Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

(2018) Christoph Schneider et al.   CELL

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

(2018) Marija S. Nadjsombati et al.   IMMUNITY

Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators

(2018) Carolyn A. Thomson et al.   JOURNAL OF IMMUNOLOGY

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

(2018) Weiwei Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tropism for tuft cells determines immune promotion of norovirus pathogenesis

(2018) Craig B. Wilen et al.   SCIENCE

A single-cell survey of the small intestinal epithelium

(2017) Adam L. Haber et al.   NATURE

Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

(2017) Mette Trauelsen et al.   Molecular Metabolism

Truncating Mutations in the Adhesion G Protein-Coupled Receptor G2 Gene ADGRG2 Cause an X-Linked Congenital Bilateral Absence of Vas Deferens

(2016) Olivier Patat et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Orphan Adhesion GPCR GPR64/ADGRG2 Is Overexpressed in Parathyroid Tumors and Attenuates Calcium-Sensing Receptor-Mediated Signaling

(2016) Nariman Balenga et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

(2016) M. R. Howitt et al.   SCIENCE

Tuft Cells: A New Flavor in Innate Epithelial Immunity

(2016) Richard K. Grencis et al.   TRENDS IN PARASITOLOGY

Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance

(2016) Robert Saddawi-Konefka et al.   Cell Reports

Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2

(2015) Lilian M. Demberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

(2015) Miriam C. Peeters et al.   CELLULAR SIGNALLING

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium

(2014) Tatsuya Yamaguchi et al.   BMC NEUROSCIENCE

Gut Microbiota-Produced Succinate Promotes C. difficile Infection after Antibiotic Treatment or Motility Disturbance

(2014) Jessica A. Ferreyra et al.   Cell Host & Microbe

Receptors for short-chain fatty acids in brush cells at the “gastric groove”

(2014) Julia Anna-Maria Eberle et al.   Frontiers in Physiology

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

(2013) Mark K. Nøhr et al.   ENDOCRINOLOGY

G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1

(2013) Günther HS Richter et al.   JOURNAL OF PATHOLOGY

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

(2013) Maja S. Engelstoft et al.   Molecular Metabolism

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

(2012) Yasunari Asano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The intestinal epithelium tuft cells: specification and function

(2012) François Gerbe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Cutting Edge: Regulation of Intestinal Inflammation and Barrier Function by IL-17C

(2012) Joseph M. Reynolds et al.   JOURNAL OF IMMUNOLOGY

GPR56 and the Developing Cerebral Cortex: Cells, Matrix, and Neuronal Migration

(2012) Kathleen Singer et al.   MOLECULAR NEUROBIOLOGY

Dclk1 distinguishes between tumor and normal stem cells in the intestine

(2012) Yuki Nakanishi et al.   NATURE GENETICS

Origin of the brush cell lineage in the mouse intestinal epithelium

(2011) Matthew Bjerknes et al.   DEVELOPMENTAL BIOLOGY

Gastric tuft cells express DCLK1 and are expanded in hyperplasia

(2011) Milena Saqui-Salces et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium

(2011) François Gerbe et al.   JOURNAL OF CELL BIOLOGY

Cholinergic microvillous cells in the mouse main olfactory epithelium and effect of acetylcholine on olfactory sensory neurons and supporting cells

(2011) Tatsuya Ogura et al.   JOURNAL OF NEUROPHYSIOLOGY

IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens

(2011) Xinyang Song et al.   NATURE IMMUNOLOGY

Cholinergic chemosensory cells in the trachea regulate breathing

(2011) G. Krasteva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPM5-expressing microvillous cells in the main olfactory epithelium

(2009) Weihong Lin et al.   BMC NEUROSCIENCE

DCAMKL-1 Expression Identifies Tuft Cells Rather Than Stem Cells in the Adult Mouse Intestinal Epithelium

(2009) François Gerbe et al.   GASTROENTEROLOGY

GPR56-Regulated Granule Cell Adhesion Is Essential for Rostral Cerebellar Development

(2009) S. Koirala et al.   JOURNAL OF NEUROSCIENCE

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

A Gut Feeling for Obesity: 7TM Sensors on Enteroendocrine Cells

(2008) Maja S. Engelstoft et al.   Cell Metabolism

Murine intestinal cells expressing Trpm5 are mostly brush cells and express markers of neuronal and inflammatory cells

(2008) C. Bezençon et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity

(2008) Tina Rubic et al.   NATURE IMMUNOLOGY