Macrophage beta2-adrenergic receptor is dispensable for the adipose tissue inflammation and function

Norepinephrine promotes triglyceride storage in macrophages via beta2‐adrenergic receptor activation

(2021) Kasparas Petkevicius et al.   FASEB JOURNAL

Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

(2020) Fanny Matheis et al.   CELL

HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation

(2020) Xanthe A.M.H. van Dierendonck et al.   Cell Reports

Treatment with a β-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity

(2020) Anastasia Kalinovich et al.   DIABETOLOGIA

Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis

(2020) Felipe Henriques et al.   Cell Reports

The involvement of neuroimmune cells in adipose innervation

(2020) Magdalena Blaszkiewicz et al.   MOLECULAR MEDICINE

Immunity and Inflammation in Atherosclerosis

(2019) Dennis Wolf et al.   CIRCULATION RESEARCH

Loss of intestinal sympathetic innervation elicits an innate immune driven colitis

(2019) Rose A. Willemze et al.   MOLECULAR MEDICINE

Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus

(2019) Adilson Guilherme et al.   Nature Reviews Endocrinology

Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C‐C Motif) Receptor 2‐Positive Macrophages and Lipolysis

(2019) Seung‐Jin Kim et al.   HEPATOLOGY

Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity

(2019) Maria S. Ioannou et al.   CELL

Augmented β2-adrenergic signaling dampens the neuroinflammatory response following ischemic stroke and increases stroke size

(2019) Kendra J. Lechtenberg et al.   Journal of Neuroinflammation

Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation

(2019) Cameron R. MacDonald et al.   RADIATION RESEARCH

Adipose Tissue-Resident Immune Cells in Obesity and Type 2 Diabetes

(2019) Jingli Lu et al.   Frontiers in Immunology

Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

(2019) Kasparas Petkevicius et al.   eLife

Obesity: a neuroimmunometabolic perspective

(2019) Chelsea M. Larabee et al.   Nature Reviews Endocrinology

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

(2019) Prashant Rajbhandari et al.   eLife

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure

(2018) Prashant Rajbhandari et al.   CELL

Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density

(2018) Jingyi Chi et al.   Cell Metabolism

Deletion of IRF8 (Interferon Regulatory Factor 8)-Dependent Dendritic Cells Abrogates Proatherogenic Adaptive ImmunityNovelty and Significance

(2018) Marc Clément et al.   CIRCULATION RESEARCH

Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation

(2018) Petra Kotzbeck et al.   JOURNAL OF LIPID RESEARCH

The β2-adrenergic receptor controls inflammation by driving rapid IL-10 secretion

(2018) Didem Ağaç et al.   BRAIN BEHAVIOR AND IMMUNITY

Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility

(2018) Sam Virtue et al.   Cell Reports

Uncoupling protein-1 deficiency promotes brown adipose tissue inflammation and ER stress

(2018) Laura M. Bond et al.   PLoS One

Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications

(2017) Hyunjin Noh et al.   KIDNEY INTERNATIONAL

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

(2017) Lawrence Kazak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type-2 innate lymphoid cells control the development of atherosclerosis in mice

(2017) Stephen A. Newland et al.   Nature Communications

Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages

(2016) Ilana Gabanyi et al.   CELL

The Adipose Tissue Microenvironment Regulates Depot-Specific Adipogenesis in Obesity

(2016) Elise Jeffery et al.   Cell Metabolism

Thermoneutral Housing Accelerates Metabolic Inflammation to Potentiate Atherosclerosis but Not Insulin Resistance

(2016) Xiao Yu Tian et al.   Cell Metabolism

Leukocyte-Expressed β2-Adrenergic Receptors Are Essential for Survival After Acute Myocardial InjuryClinical Perspective

(2016) Laurel A. Grisanti et al.   CIRCULATION

β2-Adrenergic receptor-dependent chemokine receptor 2 expression regulates leukocyte recruitment to the heart following acute injury

(2016) Laurel A. Grisanti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of ambient temperature promotes inflammation and initiates atherosclerosis in wild type C57BL/6 mice

(2016) Daniel A. Giles et al.   Molecular Metabolism

Fatty acids from fat cell lipolysis do not activate an inflammatory response but are stored as triacylglycerols in adipose tissue macrophages

(2015) Sylvie Caspar-Bauguil et al.   DIABETOLOGIA

Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages

(2015) Lijun Tang et al.   ENDOCRINOLOGY

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice

(2015) Gabriele Schoiswohl et al.   ENDOCRINOLOGY

Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans

(2015) S Virtue et al.   INTERNATIONAL JOURNAL OF OBESITY

Housing Temperature–Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling

(2015) Nicholas D. Leigh et al.   JOURNAL OF IMMUNOLOGY

Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation

(2015) Jason W.-L. Eng et al.   Nature Communications

Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility

(2014) Paul Andrew Muller et al.   CELL

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4

(2014) Bing Luan et al.   Cell Metabolism

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

(2014) Cecile Vernochet et al.   FASEB JOURNAL

β2-Adrenergic agonists augment air pollution–induced IL-6 release and thrombosis

(2014) Sergio E. Chiarella et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of M2 Regulatory Macrophages through the �2-Adrenergic Receptor with Protection during Endotoxemia and Acute Lung Injury

(2014) Jamison J. Grailer et al.   Journal of Innate Immunity

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

Crif1 Deficiency Reduces Adipose OXPHOS Capacity and Triggers Inflammation and Insulin Resistance in Mice

(2013) Min Jeong Ryu et al.   PLoS Genetics

BAFF Receptor Deficiency Reduces the Development of Atherosclerosis in Mice—Brief Report

(2012) Andrew P. Sage et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Hematopoietic Cell-Restricted Deletion of CD36 Reduces High-Fat Diet-Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue

(2011) H. T. Nicholls et al.   DIABETES

Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome — An allostatic perspective

(2010) Sam Virtue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?

(2010) S. E. McQuaid et al.   DIABETES

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION

The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

(2008) Eiichi Hinoi et al.   JOURNAL OF CELL BIOLOGY