Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation

MicroRNAs: From Mechanism to Organism

(2020) Philipp J. Dexheimer et al.   Frontiers in Cell and Developmental Biology

miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling

(2020) Marcus J. Hines et al.   Cell Reports

The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells

(2019) Wei Luo et al.   NATURE IMMUNOLOGY

The Complex Landscape of PTEN mRNA Regulation

(2019) Erin Sellars et al.   Cold Spring Harbor Perspectives in Medicine

Cell-type specific sequencing of microRNAs from complex animal tissues

(2018) Chiara Alberti et al.   NATURE METHODS

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK

(2017) Edina Schweighoffer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway

(2017) Xiao-yu Li et al.   Molecular Therapy-Nucleic Acids

MicroRNA-29 regulates high-glucose-induced apoptosis in human retinal pigment epithelial cells through PTEN

(2016) Xiaohui Lin et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development

(2016) Miriam Wöhner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of microRNA-141-3p in 5-fluorouracil and oxaliplatin chemo-resistance in esophageal cancer cells via regulation of PTEN

(2016) Ying-ying Jin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

(2016) Martina Minnich et al.   NATURE IMMUNOLOGY

The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

(2015) James Dooley et al.   DIABETES

Uridylation of RNA Hairpins by Tailor Confines the Emergence of MicroRNAs in Drosophila

(2015) Madalena M. Reimão-Pinto et al.   MOLECULAR CELL

MicroRNA-29A/PTEN pathway modulates neurite outgrowth in PC12 cells

(2015) H. Zou et al.   NEUROSCIENCE

Ensembl 2016

(2015) Andrew Yates et al.   NUCLEIC ACIDS RESEARCH

The B-cell antigen receptor integrates adaptive and innate immune signals

(2015) Kevin L. Otipoby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN

(2015) Juan Ji et al.   Scientific Reports

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

The Effect of Deleting p110  on the Phenotype and Function of PTEN-Deficient B Cells

(2014) M. L. Janas et al.   JOURNAL OF IMMUNOLOGY

Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation

(2013) Kyong-Rim Kieffer-Kwon et al.   CELL

Flexible Long-Range Loops in the VH Gene Region of the Igh Locus Facilitate the Generation of a Diverse Antibody Repertoire

(2013) Jasna Medvedovic et al.   IMMUNITY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis

(2012) Roger Revilla-i-Domingo et al.   EMBO JOURNAL

The Transcription Factors Egr2 and Egr3 Are Essential for the Control of Inflammation and Antigen-Induced Proliferation of B and T Cells

(2012) Suling Li et al.   IMMUNITY

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells

(2011) Shane McManus et al.   EMBO JOURNAL

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

(2011) Aikaterini S Papadopoulou et al.   NATURE IMMUNOLOGY

Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction

(2010) J. Rolf et al.   JOURNAL OF IMMUNOLOGY

Control systems and decision making for antibody production

(2010) Christopher C Goodnow et al.   NATURE IMMUNOLOGY

Akt1 and Akt2 promote peripheral B-cell maturation and survival

(2009) M. Calamito et al.   BLOOD

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

(2009) Thinh Huy Tran et al.   NATURE IMMUNOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

Instructive Role of the Transcription Factor E2A in Early B Lymphopoiesis and Germinal Center B Cell Development

(2008) Kyongrim Kwon et al.   IMMUNITY

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation

(2008) Hart S Dengler et al.   NATURE IMMUNOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY