4.6 Article

Factors Affecting the Spatial Resolution in 2D Grating-Based X-Ray Phase Contrast Imaging

Journal

FRONTIERS IN PHYSICS
Volume 9, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fphy.2021.672207

Keywords

X-ray imaging; spatial resolution; phase contrast; angular spectrum algorithm; the spatial harmonic method

Funding

  1. National Natural Science Foundation of China [61827825, 61735017]
  2. Key Research and Development Program of Zhejiang Province [2020C01116]
  3. Fundamental Research Funds for the Central Universities [2019XZZX003-06, K20200132]
  4. Zhejiang Lab [2018EB0ZX01, 2020MC0AE01]

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This paper simulates factors affecting spatial resolution in a typical 2D grating-based phase contrast imaging system, based on scalar diffraction theory and operator theory of imaging. It discusses methods to improve image quality and the limitation of the grating-to-detector distance in the spatial harmonic method.
X-ray phase contrast imaging is a promising technique in X-ray biological microscopy, as it improves the contrast of images for materials with low electron density compared to traditional X-ray imaging. The spatial resolution is an important parameter to evaluate the image quality. In this paper, simulation of factors which may affect the spatial resolution in a typical 2D grating-based phase contrast imaging system is conducted. This simulation is based on scalar diffraction theory and the operator theory of imaging. Absorption, differential phase contrast, and dark-field images are retrieved via the Fourier transform method. Furthermore, the limitation of the grating-to-detector distance in the spatial harmonic method is discussed in detail.

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