Article
Public, Environmental & Occupational Health
Samantha Simon, Brian Hollenbeck
Summary: This retrospective cohort study identified risk factors for surgical site infection (SSI) in patients with hip and knee arthroplasty. Active smoking and revision arthroplasty both increased the risk of SSI. Former smokers had a lower risk of SSI, suggesting the potential benefit of implementing mandatory smoking cessation programs.
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Article
Dermatology
Jiwen Zhu, Mengdi Si, Zongqiang Huang
Summary: The meta-analysis aims to evaluate and compare the impact of tobacco usage on surgical site wound problems (SSWPs) after primary total hip and total knee arthroplasty (PTH & TKA). A total of 15 studies from 2001 to 2023 were analyzed, including 560,819 individuals with PTH & TKA. The results showed that smokers had significantly higher SSWPs compared with non-smokers in this population.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Dermatology
Zhengwu Lin, Te Chen, Guofu Chen, Wenjun Pan, Wei Xu
Summary: The application of a tourniquet (TNQ) in total knee arthroplasty (TKA) is controversial. This meta-analysis found that the use of TNQ during TKA increases the risk of postoperative surgical site wound infection and worsens short-term postoperative wound pain.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Medicine, General & Internal
Ting-Yu Hung, Kuan-Lin Liu, Shu-Hui Wen
Summary: This study evaluated the risk of surgical site infection (SSI) after total knee arthroplasty (TKA) and identified sex-related differences. The presence of specific comorbid conditions was found to significantly increase the risk of SSI, and differences were observed between male and female patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dermatology
Haihong Li, Yina Li, Danhua Wang, Qiuli Huang, Dandan Liu
Summary: This research aimed to identify the risk factors associated with surgical site infections (SSIs) after total knee arthroplasty (TKA) in elderly osteoarthritis patients, in order to improve post-surgical outcomes. The study found that age, BMI, smoking history, and diabetes diagnosis were significant risk factors for post-TKA infections. Other factors such as ASA classification, surgical duration, and intraoperative hemorrhage also contributed to the risk landscape.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Orthopedics
Peter A. Gold, Luke J. Garbarino, Prem N. Ramkumar, Hiba Anis, Nipun Sodhi, Sean J. Matuszak, Michael A. Mont
Summary: This study found an increased risk of deep surgical site infections (SSIs) in patients with psoriasis after total knee arthroplasty (TKA). Therefore, increased pre-operative counseling, shared decision-making, and infectious precautions are necessary in the TKA population with psoriasis, and attention should be paid to the comorbidities of psoriasis patients.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Dermatology
Jing Han, Xin-Ju Liu
Summary: This study systematically evaluated the effects of clinical nursing pathway interventions on surgical site wound infections and postoperative complications in patients after undergoing total knee arthroplasty (TKA). The meta-analysis results showed that clinical nursing pathways significantly reduced the incidence of wound infections and postoperative complications in patients undergoing TKA.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Dermatology
Haiying Lu, Jinjiao Yu, Huiqin Hong
Summary: This meta-analysis investigated the effects of the enhanced recovery after surgery (ERAS) nursing program on surgical wound infection (SWI) and postoperative complications in patients undergoing total knee arthroplasty (TKA). The results showed that the rates of SWI and postoperative complications were significantly lower in the ERAS intervention group compared to the control group. Therefore, ERAS intervention can effectively reduce the occurrence of SWI and postoperative complications, and have a remarkable rehabilitation effect that can be widely used in clinical settings.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Dermatology
Yankun Luo, Junfeng Gong, Shuyuan Yang
Summary: A meta-analysis study found that patients with end-stage renal disease (ESRD) undergoing dialysis or kidney transplant have a higher risk of surgical site wound infection (SSWI) after knee and hip arthroplasty. There was no significant difference between dialysis and renal transplant in terms of postoperative SSWI and prosthetic joint infection, but dialysis patients had a significantly higher risk of prosthetic joint infection compared to renal transplant patients.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Orthopedics
Ryota Yamagami, Hiroshi Inui, Taisuke Jo, Manabu Kawata, Shuji Taketomi, Kenichi Kono, Kohei Kawaguchi, Shin Sameshima, Tomofumi Kage, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Sakae Tanaka
Summary: UKA is associated with lower risk of SSI and PJI compared to TKA, and should be carefully considered in high-risk patients.
