The chromosome-level reference genome of Coptis chinensis provides insights into genomic evolution and berberine biosynthesis

Genome and transcriptome of Papaver somniferum Chinese landrace CHM indicates that massive genome expansion contributes to high benzylisoquinoline alkaloid biosynthesis

(2021) Li Pei et al.   Horticulture Research

A chromosome-scale reference genome of Aquilegia oxysepala var. kansuensis

(2020) Jinghe Xie et al.   Horticulture Research

De novo assembly of a wild pear ( Pyrus betuleafolia ) genome

(2019) Xingguang Dong et al.   PLANT BIOTECHNOLOGY JOURNAL

Composition and diversity of rhizosphere fungal community in Coptis chinensis Franch. continuous cropping fields

(2018) Xuhong Song et al.   PLoS One

Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species

(2018) Si-Mei He et al.   Frontiers in Plant Science

The opium poppy genome and morphinan production

(2018) Li Guo et al.   SCIENCE

The Aquilegia genome provides insight into adaptive radiation and reveals an extraordinarily polymorphic chromosome with a unique history

(2018) Danièle L Filiault et al.   eLife

Non-coding RNAs and Berberine: A new mechanism of its anti-diabetic activities

(2017) Wenguang Chang   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways

(2017) Han-bin Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism

(2017) Xiubin Liu et al.   Molecular Plant

The Tea Tree Genome Provides Insights into Tea Flavor and Independent Evolution of Caffeine Biosynthesis

(2017) En-Hua Xia et al.   Molecular Plant

Identification of candidate genes involved in isoquinoline alkaloids biosynthesis in Dactylicapnos scandens by transcriptome analysis

(2017) Si Mei He et al.   Scientific Reports

Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells

(2016) Jiasi Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A hybrid approach for de novo human genome sequence assembly and phasing

(2016) Yulia Mostovoy et al.   NATURE METHODS

Phased diploid genome assembly with single-molecule real-time sequencing

(2016) Chen-Shan Chin et al.   NATURE METHODS

BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs

(2015) Felipe A. Simão et al.   BIOINFORMATICS

The pineapple genome and the evolution of CAM photosynthesis

(2015) Ray Ming et al.   NATURE GENETICS

Alkaloids from Coptis chinensis root promote glucose uptake in C2C12 myotubes

(2014) Te-Chun Yang et al.   FITOTERAPIA

Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement

(2014) Bruce J. Walker et al.   PLoS One

Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data

(2013) Chen-Shan Chin et al.   NATURE METHODS

New enantiomeric isoquinoline alkaloids from Coptis chinensis

(2013) Lei Wang et al.   Phytochemistry Letters

Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres

(2012) Andrew H. Paterson et al.   NATURE

MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity

(2012) Y. Wang et al.   NUCLEIC ACIDS RESEARCH

A fast, lock-free approach for efficient parallel counting of occurrences of k-mers

(2011) Guillaume Marçais et al.   BIOINFORMATICS

Berberine as a Promising Safe Anti-Cancer Agent- Is there a Role for Mitochondria?

(2011) Catia V. Diogo et al.   CURRENT DRUG TARGETS

Anti-ultraviolet radiation effects of Coptis chinensis and Phellodendron amurense glycans by immunomodulating and inhibiting oxidative injury

(2011) Hui Yan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Probabilistic modeling of Hi-C contact maps eliminates systematic biases to characterize global chromosomal architecture

(2011) Eitan Yaffe et al.   NATURE GENETICS

KNApSAcK Family Databases: Integrated Metabolite–Plant Species Databases for Multifaceted Plant Research

(2011) Farit Mochamad Afendi et al.   PLANT AND CELL PHYSIOLOGY

Effects and Action Mechanisms of Berberine and Rhizoma coptidis on Gut Microbes and Obesity in High-Fat Diet-Fed C57BL/6J Mice

(2011) Weidong Xie et al.   PLoS One

Genome-wide association studies of 14 agronomic traits in rice landraces

(2010) Xuehui Huang et al.   NATURE GENETICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments

(2008) Brian J Haas et al.   GENOME BIOLOGY

Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry

(2007) Dan Yan et al.