Susceptibility to 6-MP toxicity conferred by aNUDT15variant in Japanese children with acute lymphoblastic leukaemia

InheritedNUDT15Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia

(2015) Jun J. Yang et al.   JOURNAL OF CLINICAL ONCOLOGY

A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia

(2014) Suk-Kyun Yang et al.   NATURE GENETICS

Pharmacogenomics of acute lymphoid leukemia: new insights into treatment toxicity and efficacy

(2013) M. V. Relling et al.   Hematology-American Society of Hematology Education Program

Human MTH3 (NUDT18) Protein Hydrolyzes Oxidized Forms of Guanosine and Deoxyguanosine Diphosphates

(2012) Yasumitsu Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children

(2011) Yoichi Tanaka et al.   LEUKEMIA RESEARCH

Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Munster protocols

(2009) M. Stanulla et al.   BLOOD

Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study

(2009) K. Schmiegelow et al.   BLOOD

Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group Study L99-15

(2008) A. Manabe et al.   HAEMATOLOGICA