Article
Food Science & Technology
Zhongcan Peng, Yuming Wang, Jun He, Jia Zhang, Xuege Pan, Xiansheng Ye, Weiku Zhang, Jiekun Xu
Summary: Cornus officinalis fruits contain a variety of beneficial compounds with antioxidant and anti-inflammatory effects, making them a potential new source for functional foods.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Maria C. Tenuta, Brigitte Deguin, Monica R. Loizzo, Claire Cuyamendous, Marco Bonesi, Vincenzo Sicari, Lorenza Trabalzini, Anne-Claire Mitaine-Offer, Jianbo Xiao, Rosa Tundis
Summary: Cornus species, including Cornus mas and Cornus officinalis, are widely distributed in Europe, Africa, Asia, and America, and their edible fruits are known for their nutritional and medicinal values. These fruits contain various secondary metabolites with nutritional and functional properties. Although there is limited information available on the phytochemicals and biological activities of Cornus species, their potential for applications in the food industry and traditional medicine is of growing interest.
Article
Chemistry, Applied
Radoslaw Spychaj, Alicja Z. Kucharska, Antoni Szumny, Dominika Przybylska, Ewa Pejcz, Narcyz Piorecki
Summary: This study aimed to characterize the antioxidant potential, bioactive and volatile compounds of the stones from fruits of Cornus mas. Both fresh and roasted stones show a high antioxidant potential, which significantly depends on the cultivars. Roasted stones preserved a high percentage of the antioxidant activity of the non-roasted stones, and can be used as a coffee substitute or aromatic and bioactive additions to cereal coffees.
Article
Food Science & Technology
O. M. Szczepaniak, J. Kobus-Cisowska, K. Nowosad, K. Stuper-Szablewska, J. Markowska, P. Szulc
Summary: Cornelian cherry fruits are rich in antioxidants and biologically active compounds, with levels depending on maturity. The study aimed to analyze the relationship between color of Cornus mas cultivars and their content of key compounds. Genetic polymorphism analysis showed discrepancies between cultivars compared to chemical analyses. Different cultivars of Cornelian cherry adapt differently to the study, influencing fruit color, composition, and genetic relationships.
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2021)
Article
Food Science & Technology
Shucong Fan, Jianan Li, Xiaojuan Zhang, Dingqiao Xu, Xiang Liu, Alberto C. P. Dias, Xiaoying Zhang, Chen Chen
Summary: This study aimed to investigate the changes in chemical composition and biological activity of Cornus officinalis before and after simulated digestion in vitro. The results showed that the iridoid glycosides in C. officinalis were less stable than phenols during gastrointestinal digestion. After colonic fermentation simulation, iridoid glycosides were almost completely decomposed, while the content of phenolic compounds significantly increased. Additionally, the antioxidant activity significantly increased after colonic fermentation, and the alpha-amylase inhibitory activity in the small intestine also increased significantly.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Biochemistry & Molecular Biology
Xin Zhang, Hao Zhang, Pengfei Jiao, Mengrong Xia, Bo Tang
Summary: The present study focused on the preparation of bioactive peptides from Cornus officinalis proteins using compound enzymatic hydrolysis method. Response surface methodology coupled with Box-Behnken design was used to optimize the preparation process, and the results showed that the optimal conditions for peptide extraction were a pH value of 6.76, temperature of 48.84 degrees C, and enzyme amount of 0.19%. The prepared Cornus officinalis peptides exhibited significant antioxidant activity and promoted the proliferation of embryo fibroblast cells while repairing oxidative damage cells.
Article
Chemistry, Medicinal
Mara Aurori, Mihaela Niculae, Daniela Hanganu, Emoke Pall, Mihai Cenariu, Dan Cristian Vodnar, Andrea Bunea, Nicodim Fit, Sanda Andrei
Summary: This paper aims to characterize the phytochemical profile of Cornus mas L., evaluate its antioxidant, antimicrobial, and cytoprotective effects on renal cells. The results show that Cornus mas L. is rich in bioactive compounds and exhibits strong antioxidant and antimicrobial activities, as well as cytoprotective effects on renal cells.
Article
Nutrition & Dietetics
Mengyue Zhao, Weiwei Cao, Linlin Li, Aiqing Ren, Yuan Ang, Junliang Chen, Bhesh Bhandari, Zhe Wang, Xing Ren, Guangyue Ren, Xu Duan
Summary: Microcapsules of Cornus officinalis flavonoid were prepared using whey isolate protein and maltodextrin as wall materials, which showed high encapsulation efficiency and water solubility index, as well as small particle size and high antioxidant capacity.
FRONTIERS IN NUTRITION
(2022)
Article
Agricultural Engineering
Chang Ha Park, Ramaraj Sathasivam, Tae Jin Kim, Byung Bae Park, Jae Kwang Kim, Sang Un Park
Summary: Cornus officinalis is a valuable medicinal plant with various medicinal properties. This study analyzed the primary and secondary metabolites in different developmental stages of the fruit and found significant changes in their composition and content during fruit development.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Inorganic & Nuclear
Ramin Hosseini, Najmeh Mahdian, Zahra Yousefi
Summary: This study evaluated the effects of different doses of gamma radiation on various characteristics of Calendula officinalis, such as antioxidant activity, total phenolic compounds and flavonoid contents, antibacterial activity, and genomic alterations. The results showed significant differences in these features between the control samples and those exposed to gamma rays. Additionally, the study found that ISSR markers were more efficient than RAPD markers in detecting genetic variation.
APPLIED RADIATION AND ISOTOPES
(2023)
Article
Food Science & Technology
Mengyue Zhao, Linlin Li, Weiwei Cao, Zhe Wang, Qianqian Chu, Bhesh Bhandari, Guangyue Ren, Xu Duan
Summary: Spray drying, freeze-drying, and microwave freeze drying were used to encapsulate Cornus officinalis flavonoid (COF) using whey isolate protein and gum arabic as wall materials to improve its stability and solubility. The freeze-dried microparticles had the highest encapsulation efficiency and the smallest particle size. Spray-dried microparticles showed higher stability during storage, while the dissolution of microparticles dried by freeze-drying and microwave freeze drying was lower.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Plant Sciences
Jung-Ho Lee, Julia R. Austin, Joanna E. Burdette, Brian T. Murphy
Summary: The study found that a new secoiridoid, demethoxy-cornuside, along with other known secoiridoids isolated from the twigs of dogwood may potentiate progesterone signaling, affecting hormone-sensitive tissues.
JOURNAL OF NATURAL PRODUCTS
(2021)
Article
Materials Science, Paper & Wood
Xiaochen Yue, Zhaolin Li, Su Shiung Lam, Wan-Xi Peng, Yifeng He
Summary: This study analyzed the nutlet of Cornus officinalis using various techniques and found that its active ingredients have medicinal value and could be used as a substitute for the fruit. The residue left after extracting the active ingredients can be used as biomass liquid fuel, potentially replacing fossil fuels.
Review
Pharmacology & Pharmacy
Xue Gao, Yi Liu, Zhichao An, Jian Ni
Summary: Cornus officinalis Sieb. et Zucc., also known as Shanzhuyu, is a herb and food plant in east Asia with properties of tonifying the liver and kidney, and nourishing the essence in traditional Chinese medicine. Experimental studies have shown that its extract and active components have various pharmacological effects, but further clinical studies are needed to confirm their efficacy.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Nutrition & Dietetics
Mara Aurori, Sanda Andrei, Alexandra Iulia Dreanca, Andreea Georgiana Morohoschi, Mihaela Cotul, Mihaela Niculae, Monica Irina Nan, Andrei Razvan Codea, Adrian Florin Gal
Summary: This study aimed to investigate the nephroprotective properties of Cornus mas and Sorbus aucuparia fruits in an experimental model of nephrotoxicity. The results showed that these herbal extracts had significant renal tubular protective impact, but limited protection against renal glomeruli.
