Aclidinium bromide/formoterol fumarate as a treatment for COPD: an update

Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline

(2020) Linda Nici et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pharmacotherapy For COPD: Molecules and Delivery Are Equally Important

(2020) Donald A Mahler et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Deterioration of Nighttime Respiratory Mechanics in Chronic Obstructive Pulmonary Disease: Impact of Bronchodilator Therapy

(2020) Nicolle J. Domnik et al.   CHEST

Effectiveness and Tolerability of LABA/LAMA Fixed-Dose Combinations Aclidinium/Formoterol, Glycopyrronium/Indacaterol and Umeclidinium/Vilanterol in the Treatment of COPD in Daily Practice – Results of the Non-Interventional DETECT Study

(2020) Tanja Plate et al.   International Journal of Chronic Obstructive Pulmonary Disease

Quality of Life and Limitations in Daily Life of Stable COPD Outpatients in a Real-World Setting in Austria – Results from the CLARA Project

(2020) Andreas Horner et al.   International Journal of Chronic Obstructive Pulmonary Disease

AMPLIFY: a randomized, Phase III study evaluating the efficacy and safety of aclidinium/formoterol vs monocomponents and tiotropium in patients with moderate-to-very severe symptomatic COPD

(2019) Sanjay Sethi et al.   International Journal of Chronic Obstructive Pulmonary Disease

Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT

(2019) Anthony D D'Urzo et al.   International Journal of Chronic Obstructive Pulmonary Disease

Effect of Aclidinium Bromide on Major Cardiovascular Events and Exacerbations in High-Risk Patients With Chronic Obstructive Pulmonary Disease

(2019) Robert A. Wise et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

One bronchodilator or two? Translating clinical trials into clinical practice

(2019) Dave Singh   RESPIROLOGY

ACLIDINIUM BROMIDE TREATMENT STRATIFIED BY EXACERBATION HISTORY: EFFECTS ON EXACERBATIONS AND MAJOR CARDIOVASCULAR EVENTS IN PATIENTS WITH COPD AND HIGH CARDIOVASCULAR RISK (ASCENT-COPD)

(2019) Robert Wise et al.   CHEST

An Evaluation Of Single And Dual Long-Acting Bronchodilator Therapy As Effective Interventions In Maintenance Therapy-Naïve Patients With COPD

(2019) Dave Singh et al.   International Journal of Chronic Obstructive Pulmonary Disease

Pharmacological mechanisms leading to synergy in fixed-dose dual bronchodilator therapy

(2018) Luigino Calzetta et al.   CURRENT OPINION IN PHARMACOLOGY

Drug Development for Asthma and COPD: A Regulatory Perspective

(2018) Marianne Mann et al.   Respiratory Care

Association of Cardiovascular Risk With Inhaled Long-Acting Bronchodilators in Patients With Chronic Obstructive Pulmonary Disease

(2018) Meng-Ting Wang et al.   JAMA Internal Medicine

Evaluation of the psychometric properties of the Early Morning Symptoms of COPD Instrument (EMSCI)

(2018) Asha Hareendran et al.   International Journal of Chronic Obstructive Pulmonary Disease

Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials

(2018) Mona Bafadhel et al.   Lancet Respiratory Medicine

Reply to: Different Background, Short Duration, Inappropriate Participants May Harm Your Conclusion.

(2018) Kenneth R Chapman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

LABA/LAMA fixed-dose combinations in patients with COPD: a systematic review

(2018) Paola Rogliani et al.   International Journal of Chronic Obstructive Pulmonary Disease

Tiotropium in Early-Stage Chronic Obstructive Pulmonary Disease

(2017) Yumin Zhou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Perception of symptoms and quality of life – comparison of patients’ and physicians’ views in the COPD MIRROR study

(2017) Bartolome Celli et al.   International Journal of Chronic Obstructive Pulmonary Disease

Beta-blocker under-use in COPD patients

(2017) Kuan Pin Lim et al.   International Journal of Chronic Obstructive Pulmonary Disease

ACTIVATE: the effect of aclidinium/formoterol on hyperinflation, exercise capacity, and physical activity in patients with COPD

