Exploring the Ability of Meningococcal Vaccines to Elicit Mucosal Immunity: Insights from Humans and Mice

Meningococcal B Vaccine and Meningococcal Carriage in Adolescents in Australia

(2020) Helen S. Marshall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Difference in virulence between Neisseria meningitidis serogroups W and Y in transgenic mice

(2020) Lorraine Eriksson et al.   BMC MICROBIOLOGY

Next-Generation Pertussis Vaccines Based on the Induction of Protective T Cells in the Respiratory Tract

(2020) Caitlín Ní Chasaide et al.   Vaccines

Immunization with whole cell but not acellular pertussis vaccines primes CD4 TRM cells that sustain protective immunity against nasal colonization with Bordetella pertussis

(2019) Mieszko M. Wilk et al.   Emerging Microbes & Infections

Impact of a mass vaccination campaign against Serogroup B meningococcal disease in the Saguenay-Lac-Saint-Jean region of Quebec four years after its launch

(2019) G. Deceuninck et al.   VACCINE

A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine

(2019) Peter T. Beernink et al.   mBio

Global estimate of Neisseria meningitidis serogroups proportion in invasive meningococcal disease: A systematic review and meta-analysis

(2019) Ali Purmohamad et al.   MICROBIAL PATHOGENESIS

From research to licensure and beyond: clinical development of MenB-FHbp, a broadly protective meningococcal B vaccine

(2018) John L. Perez et al.   Expert Review of Vaccines

B Part of It protocol: a cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage ofNeisseria meningitidisin adolescents

(2018) Helen S Marshall et al.   BMJ Open

Impact of meningococcal vaccination on carriage and disease transmission: A review of the literature

(2018) Paul Balmer et al.   Human Vaccines & Immunotherapeutics

Progress toward the global control of Neisseria meningitidis: 21st century vaccines, current guidelines, and challenges for future vaccine development

(2018) A. W. Dretler et al.   Human Vaccines & Immunotherapeutics

Atmospheric Dust, Early Cases, and Localized Meningitis Epidemics in the African Meningitis Belt: An Analysis Using High Spatial Resolution Data

(2018) Maxime Woringer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine

(2018) Luis Solans et al.   Mucosal Immunology

The Global Meningococcal Initiative meeting on prevention of meningococcal disease worldwide: Epidemiology, surveillance, hypervirulent strains, antibiotic resistance and high-risk populations

(2018) Reinaldo Acevedo et al.   Expert Review of Vaccines

Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines

(2018) Ximei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the mechanisms of conjugate vaccines

(2018) Rino Rappuoli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of strain coverage of the multicomponent meningococcal serogroup B vaccine (4CMenB) administered in infants according to different immunisation schedules

(2018) Alessia Biolchi et al.   Human Vaccines & Immunotherapeutics

Discordant Effects of Licensed Meningococcal Serogroup B Vaccination on Invasive Disease and Nasal Colonization in a Humanized Mouse Model

(2017) Carolyn M. Buckwalter et al.   JOURNAL OF INFECTIOUS DISEASES

A phase III observer-blind randomized, controlled study to evaluate the immune response and the correlation with nasopharyngeal carriage after immunization of university students with a quadrivalent meningococcal ACWY glycoconjugate or serogroup B meningococcal vaccine

(2017) Robert C. Read et al.   VACCINE

Successful African introduction of a new Group A meningococcal conjugate vaccine: Future challenges and next steps

(2017) F. Marc LaForce et al.   Human Vaccines & Immunotherapeutics

Presentation with gastrointestinal symptoms and high case fatality associated with group W meningococcal disease (MenW) in teenagers, England, July 2015 to January 2016

(2016) Helen Campbell et al.   Eurosurveillance

Fighting Neisseria meningitidis: past and current vaccination strategies

(2016) Giulia Piccini et al.   Expert Review of Vaccines

The Global Meningococcal Initiative: global epidemiology, the impact of vaccines on meningococcal disease and the importance of herd protection

(2016) Ray Borrow et al.   Expert Review of Vaccines

The Global Evolution of Meningococcal Epidemiology Following the Introduction of Meningococcal Vaccines

(2016) Stephen I. Pelton   JOURNAL OF ADOLESCENT HEALTH

Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage

(2016) E Mitsi et al.   Mucosal Immunology

Clinical experience with the meningococcal B vaccine, Bexsero ® : Prospects for reducing the burden of meningococcal serogroup B disease

(2016) Philip S. Watson et al.   VACCINE

Characterization of invasive Neisseria meningitidis strains from Québec, Canada, during a period of increased serogroup B disease, 2009-2013: phenotyping and genotyping with special emphasis on the non-carbohydrate protein vaccine targets

(2015) Dennis K.S. Law et al.   BMC MICROBIOLOGY

Impaired Immunogenicity of Meningococcal Neisserial Surface Protein A in Human Complement Factor H Transgenic Mice

(2015) Eduardo Lujan et al.   INFECTION AND IMMUNITY

Serum bactericidal antibody assays – The role of complement in infection and immunity

(2015) E.D.G. McIntosh et al.   VACCINE

Persistent low carriage of serogroup A Neisseria meningitidistwo years after mass vaccination with the meningococcal conjugate vaccine, MenAfriVac

(2014) Paul A Kristiansen et al.   BMC INFECTIOUS DISEASES

A Decade of Herd Protection After Introduction of Meningococcal Serogroup C Conjugate Vaccination

(2014) Merijn W. Bijlsma et al.   CLINICAL INFECTIOUS DISEASES

Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities

(2014) Rafael Frandoloso et al.   INFECTION AND IMMUNITY

Sterilizing Immunity Elicited by Neisseria meningitidis Carriage Shows Broader Protection than Predicted by Serum Antibody Cross-Reactivity inCEACAM1-Humanized Mice

(2014) Kay O. Johswich et al.   INFECTION AND IMMUNITY

Protection against Streptococcus pneumoniae lung infection after nasopharyngeal colonization requires both humoral and cellular immune responses

(2014) R Wilson et al.   Mucosal Immunology

Antibody blocks acquisition of bacterial colonization through agglutination

(2014) A M Roche et al.   Mucosal Immunology

Bexsero® chronicle

(2014) George Vernikos et al.   Pathogens and Global Health

Epidemiological changes in meningococcal meningitis in Niger from 2008 to 2011 and the impact of vaccination

(2013) Jean-Marc Collard et al.   BMC INFECTIOUS DISEASES

Bactericidal antibody against a representative epidemiological meningococcal serogroup B panel confirms that MATS underestimates 4CMenB vaccine strain coverage

(2013) Giacomo Frosi et al.   VACCINE

Diversity of Canadian meningococcal serogroup B isolates and estimated coverage by an investigational meningococcal serogroup B vaccine (4CMenB)

(2013) Julie A. Bettinger et al.   VACCINE

In Vivo Adaptation and Persistence of Neisseria meningitidis within the Nasopharyngeal Mucosa

(2013) Kay O. Johswich et al.   PLoS Pathogens

Impact of the Serogroup A Meningococcal Conjugate Vaccine, MenAfriVac, on Carriage and Herd Immunity

(2012) Paul A. Kristiansen, Fabien Diomandé, Absatou Ky Ba, Idrissa Sanou, Abdoul–Salam Ouédraogo, Rasmata Ouédraogo, Lassana Sangaré, Denis Kandolo, Flavien Aké, Inger Marie Saga, Thomas A. Clark, Lara Misegades, Stacey W. Martin, Jennifer Dolan Thomas, Sylvestre R. Tiendrebeogo, Musa Hassan-King, Mamoudou H. Djingarey, Nancy E. Messonnier, Marie-Pierre Préziosi, F. Marc LaForce, Dominique A. Caugant   CLINICAL INFECTIOUS DISEASES

Serogroup A meningococcal conjugate vaccination in Burkina Faso: analysis of national surveillance data

(2012) Ryan T Novak et al.   LANCET INFECTIOUS DISEASES

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens

(2012) Davide Serruto et al.   VACCINE

Meningococcal disease: Clinical presentation and sequelae

(2012) David Pace et al.   VACCINE

"Herd Immunity": A Rough Guide

(2011) P. Fine et al.   CLINICAL INFECTIOUS DISEASES

Combined Roles of Human IgG Subclass, Alternative Complement Pathway Activation, and Epitope Density in the Bactericidal Activity of Antibodies to Meningococcal Factor H Binding Protein

(2011) Serena Giuntini et al.   INFECTION AND IMMUNITY

Complement-Mediated Bactericidal Activity of Anti-Factor H Binding Protein Monoclonal Antibodies against the Meningococcus Relies upon Blocking Factor H Binding

(2011) Serena Giuntini et al.   INFECTION AND IMMUNITY

A Meningococcal Factor H Binding Protein Mutant That Eliminates Factor H Binding Enhances Protective Antibody Responses to Vaccination

(2011) P. T. Beernink et al.   JOURNAL OF IMMUNOLOGY

Experimental Meningococcal Sepsis in Congenic Transgenic Mice Expressing Human Transferrin

(2011) Marek Szatanik et al.   PLoS One

Meningococcal carriage by age: a systematic review and meta-analysis

(2010) Hannah Christensen et al.   LANCET INFECTIOUS DISEASES

Carbohydrate vaccines: developing sweet solutions to sticky situations?

(2010) Rena D. Astronomo et al.   NATURE REVIEWS DRUG DISCOVERY

Generation of Human CEACAM1 Transgenic Mice and Binding of Neisseria Opa Protein to Their Neutrophils

(2010) Angel Gu et al.   PLoS One

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

(2010) J. Donnelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of Mucosal Immunity in the Human Upper Respiratory Tract to the Commensal Bacteria Neisseria lactamica but Not Pathogenic Neisseria meningitidis during the Peak Age of Nasopharyngeal Carriage

(2009) A. T. Vaughan et al.   JOURNAL OF IMMUNOLOGY

Relative importance of complement-mediated bactericidal and opsonic activity for protection against meningococcal disease

(2009) Dan M. Granoff   VACCINE

Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease

(2009) Carl E. Frasch et al.   VACCINE

Vaccine-Induced Opsonophagocytic Immunity to Neisseria meningitidis Group B

(2008) J. S. Plested et al.   Clinical and Vaccine Immunology

Meningococcal meningitis in Mali: a long-term study of persistence and spread

(2008) Solenne Philippon et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Impact of Meningococcal Serogroup C Conjugate Vaccines on Carriage and Herd Immunity

(2008) Martin C. J. Maiden et al.   JOURNAL OF INFECTIOUS DISEASES

Interleukin-17A Mediates Acquired Immunity to Pneumococcal Colonization

(2008) Ying-Jie Lu et al.   PLoS Pathogens