Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2

In a search for potential drug candidates for combating COVID-19: computational study revealed salvianolic acid B as a potential therapeutic targeting 3CLpro and spike proteins

(2021) Ayman Abo Elmaaty et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor

(2021) Ahmed A. Al-Karmalawy et al.   Frontiers in Chemistry

Revisiting Activity of Some Nocodazole Analogues as a Potential Anticancer Drugs Using Molecular Docking and DFT Calculations

(2021) Muhammad Khattab et al.   Frontiers in Chemistry

Strong Inhibitory Activity and Action Modes of Synthetic Maslinic Acid Derivative on Highly Pathogenic Coronaviruses: COVID-19 Drug Candidate

(2021) Raya Soltane et al.   Pathogens

Sinapic Acid Suppresses SARS CoV-2 Replication by Targeting Its Envelope Protein

(2021) Raha Orfali et al.   Antibiotics-Basel

Bioassay-guided isolation of a new cytotoxic ceramide from Cyperus rotundus L.

(2021) Reham M. Samra et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies

(2021) Ahmed A. Zaki et al.   Journal of Traditional and Complementary Medicine

Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia

(2020) Daniel K W Chu et al.   CLINICAL CHEMISTRY

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

Antiviral Activities of Quercetin and Isoquercitrin Against Human Herpesviruses

(2020) Chae Hyun Kim et al.   MOLECULES

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

Virucidal Action Against Avian Influenza H5N1 Virus and Immunomodulatory Effects of Nanoformulations Consisting of Mesoporous Silica Nanoparticles Loaded with Natural Prodrugs

(2020) Khaled AbouAitah et al.   International Journal of Nanomedicine

May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence

(2020) Giuseppe Annunziata et al.   Frontiers in Medicine

EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2

(2020) Wael H. Roshdy et al.   PLoS One

FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2

(2020) Ahmed Mostafa et al.   Pharmaceuticals

Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence

(2019) Marziyeh Hajialyani et al.   MOLECULES

Computational Approaches for Drug Discovery

(2019) Brogi   MOLECULES

Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study

(2018) Mohammad K. Parvez et al.   SAUDI PHARMACEUTICAL JOURNAL

Synergistic antiviral effect of curcumin functionalized graphene oxide against respiratory syncytial virus infection

(2017) Xiao Xi Yang et al.   Nanoscale

Antiviral Properties of the Natural Polyphenols Delphinidin and Epigallocatechin Gallate against the Flaviviruses West Nile Virus, Zika Virus, and Dengue Virus

(2017) Ángela Vázquez-Calvo et al.   Frontiers in Microbiology

Curcumin affects gene expression and reactive oxygen species via a PKA dependent mechanism in Dictyostelium discoideum

(2017) William S. Swatson et al.   PLoS One

Curcumin Shows Antiviral Properties against Norovirus

(2016) Minji Yang et al.   MOLECULES

Effect of Quercetin on Hepatitis C Virus Life Cycle: From Viral to Host Targets

(2016) Ángela Rojas et al.   Scientific Reports

Virucidal efficacy of treatment with photodynamically activated curcumin on murine norovirus bio-accumulated in oysters

(2015) Juan Wu et al.   Photodiagnosis and Photodynamic Therapy

Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry

(2015) Wenjiao Wu et al.   Viruses-Basel

Curcumin, a component of golden spice: From bedside to bench and back

(2014) Sahdeo Prasad et al.   BIOTECHNOLOGY ADVANCES

A dual character of flavonoids in influenza A virus replication and spread through modulating cell-autonomous immunity by MAPK signaling pathways

(2014) Wenjuan Dong et al.   Scientific Reports

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

(2014) Soheil Zorofchian Moghadamtousi et al.   Biomed Research International

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

(2013) Anggakusuma et al.   GUT

Inhibition of Enveloped Viruses Infectivity by Curcumin

(2013) Tzu-Yen Chen et al.   PLoS One

Antiviral Activity of Baicalein and Quercetin against the Japanese Encephalitis Virus

(2012) Jefree Johari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anticancer effect and mechanism of polymer micelle-encapsulated quercetin on ovarian cancer

(2012) Xiang Gao et al.   Nanoscale

Inhibitory effects of quercetin 3-rhamnoside on influenza A virus replication

(2009) Hwa Jung Choi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Quercetin in a lotus leaves extract may be responsible for antibacterial activity

(2008) Mingyu Li et al.   ARCHIVES OF PHARMACAL RESEARCH

Transepithelial transport of hesperetin and hesperidin in intestinal Caco-2 cell monolayers

(2007) Shoko Kobayashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES