Dietary Betaine Mitigates Hepatic Steatosis and Inflammation Induced by a High-Fat-Diet by Modulating the Sirt1/Srebp-1/Pparɑ Pathway in Juvenile Black Seabream (Acanthopagrus schlegelii)

Pterostilbene Improves Hepatic Lipid Accumulation via the MiR-34a/Sirt1/SREBP-1 Pathway in Fructose-Fed Rats

(2020) Wen-Yuan Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Stress hormones modulate lipopolysaccharide stimulation of head kidney interleukin-6 production in the catfish Heteropneustes fossilis: In vivo and in vitro studies

(2019) Ravi Kumar et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Effects of supplemental dietary l-carnitine and bile acids on growth performance, antioxidant and immune ability, histopathological changes and inflammatory response in juvenile black seabream (Acanthopagrus schlegelii) fed high-fat diet

(2019) Min Jin et al.   AQUACULTURE

Betaine modulates oxidative stress, inflammation, apoptosis, autophagy, and Akt/mTOR signaling in methionine-choline deficiency-induced fatty liver disease

(2019) Milena Veskovic et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of NF-κB and the oxidative stress -dependent caspase-3 apoptotic pathway by betaine supplementation attenuates hepatic injury mediated by cisplatin in rats

(2019) Hanan Hagar et al.   Pharmacological Reports

Chronic inflammation is a key to inducing liver injury in blunt snout bream (Megalobrama amblycephala) fed with high-fat diet

(2019) Yong-Jun Dai et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Betaine supplementations enhance the intestinal immunity of on-growing grass carp (Ctenopharyngodon idella): Partly related to TOR and NF-κB signaling pathways

(2019) Hao Sun et al.   AQUACULTURE

Effects of dietary betaine in allogynogenetic gibel carp (Carassius auratus gibelio ): Enhanced growth, reduced lipid deposition and depressed lipogenic gene expression

(2018) Xiaojing Dong et al.   AQUACULTURE RESEARCH

Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury

(2018) Reza Heidari et al.   BIOMEDICINE & PHARMACOTHERAPY

Effects of berberine on growth, liver histology, and expression of lipid-related genes in blunt snout bream (Megalobrama amblycephala) fed high-fat diets

(2018) Wenhao Zhou et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats

(2018) Nannan Zhao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Visfatin regulates the production of lipopolysaccharide-induced inflammatory cytokines through p38 signaling in murine macrophages

(2018) Xin-Tong Wu et al.   MICROBIAL PATHOGENESIS

Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet

(2018) Jingjing Du et al.   Nutrients

High-fat-diet-induced inflammation depresses the appetite of blunt snout bream (Megalobrama amblycephala) through the transcriptional regulation of leptin/mammalian target of rapamycin

(2018) Yong-Jun Dai et al.   BRITISH JOURNAL OF NUTRITION

High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway

(2018) Xiu-Fei Cao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Omega-3 polyunsaturated fatty acids alleviate hepatic steatosis-induced inflammation through Sirt1-mediated nuclear translocation of NF-κB p65 subunit in hepatocytes of large yellow croaker ( Larmichthys crocea )

(2017) Tianjiao Wang et al.   FISH & SHELLFISH IMMUNOLOGY

Effect of dietary betaine on growth performance, antioxidant capacity and lipid metabolism in blunt snout bream fed a high-fat diet

(2017) Jean-Jacques Yao Adjoumani et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Betaine chemistry, roles, and potential use in liver disease

(2016) Christopher R. Day et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Betaine treatment decreased oxidative stress, inflammation, and stellate cell activation in rats with alcoholic liver fibrosis

(2016) İlknur Bingül et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Betaine prevented fructose-induced NAFLD by regulating LXRα/PPARα pathway and alleviating ER stress in rats

(2016) Chen-Xu Ge et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular Mechanism of Betaine on Hepatic Lipid Metabolism: Inhibition of Forkhead Box O1 (FoxO1) Binding to Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)

(2016) Dae Hyun Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Betaine supplementation prevents fatty liver induced by a high-fat diet: effects on one-carbon metabolism

(2015) Rafael Deminice et al.   AMINO ACIDS

Effects of dietary choline supplementation on growth performance, lipid deposition and intestinal enzyme activities of blunt snout breamMegalobrama amblycephalfed high-lipid diet

(2015) J.-Y. Li et al.   AQUACULTURE NUTRITION

Betaine supplementation mitigates cisplatin-induced nephrotoxicity by abrogation of oxidative/nitrosative stress and suppression of inflammation and apoptosis in rats

(2015) Hanan Hagar et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Activation of PPAR alpha by fenofibrate inhibits apoptosis in vascular adventitial fibroblasts partly through SIRT1-mediated deacetylation of FoxO1

(2015) Wei-rong Wang et al.   EXPERIMENTAL CELL RESEARCH

Dual-parallel inhibition of IL-10 and TGF-β1 controls LPS-induced inflammatory response via NF-κB signaling in grass carp monocytes/macrophages

(2015) He Wei et al.   FISH & SHELLFISH IMMUNOLOGY

Betaine is a feed enhancer for juvenile grouper (Epinephelus fuscoguttatus) as determined behaviourally

(2015) Leong-Seng Lim et al.   JOURNAL OF APPLIED ANIMAL RESEARCH

Physiological and molecular changes in large yellow croaker (Pseudosciaena croceaR.) with high-fat diet-induced fatty liver disease

(2013) Xinxia Wang et al.   AQUACULTURE RESEARCH

Docosahexaenoic acid improves vascular function via up-regulation of SIRT1 expression in endothelial cells

(2013) Saet-Byel Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Betaine supplementation protects against high-fructose-induced renal injury in rats

(2013) Chen-Yu Fan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes

(2013) Hui Chen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hepatic Methionine Homeostasis Is Conserved in C57BL/6N Mice on High-Fat Diet Despite Major Changes in Hepatic One-Carbon Metabolism

(2013) Christoph Dahlhoff et al.   PLoS One

The Metabolic Burden of Methyl Donor Deficiency with Focus on the Betaine Homocysteine Methyltransferase Pathway

(2013) Rima Obeid   Nutrients

When a turbot catches a fly: Evaluation of a pre-pupae meal of the Black Soldier Fly (Hermetia illucens) as fish meal substitute — Growth performance and chitin degradation in juvenile turbot (Psetta maxima)

(2012) S. Kroeckel et al.   AQUACULTURE

Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence

(2012) Hongwei Yao et al.   BIOCHEMICAL PHARMACOLOGY

Functional characterization of TNF-α in grass carp head kidney leukocytes: Induction and involvement in the regulation of NF-κB signaling

(2012) Anying Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

Effect of dietary betaine levels on growth performance and hepatic intermediary metabolism of GIFT strain of Nile tilapia Oreochromis niloticus reared in freshwater

(2010) Z. LUO et al.   AQUACULTURE NUTRITION

Dietary l-methionine requirement of juvenile black sea bream (Sparus macrocephalus) at a constant dietary cystine level

(2010) F. ZHOU et al.   AQUACULTURE NUTRITION

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

SIRT1 longevity factor suppresses NF-κB -driven immune responses: regulation of aging via NF-κB acetylation?

(2008) Antero Salminen et al.   BIOESSAYS

Impaired Sulfur-Amino Acid Metabolism and Oxidative Stress in Nonalcoholic Fatty Liver Are Alleviated by Betaine Supplementation in Rats

(2008) Do Y. Kwon et al.   JOURNAL OF NUTRITION