A Mitochondrial Oxidative Stress Amplifier to Overcome Hypoxia Resistance for Enhanced Photodynamic Therapy

A Bionanozyme with Ultrahigh Activity Enables Spatiotemporally Controlled Reactive Oxygen Species Generation for Cancer Therapy

(2021) Zhen Xu et al.   ADVANCED FUNCTIONAL MATERIALS

Effective nanotherapeutic approach for metastatic breast cancer treatment by supplemental oxygenation and imaging-guided phototherapy

(2020) Jialing Hu et al.   Nano Research

Clinical development and potential of photothermal and photodynamic therapies for cancer

(2020) Xingshu Li et al.   Nature Reviews Clinical Oncology

Molecular Design of Conjugated Small Molecule Nanoparticles for Synergistically Enhanced PTT/PDT

(2020) Wei Shao et al.   Nano-Micro Letters

Modulation of Intracellular Oxygen Pressure by Dual-Drug Nanoparticles to Enhance Photodynamic Therapy

(2019) Ya-Tong Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Carbon-dot-supported atomically dispersed gold as a mitochondrial oxidative stress amplifier for cancer treatment

(2019) Ningqiang Gong et al.   Nature Nanotechnology

Porous platinum nanoparticles as a high-Z and oxygen generating nanozyme for enhanced radiotherapy in vivo

(2019) Yan Li et al.   BIOMATERIALS

Overcoming Hypoxia by Multistage Nanoparticle Delivery System to Inhibit Mitochondrial Respiration for Photodynamic Therapy

(2019) Donglin Xia et al.   ADVANCED FUNCTIONAL MATERIALS

Boosting the photodynamic therapy efficiency with a mitochondria-targeted nanophotosensitizer

(2019) Limin Yang et al.   CHINESE CHEMICAL LETTERS

Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

(2019) Wenjia Zhang et al.   Nature Communications

An iridium(III)-palladium(II) metal−organic cage for efficient mitochondria-targeted photodynamic therapy

(2019) Chaojie Li et al.   CHINESE CHEMICAL LETTERS

Nanozyme Decorated Metal–Organic Frameworks for Enhanced Photodynamic Therapy

(2018) Yan Zhang et al.   ACS Nano

Innovative Strategies for Hypoxic-Tumor Photodynamic Therapy

(2018) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phthalocyanine-Assembled Nanodots as Photosensitizers for Highly Efficient Type I Photoreactions in Photodynamic Therapy

(2018) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The impact of light irradiation timing on the efficacy of nanoformula-based photo/chemo combination therapy

(2018) Yafang Xiao et al.   Journal of Materials Chemistry B

Biomimetic Nanoemulsions for Oxygen Delivery In Vivo

(2018) Jia Zhuang et al.   ADVANCED MATERIALS

Overcoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment

(2018) Kaitlin Graham et al.   International Journal of Nanomedicine

Nanocatalytic Tumor Therapy by Biomimetic Dual Inorganic Nanozyme-Catalyzed Cascade Reaction

(2018) Shanshan Gao et al.   Advanced Science

A Mitochondria-Targeted Cryptocyanine-Based Photothermogenic Photosensitizer

(2017) Hyo Sung Jung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Facile Ion-Doping Strategy To Regulate Tumor Microenvironments for Enhanced Multimodal Tumor Theranostics

(2017) Jing Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitochondria-targeting near-infrared light-triggered thermosensitive liposomes for localized photothermal and photodynamic ablation of tumors combined with chemotherapy

(2017) Caixia Yue et al.   Nanoscale

Redox-triggered activation of nanocarriers for mitochondria-targeting cancer chemotherapy

(2017) Wei Zhou et al.   Nanoscale

Anticancer Effect of α-Tocopheryl Succinate Delivered by Mitochondria-Targeted Mesoporous Silica Nanoparticles

(2016) Qiuyu Qu et al.   ACS Applied Materials & Interfaces

A Mitochondria-Targeted Photosensitizer Showing Improved Photodynamic Therapy Effects Under Hypoxia

(2016) Wen Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overcoming the Achilles' heel of photodynamic therapy

(2016) Wenpei Fan et al.   CHEMICAL SOCIETY REVIEWS

Mitochondria-Targeting Magnetic Composite Nanoparticles for Enhanced Phototherapy of Cancer

(2016) Ranran Guo et al.   Small

Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells

(2016) Pengying Li et al.   Scientific Reports

A Near-Infrared Triggered Nanophotosensitizer Inducing Domino Effect on Mitochondrial Reactive Oxygen Species Burst for Cancer Therapy

(2015) Zhengze Yu et al.   ACS Nano

Targeted delivery of doxorubicin to mitochondria using mesoporous silica nanoparticle nanocarriers

(2015) Qiuyu Qu et al.   Nanoscale

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

The Role of Alpha Tocopheryl Succinate (α-TOS) as a Potential Anticancer Agent

(2013) Aracely Angulo-Molina et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Extracellular adenosine triphosphate and adenosine in cancer

(2010) J Stagg et al.   ONCOGENE

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-Infrared Mesoporous Silica Nanoparticles for Optical Imaging: Characterization and In Vivo Biodistribution

(2008) Chia-Hung Lee et al.   ADVANCED FUNCTIONAL MATERIALS

The tumor microenvironment and its contribution to tumor evolution toward metastasis

(2008) Girieca Lorusso et al.   HISTOCHEMISTRY AND CELL BIOLOGY

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

(2008) L-F Dong et al.   ONCOGENE

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE