-Negative Breast Cancer

(2020) Peng Liu et al.   ACS Applied Materials & Interfaces

Merging metal organic framework with hollow organosilica nanoparticles as a versatile nanoplatform for cancer theranostics

(2019) Liang Chen et al.   Acta Biomaterialia

CaP coated mesoporous polydopamine nanoparticles with responsive membrane permeation ability for combined photothermal and siRNA therapy

(2019) Zhenqiang Wang et al.   Acta Biomaterialia

Drug Delivery System Based on Near-Infrared Light-Responsive Molybdenum Disulfide Nanosheets Controls the High-Efficiency Release of Dexamethasone To Inhibit Inflammation and Treat Osteoarthritis

(2019) Yingyu Zhao et al.   ACS Applied Materials & Interfaces

Thermosensitive hybrid hyaluronan/p(HPMAm‐lac)‐PEG hydrogels enhance cartilage regeneration in a mouse model of osteoarthritis

(2019) Dimitrios Agas et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nitric Oxide-Scavenging Nanogel for Treating Rheumatoid Arthritis

(2019) Jiwon Yeo et al.   NANO LETTERS

Effects of allopurinol dose escalation on bone erosion and urate volume in gout: a dual energy CT imaging study of a randomized controlled trial

(2019) Nicola Dalbeth et al.   Arthritis & Rheumatology

Targeted delivery of hesperetin to cartilage attenuates osteoarthritis by bimodal imaging with Gd2(CO3)3@PDA nanoparticles via TLR-2/NF-κB/Akt signaling

(2019) Zhengxiao Ouyang et al.   BIOMATERIALS

Isorhamnetin ameliorates inflammatory responses and articular cartilage damage in the rats of monosodium iodoacetate-induced osteoarthritis

(2019) Sen-Wei Tsai et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

UCP2 ameliorates mitochondrial dysfunction, inflammation, and oxidative stress in lipopolysaccharide-induced acute kidney injury

(2019) Yue Ding et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Versatile Polydopamine Platforms: Synthesis and Promising Applications for Surface Modification and Advanced Nanomedicine

(2019) Wei Cheng et al.   ACS Nano

Tumor-targeting photodynamic therapy based on folate-modified polydopamine nanoparticles

(2019) Shufeng Yan et al.   International Journal of Nanomedicine

Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis

(2019) Yonghyun Lee et al.   NATURE MATERIALS

LDC000067 suppresses RANKL-induced osteoclastogenesis in vitro and prevents LPS-induced osteolysis in vivo

(2019) Song Xue et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Osteoarthritis: a new short-term treatment option?

(2019) Graeme Jones et al.   LANCET

Modified ZIF-8 Nanoparticles Attenuate Osteoarthritis by Reprogramming the Metabolic Pathway of Synovial Macrophages

(2019) Feng Zhou et al.   ACS Applied Materials & Interfaces

Cartilage-targeting and dual MMP-13/pH responsive theranostic nanoprobes for osteoarthritis imaging and precision therapy

(2019) Haimin Chen et al.   BIOMATERIALS

Polydopamine-Derivated Hierarchical Nanoplatforms for Efficient Dual-Modal Imaging-Guided Combination in Vivo Cancer Therapy

(2018) Lijiao Ao et al.   ACS Applied Materials & Interfaces

Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis

(2018) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirolimus-coated, poly(l-lactic acid)-modified polypropylene mesh with minimal intra-peritoneal adhesion formation in a rat model

(2018) S. Lu et al.   Hernia

Oxymatrine exerts protective effects on osteoarthritis via modulating chondrocyte homoeostasis and suppressing osteoclastogenesis

(2018) Yafei Jiang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bilirubin photoisomers in rhesus monkey serum

(2018) Hitoshi Okada et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Chondrocyte affinity peptide modified PAMAM conjugate as a nanoplatform for targeting and retention in cartilage

(2018) Qing Hu et al.   Nanomedicine

MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12

(2018) Wei-Shiung Lian et al.   Cell Death & Disease

Bandgap Engineered Polypyrrole–Polydopamine Hybrid with Intrinsic Raman and Photoacoustic Imaging Contrasts

(2018) Qinrui Lin et al.   NANO LETTERS

Intra-articular treatment options for knee osteoarthritis

(2018) Ian A. Jones et al.   Nature Reviews Rheumatology

Protective effects of mitochondria-targeted antioxidants and statins on cholesterol-induced osteoarthritis

(2017) Saba Farnaghi et al.   FASEB JOURNAL

Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis

(2017) Bruno R da Costa et al.   LANCET

Mesoporous polydopamine nanoparticles with co-delivery function for overcoming multidrug resistance via synergistic chemo-photothermal therapy

(2017) Yuxin Xing et al.   Nanoscale

Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis

(2017) Oscar Alvarez-Garcia et al.   Arthritis & Rheumatology

Thermoresponsive nanospheres with independent dual drug release profiles for the treatment of osteoarthritis

(2016) Mi-Lan Kang et al.   Acta Biomaterialia

Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy

(2016) Yonghyun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

(2016) Sergio Portal-Núñez et al.   BIOCHEMICAL PHARMACOLOGY

ROS/oxidative stress signaling in osteoarthritis

(2016) Panagiotis Lepetsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy prevents age-related OA

(2015) João H. Duarte   Nature Reviews Rheumatology

Mitochondrial respiration and redox coupling in articular chondrocytes

(2015) Rachel S Lane et al.   ARTHRITIS RESEARCH & THERAPY

Rapamycin-induced autophagy activity promotes bone fracture healing in rats

(2015) GE YANG et al.   Experimental and Therapeutic Medicine

Bilirubin inhibits the up-regulation of inducible nitric oxide synthase by scavenging reactive oxygen species generated by the toll-like receptor 4-dependent activation of NADPH oxidase

(2015) Gila Idelman et al.   Redox Biology

Effect of pH-Responsive Alginate/Chitosan Multilayers Coating on Delivery Efficiency, Cellular Uptake and Biodistribution of Mesoporous Silica Nanoparticles Based Nanocarriers

(2014) Wei Feng et al.   ACS Applied Materials & Interfaces

Intra-articular administration of gelatin hydrogels incorporating rapamycin–micelles reduces the development of experimental osteoarthritis in a murine model

(2014) Tokio Matsuzaki et al.   BIOMATERIALS

The role of mitochondrial reactive oxygen species in cartilage matrix destruction

(2014) Kendra N. Reed et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Size Effect on Cell Uptake in Well-Suspended, Uniform Mesoporous Silica Nanoparticles

(2009) Fang Lu et al.   Small

Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage

(2008) Dominique A. Rothenfluh et al.   NATURE MATERIALS