Epigenetics in Kawasaki Disease

Hypomethylation of C1q/tumor necrosis factor-related protein-1 promoter region in whole blood and risks for coronary artery aneurysms in Kawasaki disease

(2020) Haobo Weng et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Epigenetic Regulation of Macrophage Marker Expression Profiles in Kawasaki Disease

(2020) Mindy Ming-Huey Guo et al.   Frontiers in Pediatrics

Evaluating the added predictive ability of MMP-9 in serum for Kawasaki disease with coronary artery lesions

(2020) Lixia Wang et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Circulating microRNAs differentiate Kawasaki Disease from infectious febrile illnesses in childhood

(2020) Pei-Ni Jone et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease

(2019) Tai-Ming Ko et al.   Scientific Reports

Increase expression of CD177 in Kawasaki disease

(2019) Ying-Hsien Huang et al.   Pediatric Rheumatology

The therapeutic role of long non-coding RNAs in human diseases: A focus on the recent insights into autophagy

(2019) Samira Barangi et al.   PHARMACOLOGICAL RESEARCH

Kawasaki Disease: The Role of Immune Complexes Revisited

(2019) Stephanie Menikou et al.   Frontiers in Immunology

Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools

(2019) Sanae Ben Mkaddem et al.   Frontiers in Immunology

MiR-222-3p in Platelets Serves as a Distinguishing Marker for Early Recognition of Kawasaki Disease

(2019) Bo Wang et al.   Frontiers in Pediatrics

Up‐regulation of miR‐27a promotes monocyte‐mediated inflammatory responses in Kawasaki disease by inhibiting function of B10 cells

(2019) Ying Luo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of increased expression of activating Fc receptors and novel findings regarding distinct IgE and IgM receptors in Kawasaki disease

(2019) Ling-Sai Chang et al.   PEDIATRIC RESEARCH

miR‑186, a serum microRNA, induces endothelial cell apoptosis by targeting SMAD6 in Kawasaki disease

(2018) Rongzhou Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

HAMP promoter hypomethylation and increased hepcidin levels as biomarkers for Kawasaki disease

(2018) Ying-Hsien Huang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Epidemiological observations of Kawasaki disease in Japan, 2013-2014

(2018) Nobuko Makino et al.   PEDIATRICS INTERNATIONAL

Serum exosomal miR‑328, miR‑575, miR‑134 and miR‑671‑5p as potential biomarkers for the diagnosis of Kawasaki disease and the prediction of therapeutic outcomes of intravenous immunoglobulin therapy

(2018) Xiaofei Zhang et al.   Experimental and Therapeutic Medicine

Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

(2018) Yifei Miao et al.   Nature Communications

Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease

(2018) Ying-Hsien Huang et al.   Oncotarget

The human blood DNA methylome identifies crucial role of β-catenin in the pathogenesis of Kawasaki disease

(2018) Kuang-Den Chen et al.   Oncotarget

Predictors of intravenous immunoglobulin resistance and coronary artery aneurysm in patients with Kawasaki disease

(2018) Nattika Chantasiriwan et al.   Paediatrics and International Child Health

miR-27b Suppresses Endothelial Cell Proliferation and Migration by Targeting Smad7 in Kawasaki Disease

(2018) Xing Rong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-145-5p and microRNA-320a encapsulated in endothelial microparticles contribute to the progression of vasculitis in acute Kawasaki Disease

(2018) Hideyuki Nakaoka et al.   Scientific Reports

Multiomics analyses identified epigenetic modulation of the S100A gene family in Kawasaki disease and their significant involvement in neutrophil transendothelial migration

(2018) Lien-Hung Huang et al.   Clinical Epigenetics

The Epidemiology and Pathogenesis of Kawasaki Disease

(2018) Anne H. Rowley et al.   Frontiers in Pediatrics

The NLRC4 Inflammasome

(2017) Joseph A. Duncan et al.   IMMUNOLOGICAL REVIEWS

Identification of differentially expressed microRNAs in acute Kawasaki disease

(2017) Ye Chen et al.   Molecular Medicine Reports

An atlas of human long non-coding RNAs with accurate 5′ ends

(2017) Chung-Chau Hon et al.   NATURE

Epigenetic hypomethylation and upregulation of matrix metalloproteinase 9 in Kawasaki disease

