Puerarin Attenuates Cadmium-Induced Neuronal Injury via Stimulating Cadmium Excretion, Inhibiting Oxidative Stress and Apoptosis

Yuzu and Hesperidin Ameliorate Blood-Brain Barrier Disruption during Hypoxia via Antioxidant Activity

(2020) Bo Kyung Lee et al.   Antioxidants

Alpha-lipoic acid protects against cadmium-induced neuronal injury by inhibiting the endoplasmic reticulum stress eIF2α-ATF4 pathway in rat cortical neurons in vitro and in vivo

(2019) Yan Yuan et al.   TOXICOLOGY

Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro

(2019) Amjad Khan et al.   Journal of Clinical Medicine

The anxiolytic-like effects of puerarin on an animal model of PTSD

(2019) Ai-shan Su et al.   BIOMEDICINE & PHARMACOTHERAPY

Puerarin alleviates streptozotocin (STZ)-induced osteoporosis in rats through suppressing inflammation and apoptosis via HDAC1/HDAC3 signaling

(2019) Chang-Jun Guo et al.   BIOMEDICINE & PHARMACOTHERAPY

Caspase/AIF/apoptosis pathway: a new target of puerarin for diabetes mellitus therapy

(2019) Tao Liang et al.   MOLECULAR BIOLOGY REPORTS

Effect of cadmium on osteoclast differentiation during bone injury in female mice

(2019) Shuangjiang He et al.   ENVIRONMENTAL TOXICOLOGY

Curcumin protects the testis against cadmium-induced histopathological damages and oxidative stress in mice

(2019) HR Momeni et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Astragaloside IV protects blood-brain barrier integrity from LPS-induced disruption via activating Nrf2 antioxidant signaling pathway in mice

(2018) Hongli Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway

(2018) Yan Yuan et al.   Scientific Reports

Long-term postmenopausal estrogen therapy may be associated with increased risk of breast cancer

(2018) Bruce Ettinger et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Effect of Puerarin Regulated mTOR Signaling Pathway in Experimental Liver Injury

(2018) Bu-Gao Zhou et al.   Frontiers in Pharmacology

Trehalose prevents cadmium-induced hepatotoxicity by blocking Nrf2 pathway, restoring autophagy and inhibiting apoptosis

(2018) Zhong-Gui Gong et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Pharmacokinetics and Tissue Distribution Kinetics of Puerarin in Rats Using Indirect Competitive ELISA

(2017) Hui Kong et al.   MOLECULES

Metabolomic analysis for combined hepatotoxicity of chlorpyrifos and cadmium in rats

(2017) Ming-Yuan Xu et al.   TOXICOLOGY

Treatment of cadmium-induced renal oxidative damage in rats by administration of alpha-lipoic acid

(2016) Tongwang Luo et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Protective Effects of Puerarin against Aβ 1–42-Induced Learning and Memory Impairments in Mice

(2016) Lidan Wu et al.   PLANTA MEDICA

Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats

(2016) Chin-Yi Cheng et al.   PLoS One

Targeting Oxidative Stress in Central Nervous System Disorders

(2016) Manisha Patel   TRENDS IN PHARMACOLOGICAL SCIENCES

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Gastrodin: An ancient Chinese herbal medicine as a source for anti-osteoporosis agents via reducing reactive oxygen species

(2015) Qiang Huang et al.   BONE

Puerarin Protects Human Neuroblastoma SH-SY5Y Cells against Glutamate-Induced Oxidative Stress and Mitochondrial Dysfunction

(2015) Xue Zhu et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway

(2015) Yan Yuan et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Protective Effect of l-Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway

(2015) Peiling Ben et al.   NEUROCHEMICAL RESEARCH

Oxidative stress and Parkinson’s disease

(2015) Javier Blesa et al.   Frontiers in Neuroanatomy

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

(2014) Li Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Puerarin Protects Hippocampal Neurons Against Cell Death in Pilocarpine-Induced Seizures Through Antioxidant and Anti-Apoptotic Mechanisms

(2014) Nanchang Xie et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice

(2013) Yanyan Zhou et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

(2013) Sujuan Chen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cadmium and Its Neurotoxic Effects

(2013) Bo Wang et al.   Oxidative Medicine and Cellular Longevity

Cadmium-Induced Apoptosis in Primary Rat Cerebral Cortical Neurons Culture Is Mediated by a Calcium Signaling Pathway

(2013) Yan Yuan et al.   PLoS One

Neuroprotective effects of puerarin against beta-amyloid-induced neurotoxicity in PC12 cells via a PI3K-dependent signaling pathway

(2011) Guihua Xing et al.   BRAIN RESEARCH BULLETIN

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

(2011) Ganta Chaitanya et al.   Cell Communication and Signaling

Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases

(2011) Ka H. Wong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

(2010) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke

(2009) Tiina Sairanen et al.   ACTA NEUROPATHOLOGICA

Protecting Mechanism of Puerarin on the Brain Neurocyte of Rat in Acute Local Ischemia Brain Injury and Local Cerebral Ischemia-reperfusion Injury

(2008) Hong-ping PAN et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN