Galangin Attenuates Liver Injury, Oxidative Stress and Inflammation, and Upregulates Nrf2/HO-1 Signaling in Streptozotocin-Induced Diabetic Rats

Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats

(2021) Mohammad H. Abukhalil et al.   BIOMEDICINE & PHARMACOTHERAPY

Chicoric acid prevents methotrexate hepatotoxicity via attenuation of oxidative stress and inflammation and up-regulation of PPARγ and Nrf2/HO-1 signaling

(2020) Omnia E. Hussein et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Rumex dentatus L. phenolics ameliorate hyperglycemia by modulating hepatic key enzymes of carbohydrate metabolism, oxidative stress and PPARγ in diabetic rats

(2020) Rasha H. Elsayed et al.   FOOD AND CHEMICAL TOXICOLOGY

The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway

(2020) Liam Baird et al.   MOLECULAR AND CELLULAR BIOLOGY

Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway

(2020) Emad H. M. Hassanein et al.   Oxidative Medicine and Cellular Longevity

Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats

(2020) Mohammad H. Abukhalil et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK

(2019) Yazan Ranneh et al.   Nutrition & Metabolism

Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy

(2019) Osama Y. Althunibat et al.   LIFE SCIENCES

Discovery of Galangin as a Potential DPP-4 Inhibitor That Improves Insulin-Stimulated Skeletal Muscle Glucose Uptake: A Combinational Therapy for Diabetes

(2019) Poonam Kalhotra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity

(2019) Aladaileh et al.   Biomolecules

Consumption of Terpenoids-Rich Padina pavonia Extract Attenuates Hyperglycemia, Insulin Resistance and Oxidative Stress, and Upregulates PPARγ in a Rat Model of Type 2 Diabetes

(2019) Mousa O. Germoush et al.   Antioxidants

Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy

(2018) Amir M. Al Hroob et al.   BIOMEDICINE & PHARMACOTHERAPY

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

(2018) Loredana Salerno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-neuroinflammatory effects of galangin in LPS-stimulated BV-2 microglia through regulation of IL-1β production and the NF-κB signaling pathways

(2018) Mi Eun Kim et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia

(2018) Amal A. Aloud et al.   PHARMACEUTICAL BIOLOGY

Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats

(2018) Walaa G. Hozayen et al.   BIOMEDICINE & PHARMACOTHERAPY

Galangin and Pinocembrin from Propolis Ameliorate Insulin Resistance in HepG2 Cells via Regulating Akt/mTOR Signaling

(2018) Yinkang Liu et al.   Evidence-based Complementary and Alternative Medicine

Chicoric Acid Ameliorates Lipopolysaccharide-Induced Oxidative Stress via Promoting the Keap1/Nrf2 Transcriptional Signaling Pathway in BV-2 Microglial Cells and Mouse Brain

(2017) Qian Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oxidative stress-dependent contribution of HMGB1 to the interplay between apoptosis and autophagy in diabetic rat liver

(2017) Anja Petrović et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats

(2017) Nawal M. Al-Rasheed et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress in Metabolic Disorders and Drug-Induced Injury: The Potential Role of Nrf2 and PPARs Activators

(2017) Ayman M. Mahmoud et al.   Oxidative Medicine and Cellular Longevity

The Role of Nrf2 in Cardiovascular Function and Disease

(2017) Sandro Satta et al.   Oxidative Medicine and Cellular Longevity

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Galangin, a dietary flavonoid, improves antioxidant status and reduces hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats

(2016) Amal A. Aloud et al.   REDOX REPORT

Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats

(2016) Ayman Mahmoud et al.   Drug Design Development and Therapy

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol

(2015) Martina Gobec et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Molecular pathophysiology of hepatic glucose production

(2015) Kfir Sharabi et al.   MOLECULAR ASPECTS OF MEDICINE

Role of Nrf2 in chronic liver disease

(2014) Wei Tang   WORLD JOURNAL OF GASTROENTEROLOGY

Standards of Medical Care in Diabetes--2014

(2013)   DIABETES CARE

Transcription factor NRF2 protects mice against dietary iron-induced liver injury by preventing hepatocytic cell death

(2013) Sandro Silva-Gomes et al.   JOURNAL OF HEPATOLOGY

NRF2 Protection against Liver Injury Produced by Various Hepatotoxicants

(2013) Jie Liu et al.   Oxidative Medicine and Cellular Longevity

Screening for liver fibrosis by using FibroScan® and FibroTest in patients with diabetes

(2012) Victor de Lédinghen et al.   DIGESTIVE AND LIVER DISEASE

Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 diabetic rats

(2012) Ayman M. Mahmoud et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Role of IL-1β in type 2 diabetes

(2011) Charles A Dinarello et al.   Current Opinion in Endocrinology Diabetes and Obesity

Interleukin-1β May Mediate Insulin Resistance in Liver-Derived Cells in Response to Adipocyte Inflammation

(2010) Ori Nov et al.   ENDOCRINOLOGY

Dose-dependent effect of galangin on fructose-mediated insulin resistance and oxidative events in rat kidney

(2010) Allur S. Sivakumar et al.   REDOX REPORT

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

(2009) Hirokazu Sugimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Quercitrin, a bioflavonoid improves glucose homeostasis in streptozotocin-induced diabetic tissues by altering glycolytic and gluconeogenic enzymes

(2009) Ranganathan Babujanarthanam et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY