Film-Forming Systems for Dermal Drug Delivery

Film-forming formulations represent a novel form of sustained release dermatic products. They are applied to the skin as a liquid or semi-solid preparation. By evaporation of the volatile solvent on the skin, the polymer contained in the formulation forms a solid film. Various film-forming formulations were tested for their water and abrasion resistance and compared with conventional semi-solid formulations. Penetration and permeation studies of the formulations indicate a potential utility as transdermal therapeutic systems. They can be used as an alternative to patch systems to administer a variety of drugs in a topical way and may provide sustained release characteristics.

Automated summary

Film-forming formulations are a novel form of sustained release dermatic products that create a solid film on the skin and can serve as an alternative to patch systems for transdermal drug delivery, offering sustained release characteristics. Penetration and permeation studies show their potential utility as transdermal therapeutic systems.