Ultrasensitive detection of circulating tumour DNA via deep methylation sequencing aided by machine learning
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ultrasensitive detection of circulating tumour DNA via deep methylation sequencing aided by machine learning
Authors
Keywords
-
Journal
Nature Biomedical Engineering
Volume 5, Issue 6, Pages 586-599
Publisher
Springer Science and Business Media LLC
Online
2021-06-16
DOI
10.1038/s41551-021-00746-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- (2021) Ira W. Deveson et al. NATURE BIOTECHNOLOGY
- Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
- (2020) M.C. Liu et al. ANNALS OF ONCOLOGY
- Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
- (2020) Farshad Nassiri et al. NATURE MEDICINE
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers
- (2019) Chao Liu et al. Nature Biomedical Engineering
- Genome-wide cell-free DNA fragmentation in patients with cancer
- (2019) Stephen Cristiano et al. NATURE
- Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases
- (2019) Philipp Jurmeister et al. Science Translational Medicine
- Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer
- (2019) Bradon R. McDonald et al. Science Translational Medicine
- Unique genetic profiles from cerebrospinal fluid cell-free DNA in leptomeningeal metastases of EGFR-mutant non-small-cell lung cancer: a new medium of liquid biopsy
- (2018) Y S Li et al. ANNALS OF ONCOLOGY
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
- (2018) Katherine A. Hoadley et al. CELL
- CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data
- (2018) Wenyuan Li et al. NUCLEIC ACIDS RESEARCH
- Detection and localization of surgically resectable cancers with a multi-analyte blood test
- (2018) Joshua D. Cohen et al. SCIENCE
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Prevalence of clonal hematopoiesis of indeterminate potential (CHIP) measured by an ultra-sensitive sequencing assay: Exploratory analysis of the Circulating Cancer Genome Atlas (CCGA) study.
- (2018) Charles Swanton et al. JOURNAL OF CLINICAL ONCOLOGY
- Sensitive tumour detection and classification using plasma cell-free DNA methylomes
- (2018) Shu Yi Shen et al. NATURE
- Strategies for analyzing bisulfite sequencing data
- (2017) Katarzyna Wreczycka et al. JOURNAL OF BIOTECHNOLOGY
- Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
- (2017) Christopher Abbosh et al. NATURE
- Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA
- (2017) Shicheng Guo et al. NATURE GENETICS
- Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma
- (2017) Rui-hua Xu et al. NATURE MATERIALS
- The cancer epigenome: Concepts, challenges, and therapeutic opportunities
- (2017) Mark A. Dawson SCIENCE
- Direct detection of early-stage cancers using circulating tumor DNA
- (2017) Jillian Phallen et al. Science Translational Medicine
- Evaluating the necessity of PCR duplicate removal from next-generation sequencing data and a comparison of approaches
- (2016) Mark T. W. Ebbert et al. BMC BIOINFORMATICS
- Illumina error profiles: resolving fine-scale variation in metagenomic sequencing data
- (2016) Melanie Schirmer et al. BMC BIOINFORMATICS
- Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin
- (2016) Matthew W. Snyder et al. CELL
- Integrated digital error suppression for improved detection of circulating tumor DNA
- (2016) Aaron M Newman et al. NATURE BIOTECHNOLOGY
- SPlinted Ligation Adapter Tagging (SPLAT), a novel library preparation method for whole genome bisulphite sequencing
- (2016) Amanda Raine et al. NUCLEIC ACIDS RESEARCH
- Information recovery from low coverage whole-genome bisulfite sequencing
- (2016) Emanuele Libertini et al. Nature Communications
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
- (2015) Kun Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SAMBLASTER: fast duplicate marking and structural variant read extraction
- (2014) G. G. Faust et al. BIOINFORMATICS
- Impact of variance components on reliability of absolute quantification using digital PCR
- (2014) Bart KM Jacobs et al. BMC BIOINFORMATICS
- Sample size estimation in diagnostic test studies of biomedical informatics
- (2014) Karimollah Hajian-Tilaki JOURNAL OF BIOMEDICAL INFORMATICS
- Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing
- (2014) Hao Wu et al. NATURE BIOTECHNOLOGY
- TELP, a sensitive and versatile library construction method for next-generation sequencing
- (2014) Xu Peng et al. NUCLEIC ACIDS RESEARCH
- Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
- (2014) C. Bettegowda et al. Science Translational Medicine
- Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation
- (2013) Maura Costello et al. NUCLEIC ACIDS RESEARCH
- VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
- (2012) D. C. Koboldt et al. GENOME RESEARCH
- Analysing and interpreting DNA methylation data
- (2012) Christoph Bock NATURE REVIEWS GENETICS
- Linear amplification for deep sequencing
- (2011) Wieteke A M Hoeijmakers et al. Nature Protocols
- Principles and challenges of genome-wide DNA methylation analysis
- (2010) Peter W. Laird NATURE REVIEWS GENETICS
- Multiplex padlock targeted sequencing reveals human hypermutable CpG variations
- (2009) J. B. Li et al. GENOME RESEARCH
- Errors in the bisulfite conversion of DNA: modulating inappropriate- and failed-conversion frequencies
- (2008) D. P. Genereux et al. NUCLEIC ACIDS RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started