A Drug Repositioning Approach Identifies a Combination of Compounds as a Potential Regimen for Chronic Lymphocytic Leukemia Treatment

Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP

(2018) Rakesh K. Singh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Review of Drug Repositioning Approaches and Resources

(2018) Hanqing Xue et al.   International Journal of Biological Sciences

Combination therapy in combating cancer

(2017) Reza Bayat Mokhtari et al.   Oncotarget

Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics

(2017) J. Javier Hernandez et al.   Frontiers in Oncology

Hydrogen (H2) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways

(2016) Yaxing Zhang et al.   Frontiers in Pharmacology

Mechanisms of isoproterenol-induced cardiac mitochondrial damage: protective actions of melatonin

(2015) Debasri Mukherjee et al.   JOURNAL OF PINEAL RESEARCH

Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

(2015) A Eriksson et al.   Blood Cancer Journal

Deficiency in Either 4E-BP1 or 4E-BP2 Augments Innate Antiviral Immune Responses

(2014) Atef Nehdi et al.   PLoS One

The Clinical Relevance of Cancer Cell Lines

(2013) J.-P. Gillet et al.   JNCI-Journal of the National Cancer Institute

Technologies for deriving primary tumor cells for use in personalized cancer therapy

(2013) Abhisek Mitra et al.   TRENDS IN BIOTECHNOLOGY

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+Biosynthesis, in Human Cancer Cells

(2012) Bo Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of intracellular ATP to cisplatin resistance of tumor cells

(2012) Verena Schneider et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The beta2-adrenergic receptor on T and B lymphocytes: Do we understand it yet?

(2011) Virginia M. Sanders   BRAIN BEHAVIOR AND IMMUNITY

Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells

(2011) Y. Zhou et al.   CANCER RESEARCH

Chemoprevention: First line of defence

(2011) Lauren Gravitz   NATURE

Efficacy of anti-cancer agents in cell lines versus human primary tumour tissue

(2010) Ian A Cree et al.   CURRENT OPINION IN PHARMACOLOGY

Chemosensitivity and chemoresistance testing in ovarian cancer

(2009) Ian A Cree   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence

(2009) Oluwakemi Obajimi et al.   PROSTATE