Clonally expanded, GPR15-expressing pathogenic effector TH2 cells are associated with eosinophilic esophagitis

Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade

(2021) Christine Bangert et al.   Science Immunology

Helminth infections drive heterogeneity in human type 2 and regulatory cells

(2020) Karin de Ruiter et al.   Science Translational Medicine

Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening

(2020) Huang Huang et al.   NATURE BIOTECHNOLOGY

Ahr-Foxp3-RORγt axis controls gut homing of CD4+ T cells by regulating GPR15

(2020) Lifeng Xiong et al.   Science Immunology

Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies

(2020) Travis K. Hughes et al.   IMMUNITY

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

(2019) Maria Gutierrez-Arcelus et al.   Nature Communications

Eosinophilic esophagitis during sublingual and oral allergen immunotherapy

(2019) Joseph Cafone et al.   Current Opinion in Allergy and Clinical Immunology

Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis

(2019) Ting Wen et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells

(2019) Christopher Andrew Tibbitt et al.   IMMUNITY

TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures

(2019) Ang A. Tu et al.   NATURE IMMUNOLOGY

Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism

(2019) Hiroshi Kuwata et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Eosinophilic Esophagitis Reference Score Accurately Identifies Disease Activity and Treatment Effects in Children

(2018) Joshua B. Wechsler et al.   Clinical Gastroenterology and Hepatology

Epithelial origin of eosinophilic esophagitis

(2018) Mark Rochman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

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(2018) Jose Ordovas-Montanes et al.   NATURE

Utility of Gastric and Duodenal Biopsies During Follow-up Endoscopy in Children With Eosinophilic Esophagitis

(2017) Sunpreet Kaur et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

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(2017) L C Kottyan et al.   Mucosal Immunology

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(2017) Sara Aibar et al.   NATURE METHODS

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia

(2017) Thomas Suply et al.   Science Signaling

A phenotypically and functionally distinct human T H 2 cell subpopulation is associated with allergic disorders

(2017) Erik Wambre et al.   Science Translational Medicine

A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia

(2017) Thomas Suply et al.   Science Signaling

Eosinophilic esophagitis during peanut oral immunotherapy with omalizumab

(2017) Caitlin M. Burk et al.   Journal of Allergy and Clinical Immunology-In Practice

Elevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in mice

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(2016) Benjamin P. Davis et al.   Annual Review of Pathology-Mechanisms of Disease

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(2016) David A. Hill et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Leukocyte Trafficking to the Small Intestine and Colon

(2016) Aida Habtezion et al.   GASTROENTEROLOGY

Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human TH2 cell subpopulation with enhanced function

(2016) Alyssa Mitson-Salazar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB–induced Bcl-x L for inhibition of apoptosis

(2015) Christian Schwartz et al.   BLOOD

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Group 2 innate lymphocytes (ILC2) are enriched in active eosinophilic esophagitis

(2015) Taylor A. Doherty et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

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(2015) Glenn T. Furuta et al.   NEW ENGLAND JOURNAL OF MEDICINE

A draft network of ligand–receptor-mediated multicellular signalling in human

(2015) Jordan A. Ramilowski et al.   Nature Communications

p-STAT6, PU.1, and NF-κB are involved in allergen-induced late-phase airway inflammation in asthma patients

(2015) Deimante Hoppenot et al.   BMC Pulmonary Medicine

Relation between eosinophilic esophagitis and oral immunotherapy for food allergy: a systematic review with meta-analysis

(2014) Alfredo J. Lucendo et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing

(2014) J D Sherrill et al.   GENES AND IMMUNITY

IL-33 Markedly Activates Murine Eosinophils by an NF- B-Dependent Mechanism Differentially Dependent upon an IL-4-Driven Autoinflammatory Loop

(2013) C. Bouffi et al.   JOURNAL OF IMMUNOLOGY

Elimination Diet Effectively Treats Eosinophilic Esophagitis in Adults; Food Reintroduction Identifies Causative Factors

(2012) Nirmala Gonsalves et al.   GASTROENTEROLOGY

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Hierarchical IL-5 Expression Defines a Subpopulation of Highly Differentiated Human Th2 Cells

(2011) B. Upadhyaya et al.   JOURNAL OF IMMUNOLOGY

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells

(2011) Sabina A Islam et al.   NATURE IMMUNOLOGY