(2017) Ho-Chang Kuo et al.   Oncotarget

Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease

(2017) Ying-Hsien Huang et al.   Oncotarget

Sets of serum exosomal microRNAs as candidate diagnostic biomarkers for Kawasaki disease

(2017) Hong-Ling Jia et al.   Scientific Reports

Serum miR-200c and miR-371-5p as the Useful Diagnostic Biomarkers and Therapeutic Targets in Kawasaki Disease

(2017) Wei Zhang et al.   Biomed Research International

Bone Marrow–Derived MicroRNA‐223 Works as an Endocrine Genetic Signal in Vascular Endothelial Cells and Participates in Vascular Injury From Kawasaki Disease

(2017) Maoping Chu et al.   Journal of the American Heart Association

A plasma mir-125a-5p as a novel biomarker for Kawasaki disease and induces apoptosis in HUVECs

(2017) Zhuoying Li et al.   PLoS One

Major methylation alterations on the CpG markers of inflammatory immune associated genes after IVIG treatment in Kawasaki disease

(2016) Sung-Chou Li et al.   BMC Medical Genomics

TNF-α induces vascular endothelial cells apoptosis through overexpressing pregnancy induced noncoding RNA in Kawasaki disease model

(2016) Chunming Jiang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Next-generation sequencing identifies micro-RNA–based biomarker panel for Kawasaki disease

(2016) Ho-Chang Kuo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Kawasaki Disease

(2016) Jane W. Newburger et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MicroRNA-93 may control vascular endothelial growth factor A in circulating peripheral blood mononuclear cells in acute Kawasaki disease

(2016) Kazuyoshi Saito et al.   PEDIATRIC RESEARCH

The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease

(2016) Ling-Sai Chang et al.   Oncotarget

Th17- and Treg-related cytokine and mRNA expression are associated with acute and resolving Kawasaki disease

(2015) M. M.-H. Guo et al.   ALLERGY

Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis

(2015) Y. Motomura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hepcidin-ferroportin axis controls toll-like receptor 4 dependent macrophage inflammatory responses in human atherosclerotic plaques

(2015) Anwer Habib et al.   ATHEROSCLEROSIS

CXCL10/IP-10 Is a Biomarker and Mediator for Kawasaki Disease

(2015) T.-M. Ko et al.   CIRCULATION RESEARCH

Epidemiologic features of Kawasaki disease in acute stages in Taiwan, 1997–2010: Effect of different case definitions in claims data analysis

(2015) Ming-Chih Lin et al.   Journal of the Chinese Medical Association

Systematic Confirmation Study of GWAS-Identified Genetic Variants for Kawasaki Disease in A Chinese Population

(2015) Jiao Lou et al.   Scientific Reports

Identification of an Association Between Genomic Hypomethylation ofFCGR2Aand Susceptibility to Kawasaki Disease and Intravenous Immunoglobulin Resistance by DNA Methylation Array

(2015) Ho-Chang Kuo et al.   Arthritis & Rheumatology

Regulatory T cell microRNA expression changes in children with acute Kawasaki disease

(2014) F.-F. Ni et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Macrophage-like U937 cells recognize collagen fibrils with strain-induced discrete plasticity damage

(2014) Samuel P. Veres et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

A Study of Cardiovascular miRNA Biomarkers for Kawasaki Disease

(2014) Anne H. Rowley et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Lack of CD4+CD25+FOXP3+ regulatory T cells is associated with resistance to intravenous immunoglobulin therapy in patients with Kawasaki disease

(2013) Yu Hirabayashi et al.   EUROPEAN JOURNAL OF PEDIATRICS

Elevated Serum Level of MicroRNA (miRNA)-200c and miRNA-371-5p in Children with Kawasaki Disease

(2013) Ki Wook Yun et al.   PEDIATRIC CARDIOLOGY

Epidemiologic Features of Kawasaki Disease in South Korea

(2013) Gi Beom Kim et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

FcγR gene copy number in Kawasaki disease and intravenous immunoglobulin treatment response

