Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation

Improving reporting standards for polygenic scores in risk prediction studies

(2021) Hannah Wand et al.   NATURE

An Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

(2021) Fernando Riveros-Mckay et al.   Circulation-Genomic and Precision Medicine

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

(2020) Joshua Elliott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

(2020) Jonathan D. Mosley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups

(2020) Ozan Dikilitas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation

(2019) Craig T. January et al.   CIRCULATION

Genomic prediction of cognitive traits in childhood and adolescence

(2019) A. G. Allegrini et al.   MOLECULAR PSYCHIATRY

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

(2019) Gad Abraham et al.   Nature Communications

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants

(2018) Loes CA Rutten-Jacobs et al.   BMJ-British Medical Journal

Polygenic scores via penalized regression on summary statistics

(2017) Timothy Shin Heng Mak et al.   GENETIC EPIDEMIOLOGY

Predictive performance of the CHA2DS2-VASc rule in atrial fibrillation: a systematic review and meta-analysis

(2017) S. van Doorn et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

(2017) José A López-López et al.   BMJ-British Medical Journal

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis

(2017) José A López-López et al.   BMJ-British Medical Journal

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Clinical Interpretation and Implications of Whole-Genome Sequencing

(2014) Frederick E. Dewey et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CHADS2, CHA2DS2-VASc, and long-term stroke outcome in patients without atrial fibrillation

(2013) G. Ntaios et al.   NEUROLOGY

Genetic Heritability of Ischemic Stroke and the Contribution of Previously Reported Candidate Gene and Genomewide Associations

(2012) Steve Bevan et al.   STROKE

Clinical assessment incorporating a personal genome

(2010) Euan A Ashley et al.   LANCET

Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach

(2009) Gregory Y.H. Lip et al.   CHEST