Article
Biochemistry & Molecular Biology
Olha Dzydzan, Iryna Brodyak, Paulina Strugala-Danak, Angelika Strach, Alicja Z. Kucharska, Janina Gabrielska, Natalia Sybirna
Summary: This study evaluated the in vitro bioactivity of red and yellow Cornelian cherry fruits' extracts and found that they exhibited diverse biological properties, including antioxidant activity, inhibitory activity against enzymes, and interactions with human serum albumin. These extracts could be exploited as a source of natural therapeutic agents.
Article
Biochemistry & Molecular Biology
Jolanta Piekarska, Marianna Szczypka, Michal Gorczykowski, Anna Sokol-Letowska, Alicja Z. Kucharska
Summary: Our experiment investigated the immunotropic activity of honeysuckle berry extract. The results showed that the extract stimulated the immune system and lymphocyte proliferation in mice infected with Trichinella spiralis. Additionally, the extract affected the dynamics of parasite expulsion from the intestines and prolonged the intestinal phase of the infection.
Article
Food Science & Technology
Beata Nowak, Agnieszka Matuszewska, Adam Szelag, Maciej Danielewski, Wojciech Dziewiszek, Anna Nikodem, Jaroslaw Filipiak, Diana Jedrzejuk, Marek Bolanowski, Alicja Z. Kucharska, Narcyz Piorecki, Tomasz Piasecki, Tomasz Sozanski
Summary: The aim of this study was to investigate the effects of cornelian cherry extract on metabolic changes induced by ovary removal, including bone loss, obesity development, adipokine imbalance, and oxidative stress. The results showed that cornelian cherry extract could improve weight gain, reduce visceral fat accumulation, restore adipokine balance, reduce oxidative stress, and prevent bone loss caused by ovary removal. This study is the first to demonstrate the bone-protective properties of cornelian cherry and its potential benefits for preventing cardiovascular diseases.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Nutrition & Dietetics
Malgorzata Malodobra-Mazur, Aneta Cierzniak, Martyna Ryba, Tomasz Sozanski, Narcyz Piorecki, Alicja Z. Kucharska
Summary: This study evaluated the effect of Cornus mas L. extract on insulin sensitivity in adipocytes. The results showed that the extract increased glucose uptake and insulin signaling gene expression, thus having a positive effect on cell metabolism.
Article
Biochemistry & Molecular Biology
Lukasz Lewandowski, Iwona Bednarz-Misa, Alicja Z. Kucharska, Agnieszka Kubiak, Patrycja Kasprzyk, Tomasz Sozanski, Dominika Przybylska, Narcyz Piorecki, Malgorzata Krzystek-Korpacka
Summary: This study investigates the cytotoxic effects of extracts from Cornus mas L. fruits on melanoma cell lines and finds that both extracts have cytotoxic effects, although the response of different cell lines varies. There is no evidence to suggest a difference in the magnitude of cytotoxicity between the two extracts.
Review
Food Science & Technology
Dominika Przybylska, A. Z. Kucharska, T. Sozanski
Summary: Iridoids are natural compounds widely found in plants. They possess diverse biological activities that can be used in disease prevention and treatment. Although scarce in edible fruits, iridoids do occur in some common and less common fruits. Iridoids can be applied in foods, drinks, and pharmaceuticals.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Uliana V. Semaniuk, Dmytro V. Gospodaryov, Olha M. Strilbytska, Alicja Z. Kucharska, Anna Sokol-Letowska, Nadia I. Burdyliuk, Kenneth B. Storey, Maria M. Bayliak, Oleh Lushchak
Summary: The study found that consumption of food supplemented with chili pepper powder can extend the lifespan of fruit flies, but this extension is not related to the antioxidant defense system. The effects of different concentrations of chili powder on fruit flies are gender-dependent.
Article
Chemistry, Applied
A. Kita, E. Rytel, J. Miedzianka, W. A. Turski, K. Wicha-Komsta, A. Z. Kucharska, T. Lenartowicz
Summary: This study investigated the content of biologically active compounds in new varieties of potatoes with purple and yellow flesh, harvested in different cultivation locations. Higher levels of kynurenic acid, phenolic acids, and amino acids were found in purple-fleshed potatoes compared to yellow-fleshed ones, while the total glycoalcaloids content was lower in purple-fleshed potatoes.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Eva Ivanisova, Marek Hornak, Matej Cech, Lubos Harangozo, Miroslava Kacaniova, Olga Grygorieva, Przemyslaw Lukasz Kowalczewski
Summary: The aim of this study was to analyze the antioxidant activity, polyphenol content, mineral composition, and antimicrobial activity of medicinal herbs commonly used in Slovakia. The results showed that the samples of Rosa canina and Fragaria vesca had the highest antioxidant activity. Fragaria vesca also had the highest polyphenol content, while Primula veris had the highest flavonoid content, and Thymus serpyllum had the highest phenolic acid content. The mineral composition varied among the different herbs, with Fragaria vesca and Thymus serpyllum having the highest levels of iron. The extracts of Equisetum arvense and Mentha piperita showed the strongest inhibitory activity against specific microorganisms.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Agnieszka Tajner-Czopek, Elzbieta Rytel, Agnieszka Kita, Anna Sokol-Letowska, Alicja Z. Kucharska
Summary: Potatoes with different flesh colours have varying amounts of health-promoting hydroxycinnamic acids, which are affected by thermal processing. This study aimed to investigate the impact of different stages of French fry production using potatoes of various flesh colours on the content and stability of hydroxycinnamic acids, as well as other antioxidant properties. The results demonstrated that the pre-drying and frying stages resulted in the greatest loss of hydroxycinnamic acids, and potatoes with coloured flesh, particularly purple, retained more of these acids. French fries made from coloured potatoes also had higher amounts of stable hydroxycinnamic acids compared to light-yellow fries.
Article
Biochemistry & Molecular Biology
Maciej Danielewski, Agnieszka Gomulkiewicz, Alicja Z. Kucharska, Agnieszka Matuszewska, Beata Nowak, Narcyz Piorecki, Malgorzata Trocha, Marta Szandruk-Bender, Paulina Jawien, Adam Szelag, Piotr Dziegiel, Tomasz Sozanski
Summary: This study aimed to determine the effect of Cornelian cherry extract on the markers important in the progress of inflammation and atherosclerotic lesion development. It found that the extract at a dose of 50 mg/kg bw resulted in a significant reduction in inflammation markers and serum levels related to atherosclerosis. The results suggest the potential usefulness of Cornelian cherry extract in preventing or treating atherosclerosis-related cardiovascular diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Eva Ivanisova, Matej Cech, Peter Hozlar, Grzegorz Zagula, Dorota Gumul, Olga Grygorieva, Agnieszka Makowska, Przemyslaw Lukasz Kowalczewski
Summary: This study reports on the nutritional composition, antioxidant properties, physical properties, and sensory profiles of bread enriched with black oat flour. Enriched breads showed higher content of protein, fat, crude fibre, ash, and beta-glucan compared to control bread. The enriched breads also exhibited higher amounts of manganese, iron, and calcium. The sensory properties of the enriched breads were evaluated as good. Consumption of enriched breads with black oat can increase the variety of bakery products in markets.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Uliana Semaniuk, Dmytro Gospodaryov, Olha M. Strilbytska, Alicja Z. Kucharska, Anna Sokot-Letowska, Nadia Burdyliuk, Kenneth B. Storey, Maria M. Bayliak, Oleh Lushchak
Summary: Chili powder, a widely used spice, has been found to improve healthspan in humans. A recent study investigated the effects of chili-supplemented food on fruit flies and found that it can extend lifespan, with the effect depending on the concentration of chili powder and gender. Consumption of chili-supplemented food also led to metabolic changes and increased resistance to cold shock in fruit flies.
Article
Biochemistry & Molecular Biology
Dorota Sosnowska, Anna Podsedek, Alicja Z. Kucharska
Summary: Phytocompounds in chokeberry fruit, particularly highly polymerized procyanidins, effectively inhibit pancreatic lipase activity. Fractionation and identification of phenolic compounds showed that low-molecular-weight phenolic compounds were less active. The most active fraction exhibited a mixed mode of pancreatic lipase inhibition and showed a cumulative effect with orlistat.
