Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles

MSC-NTF (NurOwn®) exosomes: a novel therapeutic modality in the mouse LPS-induced ARDS model

(2021) Haggai Kaspi et al.   Stem Cell Research & Therapy

Role of miR‐466 in mesenchymal stromal cell derived extracellular vesicles treating inoculation pneumonia caused by multidrug‐resistant Pseudomonas aeruginosa

(2021) Meng‐meng Shi et al.   Clinical and Translational Medicine

Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin

(2020) J. J. Rouby et al.   INTENSIVE CARE MEDICINE

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

(2020) Phuong-Uyen C. Dinh et al.   Nature Communications

Exosomes Derived from Bone Marrow Mesenchymal Stem Cells as Treatment for Severe COVID-19

(2020) Vikram Sengupta et al.   STEM CELLS AND DEVELOPMENT

BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway

(2020) Bin Xu et al.   LIFE SCIENCES

Treatment of severe COVID-19 with human umbilical cord mesenchymal stem cells

(2020) Lei Shu et al.   Stem Cell Research & Therapy

Prophylactic treatment with MSC derived exosomes attenuates traumatic acute lung injury in rats

(2019) Qing-Chun Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A mesh nebulizer is more effective than jet nebulizer to nebulize bronchodilators during non-invasive ventilation of subjects with COPD: A randomized controlled trial with radiolabeled aerosols

(2019) Valdecir Castor Galindo-Filho et al.   RESPIRATORY MEDICINE

Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates

(2019) Sean D. McCarthy et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Inoculation Pneumonia Caused by Coagulase Negative Staphylococcus

(2019) Meng-meng Shi et al.   Frontiers in Microbiology

Exosomal miR-451 from human umbilical cord mesenchymal stem cells attenuates burn-induced acute lung injury

(2019) Ji-Song Liu et al.   Journal of the Chinese Medical Association

Acute Respiratory Distress Syndrome

(2018) Eddy Fan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model

(2018) Mahesh Khatri et al.   Stem Cell Research & Therapy

Therapeutic Implications of Human Umbilical Cord Mesenchymal Stromal Cells in Attenuating Influenza A(H5N1) Virus–Associated Acute Lung Injury

(2018) Hayley Loy et al.   JOURNAL OF INFECTIOUS DISEASES

Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severeE. colipneumonia

(2018) Jeonghyun Park et al.   THORAX

Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial

(2018) Michael A Matthay et al.   Lancet Respiratory Medicine

Acute Respiratory Distress Syndrome

(2017) B. Taylor Thompson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase II Multicenter, Randomized, Double-Blind Controlled Study of Efficacy and Safety of Umbilical Cord–Derived Mesenchymal Stromal Cells in the Prophylaxis of Chronic Graft-Versus-Host Disease After HLA-Haploidentical Stem-Cell Transplantation

(2016) Lei Gao et al.   JOURNAL OF CLINICAL ONCOLOGY

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

(2016) Julián Panés et al.   LANCET

Safety and Clinical Effects of Mesenchymal Stem Cells Secreting Neurotrophic Factor Transplantation in Patients With Amyotrophic Lateral Sclerosis

(2016) Panayiota Petrou et al.   JAMA Neurology

Therapeutic Effects of Human Mesenchymal Stem Cell–derived Microvesicles in Severe Pneumonia in Mice

(2015) Antoine Monsel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antibacterial effect of mesenchymal stem cells againstEscherichia coliis mediated by secretion of beta- defensin- 2 via toll- like receptor 4 signalling

(2015) Dong Kyung Sung et al.   CELLULAR MICROBIOLOGY

Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Pulmonary Infection Caused byPseudomonas aeruginosavia Inhibiting Overproduction of Prostaglandin E2

(2015) Yan-Xiong Mao et al.   STEM CELLS

Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat

(2015) J. Devaney et al.   THORAX

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial

(2015) Jennifer G Wilson et al.   Lancet Respiratory Medicine

Emerging inhalation aerosol devices and strategies: Where are we headed?

(2014) Qi (Tony) Zhou et al.   ADVANCED DRUG DELIVERY REVIEWS

Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study

(2014) Guoping Zheng et al.   RESPIRATORY RESEARCH

Therapeutic Effects of Human Mesenchymal Stem Cells inEx VivoHuman Lungs Injured with Live Bacteria

(2013) Jae W. Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mesenchymal stem cells enhance survival and bacterial clearance in murineEscherichia colipneumonia

(2012) Naveen Gupta et al.   THORAX

Exosomes/microvesicles as a mechanism of cell-to-cell communication

(2010) Giovanni Camussi et al.   KIDNEY INTERNATIONAL