Smoking shifts human small airway epithelium club cells toward a lesser differentiated population

Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial Cells

(2021) Manish Bodas et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Using single-cell RNA sequencing to unravel cell lineage relationships in the respiratory tract

(2020) L.E. Zaragosi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

(2020) Katherine C. Goldfarbmuren et al.   Nature Communications

Single Cell Reconstruction of Human Basal Cell Diversity in Normal and IPF Lung

(2020) Gianni Carraro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Single-cell Atlas of the Human Healthy Airways

(2020) Marie Deprez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

(2020) Arun C. Habermann et al.   Science Advances

Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

(2020) Kenichi Okuda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Structure and Mechanisms of F-Type ATP Synthases

(2019) Werner Kühlbrandt   Annual Review of Biochemistry

Evolving complexity of MIF signaling

(2019) Stanislovas S. Jankauskas et al.   CELLULAR SIGNALLING

Lactate Dehydrogenases as Metabolic Links between Tumor and Stroma in the Tumor Microenvironment

(2019) Deepshikha Mishra et al.   Cancers

Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures

(2019) Sandra Ruiz García et al.   DEVELOPMENT

Ontogeny and Biology of Human Small Airway Epithelial Club Cells

(2018) Wu-Lin Zuo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

Comparative biochemistry of cytochrome c oxidase in animals

(2018) A.G. Little et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

(2018) Ana Luisa Cardoso et al.   AGEING RESEARCH REVIEWS

Allergic inflammatory memory in human respiratory epithelial progenitor cells

(2018) Jose Ordovas-Montanes et al.   NATURE

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

(2018) Paul A Reyfman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

p62/ SQSTM 1: ‘Jack of all trades’ in health and cancer

(2018) Pablo Sánchez‐Martín et al.   FEBS Journal

Alpha-Enolase i ENO1 i a potential target in novel immunotherapies

(2017) Francesco Novelli   Frontiers in Bioscience-Landmark

Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression

(2017) Zhi Tian et al.   Scientific Reports

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

(2016) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The place of inhaled corticosteroids in the treatment of chronic obstructive pulmonary disease: a narrative review

(2016) Pavlina A. Andreeva-Gateva et al.   POSTGRADUATE MEDICINE

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Exacerbation of Chronic Obstructive Pulmonary Disease

(2015) Xianghui Zhou et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Supplementing Defect in Club Cell Secretory Protein Attenuates Airway Inflammation in COPD

(2015) Anne Sophie Gamez et al.   CHEST

Protective role for club cell secretory protein-16 (CC16) in the development of COPD

(2015) Maria E. Laucho-Contreras et al.   EUROPEAN RESPIRATORY JOURNAL

Polymeric Immunoglobulin Receptor Down-regulation in Chronic Obstructive Pulmonary Disease. Persistence in the Cultured Epithelium and Role of Transforming Growth Factor-β

(2014) Sophie T. Gohy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Club cell 10-kDa protein attenuates airway mucus hypersecretion and inflammation

(2014) E. Tokita et al.   EUROPEAN RESPIRATORY JOURNAL

Harnessing the potential of lung stem cells for regenerative medicine

(2014) Jonathan L. McQualter et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Club Cell Protein 16 and Disease Progression in Chronic Obstructive Pulmonary Disease

(2013) Hye Yun Park et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fatty aldehyde and fatty alcohol metabolism: Review and importance for epidermal structure and function

(2013) William B. Rizzo   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

(2012) Andrew McDavid et al.   BIOINFORMATICS

Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism

(2012) Carolyn Ritterson Lew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Human Airway Epithelial Basal Cell Transcriptome

(2011) Neil R. Hackett et al.   PLoS One

Network Inference Algorithms Elucidate Nrf2 Regulation of Mouse Lung Oxidative Stress

(2011) Ronald C. Taylor et al.   PLoS Computational Biology

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis

(2010) Alexander Arlt et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

Clara cell: Progenitor for the bronchiolar epithelium

(2009) Susan D. Reynolds et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents

(2009) Songcang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2009) Ralf-Harto Hubner et al.   MOLECULAR MEDICINE

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tumor antigen epcam: tetraspanins and the tight junction protein claudin-7, new partners, new functions

(2008) Francois Le Naour   Frontiers in Bioscience-Landmark

Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort

(2008) D A Lomas et al.   THORAX