Article
Medicine, General & Internal
Ming-Yi Duan, Hang-Zhou Zhang
Summary: The study found that prophylactic irrigation with vancomycin solution significantly reduces the incidence of acute surgical site infection after total joint arthroplasty, without increasing the rate of wound healing complications.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Public, Environmental & Occupational Health
Kwadwo Mponponsuo, Jenine Leal, Shannon Puloski, Derek Chew, Swati Chavda, Flora Au, Elissa Rennert-May
Summary: The study evaluated the cost of 1-stage and 2-stage revisions, debridement, antibiotic and implant retention for complex surgical site infections following hip and knee replacements. Results showed that the medical costs were highest at 12 months, with age and chronic complications impacting cost increases. Further research is needed to explore the correlation between surgical outcomes and costs to improve patient care.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Multidisciplinary Sciences
Ho-Ken Chung, Shu-Hui Wen, Wei-Chuan Chang, Kuan-Lin Liu
Summary: Patients with rheumatoid arthritis do not have a higher risk of acute surgical site infection after total knee arthroplasty compared to patients with osteoarthritis. The current treatment strategy for rheumatoid arthritis patients requiring TKA is deemed safe and appropriate.
SCIENTIFIC REPORTS
(2021)
Article
Orthopedics
Richard Rahardja, Arthur J. Morris, Gary J. Hooper, Nikki Grae, Christopher M. Frampton, Simon W. Young
Summary: This study analyzed data from two databases in New Zealand and found that the use of surgical helmet systems (SHSs) was associated with a lower rate of prosthetic joint infection (PJI) after total knee arthroplasty (TKA). Male sex and higher American Society of Anesthesiologists (ASA) score were identified as risk factors for infection.
JOURNAL OF ARTHROPLASTY
(2022)
Article
Orthopedics
Sergi Gil-Gonzalez, Ricardo Andres Barja-Rodriguez, Antoni Lopez-Pujol, Hussein Berjaoui, Jose Enrique Fernandez-Bengoa, Juan Ignacio Erquicia, Joan Leal-Blanquet, Xavier Pelfort
Summary: This study found that the use of continuous passive motion (CPM) after total knee arthroplasty (TKA) does not improve flexion mobility or decrease pain. However, it does have a beneficial effect in reducing the severity of hematoma. There were no significant differences in surgical wound aspect (SWA) and pain management between the CPM and no-CPM groups.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Orthopedics
Miao-Tian Tang, Shang Li, Xiao Liu, Xiang Huang, Dian-Ying Zhang, Ming-Xing Lei
Summary: By retrospectively analyzing data of hip fracture patients, this study found an association between dementia and postoperative pneumonia and successfully developed an algorithm to predict the risk of developing postoperative pneumonia. The algorithm includes nine predictors and shows good predictive ability in internal and external validation.
ORTHOPAEDIC SURGERY
(2022)
Article
Psychiatry
Yue Li, Shengyang Jin, Ya Li, Fei Guo, Ting Luo, Bo Pan, Mingxing Lei, Yaosheng Liu
Summary: This study examined the mental health and research activities of biomedical students in China. The findings revealed a high prevalence of anxiety and depression among these students, and longer research work duration was associated with higher levels of anxiety and depression. It is recommended that biomedical students limit their research work to no more than 7 hours a day to maintain a balance between mental health and scientific research achievements.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Orthopedics
Shengjie Wang, Fan Xiong, Yanzheng Gao, Mingxing Lei, Xianlong Zhang
Summary: This study investigated the characteristics of clinical trials related to hip fractures registered at ClinicalTrials.gov and identified potential risk factors associated with completion. The results showed that a considerable proportion of the trials were completed, but only a small fraction of the results were presented on the ClinicalTrials.gov website. Independent risk factors affecting recruitment status and completion time were also identified.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Public, Environmental & Occupational Health
Yaosheng Liu, Xuyong Cao, Xiongwei Zhao, Xiaolin Shi, Mingxing Lei, Haifeng Qin
Summary: This study aimed to investigate the quality of life and mental health status among advanced cancer patients with spine metastases. The results showed that these patients had poor quality of life and experienced severe anxiety and depression. Age was found to be significantly associated with quality of life, anxiety, and depression. Additionally, factors such as dietary preferences, time since cancer diagnosis, surgical treatment, hormone endocrine therapy, and economic burden due to cancer treatments were also associated with quality of life.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Jinglan Li, Xuanlong Li, Mingxing Lei, Wanyue Li, Wenqian Chen, Tianju Ma, Yi Gao, Zi Ye, Zhaohui Li
Summary: This study aimed to assess the risk factors and establish a model for predicting worsening diabetic retinopathy (DR-worsening) within five years after panretinal photocoagulation (PRP) treatment.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Immunology
Mingxing Lei, Zhencan Han, Shengjie Wang, Chunxue Guo, Xianlong Zhang, Ya Song, Feng Lin, Tianlong Huang
Summary: This study developed a reliable prediction model using machine learning techniques to improve early diagnosis and intervention of Persistent Critical Illness (PerCI). The dynamic changes of lymphocytes were identified as a reliable biomarker for PerCI development.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Yunpeng Cui, Xuedong Shi, Shengjie Wang, Yong Qin, Bailin Wang, Xiaotong Che, Mingxing Lei
Summary: This study aims to develop an accurate prediction model using machine-learning techniques to predict 3-month mortality among lung cancer patients with bone metastases. The results can assist clinicians in assessing patients' risks and providing guidance for treatment decisions.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Oncology
Yue Li, Ze Long, Xiuju Wang, Mingxing Lei, Chunzi Liu, Xiaolin Shi, Yaosheng Liu
Summary: This study aimed to stratify patient populations for whom quality of life assessment should be encouraged by developing and validating a nomogram to predict quality of life among advanced cancer patients with spinal metastases. The nomogram, developed using the LASSO approach with 10-fold cross-validation, showed good discrimination, calibration, and clinical usefulness. Patients in the high-risk group had over four times higher likelihood of experiencing a poor quality of life compared to those in the low-risk group.
Article
Critical Care Medicine
Mingxing Lei, Zhencan Han, Shengjie Wang, Tao Han, Shenyun Fang, Feng Lin, Tianlong Huang
Summary: This study aimed to develop and validate a model for estimating the risk of in-hospital mortality in critically ill patients with hip fracture. The model showed good discrimination and calibration, and the web-based calculator based on this model can be used to predict the risk of mortality in ICU settings.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Oncology
Yunpeng Cui, Qiwei Wang, Xuedong Shi, Qianwen Ye, Mingxing Lei, Bailin Wang
Summary: This study aimed to predict the three-month mortality of bone metastasis patients with cancer of unknown primary (CUP) using machine learning-based techniques. The random forest model showed the best performance in prediction, and a web calculator based on this model can help guide clinical decision-making and facilitate therapeutic communication between patients and physicians.
FRONTIERS IN ONCOLOGY
(2022)
Article
Clinical Neurology
Le Gao, Yuncen Cao, Xuyong Cao, Xiaolin Shi, Mingxing Lei, Xiuyun Su, Yaosheng Liu
Summary: This study proposes a precise model based on machine learning techniques to predict the psychological status of cancer patients with spinal metastatic disease. It identifies factors such as age, gender, smoking and drinking that are associated with psychological health. The gradient boosting machine algorithm performs the best in predicting the outcome.
Article
Oncology
Ze Long, Min Yi, Yong Qin, Qianwen Ye, Xiaotong Che, Shengjie Wang, Mingxing Lei
Summary: The study aims to build a reliable model to predict early mortality among hepatocellular carcinoma (HCC) patients with bone metastases using an ensemble machine learning technique. A cohort of 124,770 patients with HCC and 1897 patients with bone metastases were included in the study. Five machine learning techniques were employed to train and optimize models, and an ensemble machine learning technique was used to generate risk probability by combining the results from multiple algorithms. The results show that the model accurately predicts early mortality and can be used for clinical decision-making.
FRONTIERS IN ONCOLOGY
(2023)
Article
Cell Biology
Mingxing Lei, Wenjing Zheng, Yuncen Cao, Xuyong Cao, Xiaolin Shi, Xiuyun Su, Yaosheng Liu
Summary: This study aimed to introduce a new medical pathway based on enhanced recovery after surgery (ERAS) for patients with metastatic epidural spinal cord compression (MESCC) and investigate the improvement of clinical metrics. The results showed that ERAS intervention was beneficial in reducing intraoperative blood loss, length of hospital stay, promoting recovery and treatment process, and improving patient satisfaction.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Health Care Sciences & Services
Mingxing Lei, Bing Wu, Zhicheng Zhang, Yong Qin, Xuyong Cao, Yuncen Cao, Baoge Liu, Xiuyun Su, Yaosheng Liu
Summary: This study develops a machine learning-based calculator to assess the probability of early death among patients with bone metastasis. The calculator has the potential to guide clinical decision-making and improve the care of patients with bone metastasis.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Orthopedics
Yuan Gao, Xiao-Jie Fu, Ming-Xing Lei, Peng-Bin Yin, Yu-Tong Meng, Qing-Mei Wang, Hong-Ying Pi
Summary: This study aimed to develop an information platform based on a mobile application to improve drug compliance and reduce the incidence of VTE in hip fracture patients. The results showed that nursing intervention based on the information platform significantly improved drug compliance and reduced the occurrence of VTE.
CHINESE JOURNAL OF TRAUMATOLOGY
(2022)