Journal
ACS SENSORS
Volume 6, Issue 8, Pages 2787-2801Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acssensors.1c01133
Keywords
health monitoring; wearable sensors; epidermal microfluidics; lab-on-chip; flexible electronics; biosensors; sweat analysis; eccrine sweat
Funding
- Querrey Simpson Institute for Bioelectronics at Northwestern University
- National Institute on Aging of the National Institutes of Health [R43AG067835]
- National Institute of General Medical Sciences of the National Institutes of Health [P20GM113134]
- Hawai'i Community Foundation (Robert C. Perry Fund)
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Wearable systems with integrated colorimetric assays, microfluidic channels, and electrochemical sensors provide powerful capabilities for noninvasive, real-time sweat analysis. Recent progress in the development of wearable sensors allows for personalized assessment with precise sampling and real-time analysis, enabling broad deployment in field studies and clinical trials.
Skin-interfaced wearable systems with integrated colorimetric assays, microfluidic channels, and electrochemical sensors offer powerful capabilities for noninvasive, real-time sweat analysis. This Perspective details recent progress in the development and translation of novel wearable sensors for personalized assessment of sweat dynamics and biomarkers, with precise sampling and real-time analysis. Sensor accuracy, system ruggedness, and large-scale deployment in remote environments represent key opportunity areas, enabling broad deployment in the context of field studies, clinical trials, and recent commercialization. On-body measurements in these contexts show good agreement compared to conventional laboratory-based sweat analysis approaches. These device demonstrations highlight the utility of biochemical sensing platforms for personalized assessment of performance, wellness, and health across a broad range of applications.
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