(2013) Robert Makowsky et al.   Pharmacogenetics and Genomics

Differential Expression of miR-145 in Children with Kawasaki Disease

(2013) Chisato Shimizu et al.   PLoS One

Replication and Meta-Analysis of GWAS Identified Susceptibility Loci in Kawasaki Disease Confirm the Importance of B Lymphoid Tyrosine Kinase (BLK) in Disease Susceptibility

(2013) Chia-Jung Chang et al.   PLoS One

The long noncoding RNA THRIL regulates TNF  expression through its interaction with hnRNPL

(2013) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and function of long non-coding RNA

(2013) Carl Ernst et al.   Frontiers in Cellular Neuroscience

Evaluation of intravenous immunoglobulin resistance and coronary artery lesions in relation to Th1/Th2 cytokine profiles in patients with Kawasaki disease

(2012) Yujia Wang et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1β Is Crucial for the Induction of Coronary Artery Inflammation in a Mouse Model of Kawasaki Disease

(2012) Youngho Lee et al.   CIRCULATION

Circulating MicroRNAs

(2012) Esther E. Creemers et al.   CIRCULATION RESEARCH

Role of Activating Fc γ R Gene Polymorphisms in Kawasaki Disease Susceptibility and Intravenous Immunoglobulin Response

(2012) Sadeep Shrestha et al.   Circulation-Cardiovascular Genetics

The role of TGF-β and myofibroblasts in the arteritis of Kawasaki disease

(2012) Chisato Shimizu et al.   HUMAN PATHOLOGY

Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis

(2012) Yi-Ching Lee et al.   NATURE GENETICS

A genome-wide association study identifies three new risk loci for Kawasaki disease

(2012) Yoshihiro Onouchi et al.   NATURE GENETICS

Integrins α4 and αM, collagen1A1 and matrix metalloproteinase 7 are upregulated in acute Kawasaki disease vasculopathy

(2012) Rebecca Reindel et al.   PEDIATRIC RESEARCH

Augmented TLR2 Expression on Monocytes in both Human Kawasaki Disease and a Mouse Model of Coronary Arteritis

(2012) I-Chun Lin et al.   PLoS One

Nod1 Ligands Induce Site-Specific Vascular Inflammation

(2011) Hisanori Nishio et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition

(2011) A Magenta et al.   CELL DEATH AND DIFFERENTIATION

Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair

(2011) Jinzhu Duan et al.   EMBO JOURNAL

MicroRNAs and epigenetics

(2011) Fumiaki Sato et al.   FEBS Journal

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Identification of Novel Susceptibility Loci for Kawasaki Disease in a Han Chinese Population by a Genome-Wide Association Study

(2011) Fuu-Jen Tsai et al.   PLoS One

MicroRNA, Emerging Role as a Biomarker of Heart Failure

(2010) Tsuneaki Kawashima et al.   CIRCULATION JOURNAL

The T helper type 17/regulatory T cell imbalance in patients with acute Kawasaki disease

(2010) S. Jia et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Circulating microRNAs: Association with disease and potential use as biomarkers

(2010) Glen Reid et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Epigenetics and gene expression

(2010) E R Gibney et al.   HEREDITY

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

MicroRNA is a New Diagnostic and Therapeutic Target for Cardiovascular Disease and Regenerative Medicine

(2009) Ruri Kaneda et al.   CIRCULATION JOURNAL

MicroRNA identification in plasma and serum: a new tool to diagnose and monitor diseases

(2009) Maria Angelica Cortez et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Matrix metalloproteinase 9 activity leads to elastin breakdown in an animal model of Kawasaki disease

(2008) Andrew C. Lau et al.   ARTHRITIS AND RHEUMATISM

Biological principles of microRNA-mediated regulation: shared themes amid diversity

(2008) Alex S. Flynt et al.   NATURE REVIEWS GENETICS

High mobility group box 1 (HMGB1) and macrophage migration inhibitory factor (MIF) in Kawasaki disease

(2008) T. Hoshina et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY