Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus

Spexin as an anxiety regulator in mouse hippocampus: Mechanisms for transcriptional regulation of spexin gene expression by corticotropin releasing factor

(2020) Min Zhuang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Spexin and a Novel Cichlid-Specific Spexin Paralog Both Inhibit FSH and LH Through a Specific Galanin Receptor (Galr2b) in Tilapia

(2020) Yaron Cohen et al.   Frontiers in Endocrinology

Spexin/NPQ Induces fos and Produces Antinociceptive Effect against Inflammatory Pain in the Mouse Model

(2019) Shuang-Yu Lv et al.   AMERICAN JOURNAL OF PATHOLOGY

Serum levels of spexin are increased in the third trimester pregnancy with gestational diabetes mellitus

(2019) Murat Akbas et al.   GYNECOLOGICAL ENDOCRINOLOGY

The Role of Ghrelin in Regulating Synaptic Function and Plasticity of Feeding-Associated Circuits

(2019) Débora Serrenho et al.   Frontiers in Cellular Neuroscience

Spexin-Based Galanin Receptor Type 2 Agonist for Comorbid Mood Disorders and Abnormal Body Weight

(2019) Seongsik Yun et al.   Frontiers in Neuroscience

Emerging Roles of NPQ/Spexin in Physiology and Pathology

(2019) Shuang-Yu Lv et al.   Frontiers in Pharmacology

Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus

(2019) Este Leidmaa et al.   Acta Physiologica

Evolution of Structural and Functional Diversity of Spexin in Mammalian and Non-mammalian Vertebrate Species

(2019) Chor Hong Lim et al.   Frontiers in Endocrinology

Longitudinal study on novel neuropeptides phoenixin, spexin and kisspeptin in adolescent inpatients with anorexia nervosa – association with psychiatric symptoms

(2019) Artur Pałasz et al.   NUTRITIONAL NEUROSCIENCE

Spexin in the half-smooth tongue sole (Cynoglossus semilaevis): molecular cloning, expression profiles, and physiological effects

(2018) Shengpeng Wang et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Molecular cloning, characterization and expression analysis of spexin in spotted scat ( Scatophagus argus )

(2018) Si-ping Deng et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Spexin as a neuroendocrine signal with emerging functions

(2018) Ani Ma et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa

(2018) Artur Pałasz et al.   NEUROCHEMISTRY INTERNATIONAL

Spexin Modulates Functions of Rat Endocrine Pancreatic Cells

(2018) Maciej Sassek et al.   PANCREAS

Roux en-Y gastric bypass surgery in youth with severe obesity: 1-year longitudinal changes in spexin

(2018) Seema Kumar et al.   Surgery for Obesity and Related Diseases

Spexin Acts as Novel Regulator for Bile Acid Synthesis

(2018) Cheng-yuan Lin et al.   Frontiers in Physiology

Spexin: A novel regulator of adipogenesis and fat tissue metabolism

(2018) Pawel A. Kolodziejski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Spexin Levels Are Associated with Metabolic Syndrome Components

(2018) Nasser M. Al-Daghri et al.   DISEASE MARKERS

Decreased Spexin Levels in Patients with Type 1 and Type 2 Diabetes

(2018) Anara Karaca et al.   MEDICAL PRINCIPLES AND PRACTICE

Spexin Suppress Food Intake in Zebrafish: Evidence from Gene Knockout Study

(2017) Binbin Zheng et al.   Scientific Reports

Nonalcoholic Fatty Liver Disease

(2016) Paul D. Berk et al.   Clinics in Liver Disease

Molecular cloning and functional characterization of spexin in orange-spotted grouper ( Epinephelus coioides )

(2016) Shuisheng Li et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Decreased Circulating Levels of Spexin in Obese Children

(2016) Seema Kumar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Escitalopram affects spexin expression in the rat hypothalamus, hippocampus and striatum

(2016) Artur Pałasz et al.   Pharmacological Reports

Regulation of Hepatocellular Fatty Acid Uptake in Mouse Models of Fatty Liver Disease with and without Functional Leptin Signaling: Roles of NfKB and SREBP-1C and the Effects of Spexin

(2016) Jasmine Ge et al.   SEMINARS IN LIVER DISEASE

The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge

(2016) Helene Volkoff   Frontiers in Neuroscience

Development of Spexin-based Human Galanin Receptor Type II-Specific Agonists with Increased Stability in Serum and Anxiolytic Effect in Mice

(2016) Arfaxad Reyes-Alcaraz et al.   Scientific Reports

Ya-fish (Schizothorax prenanti) spexin: identification, tissue distribution and mRNA expression responses to periprandial and fasting

(2015) Hongwei Wu et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism

(2015) Hyeong-Kyu Park et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Spexin peptide is expressed in human endocrine and epithelial tissues and reduced after glucose load in type 2 diabetes

(2015) Liping Gu et al.   PEPTIDES

Spexin Enhances Bowel Movement through Activating L-type Voltage-dependent Calcium Channel via Galanin Receptor 2 in Mice

(2015) Cheng-yuan Lin et al.   Scientific Reports

Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons

(2015) Amanda Laque et al.   Molecular Metabolism

Coevolution of the Spexin/Galanin/Kisspeptin Family: Spexin Activates Galanin Receptor Type II and III

(2014) Dong-Kyu Kim et al.   ENDOCRINOLOGY

Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity

(2014) José L. Walewski et al.   Obesity

Goldfish spexin: solution structure and novel function as a satiety factor in feeding control

(2013) Matthew K. H. Wong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A novel neuropeptide in suppressing luteinizing hormone release in goldfish, Carassius auratus

(2013) Yun Liu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Galanin and its receptors: A novel strategy for appetite control and obesity therapy

(2012) Penghua Fang et al.   PEPTIDES

Peptides derived from the prohormone proNPQ/spexin are potent central modulators of cardiovascular and renal function and nociception

(2011) Lawrence Toll et al.   FASEB JOURNAL

Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior

(2011) Peng-Hua Fang et al.   Neuroscience Bulletin

Spexin Expression in Normal Rat Tissues

(2010) Andrea Porzionato et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Central and Peripheral Administration of Secretin Inhibits Food Intake in Mice through the Activation of the Melanocortin System

(2010) Carrie Yuen Yee Cheng et al.   NEUROPSYCHOPHARMACOLOGY

Expression of the spexin gene in the rat adrenal gland and evidences suggesting that spexin inhibits adrenocortical cell proliferation

(2010) Marcin Rucinski et al.   PEPTIDES

C12ORF39, a novel secreted protein with a typical amidation processing signal

(2009) Bingbing Wan et al.   BIOSCIENCE REPORTS

Evolutionary Sequence Modeling for Discovery of Peptide Hormones

(2009) Kemal Sonmez et al.   PLoS Computational Biology