(2017) Henrik Watz et al.   International Journal of Chronic Obstructive Pulmonary Disease

LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD: a systematic review and meta-analysis

(2017) Gustavo J Rodrigo et al.   International Journal of Chronic Obstructive Pulmonary Disease

Determinants of initial inhaled corticosteroid use in patients with GOLD A/B COPD: a retrospective study of UK general practice

(2017) James D. Chalmers et al.   npj Primary Care Respiratory Medicine

Beta-blockers in COPD: time for reappraisal

(2016) Brian Lipworth et al.   EUROPEAN RESPIRATORY JOURNAL

Efficacy and safety of aclidinium/formoterolversussalmeterol/fluticasone: a phase 3 COPD study

(2016) Claus Vogelmeier et al.   EUROPEAN RESPIRATORY JOURNAL

Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD

(2016) Jadwiga A. Wedzicha et al.   NEW ENGLAND JOURNAL OF MEDICINE

The efficacy of aclidinium/formoterol on lung function and symptoms in patients with COPD categorized by symptom status: a pooled analysis

(2016) Marc Miravitlles et al.   International Journal of Chronic Obstructive Pulmonary Disease

Prevention of clinically important deteriorations in COPD with umeclidinium/vilanterol

(2016) Dave Singh et al.   International Journal of Chronic Obstructive Pulmonary Disease

Blood Eosinophils: A Biomarker of Response to Extrafine Beclomethasone/Formoterol in Chronic Obstructive Pulmonary Disease

(2015) Salman H. Siddiqui et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanisms, assessment and therapeutic implications of lung hyperinflation in COPD

(2015) Andrea Rossi et al.   RESPIRATORY MEDICINE

Improvements in lung function with umeclidinium/vilanterol versus fluticasone propionate/salmeterol in patients with moderate-to-severe COPD and infrequent exacerbations

(2015) James F. Donohue et al.   RESPIRATORY MEDICINE

Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials

(2015) Steven Pascoe et al.   Lancet Respiratory Medicine

Minimal Clinically Important Differences in Pharmacological Trials

(2014) Paul W. Jones et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An official European Respiratory Society statement on physical activity in COPD

(2014) Henrik Watz et al.   EUROPEAN RESPIRATORY JOURNAL

Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene

(2014) Jin Hwa Lee et al.   RESPIRATORY MEDICINE

Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study

(2014) Dave Singh et al.   BMC Pulmonary Medicine

Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns

(2014) David Price et al.   International Journal of Chronic Obstructive Pulmonary Disease

Overtreatment of COPD with Inhaled Corticosteroids - Implications for Safety and Costs: Cross-Sectional Observational Study

(2013) Patrick White et al.   PLoS One

No room to breathe: the importance of lung hyperinflation in COPD

(2013) Mike Thomas et al.   Primary Care Respiratory Journal

Impact of night-time symptoms in COPD: a real-world study in five European countries

(2013) David Price et al.   International Journal of Chronic Obstructive Pulmonary Disease

The Genuair® inhaler: a novel, multidose dry powder inhaler

(2012) H. Chrystyn et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials

(2012) Yaa-Hui Dong et al.   THORAX

What the pulmonary specialist should know about the new inhalation therapies

(2011) B. L. Laube et al.   EUROPEAN RESPIRATORY JOURNAL

AGREE II: advancing guideline development, reporting and evaluation in health care

(2010) M. C. Brouwers et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Impact of changes in physical activity on health-related quality of life among patients with COPD

(2010) C. Esteban et al.   EUROPEAN RESPIRATORY JOURNAL

Symptom variability in patients with severe COPD: a pan-European cross-sectional study

(2010) R. Kessler et al.   EUROPEAN RESPIRATORY JOURNAL

Mortality in the 4-Year Trial of Tiotropium (UPLIFT) in Patients with Chronic Obstructive Pulmonary Disease

(2009) Bartolome Celli et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Peak inspiratory flow through the Genuair® inhaler in patients with moderate or severe COPD

(2009) H. Magnussen et al.   RESPIRATORY MEDICINE

Inhaled Anticholinergics and Risk of Major Adverse Cardiovascular Events in Patients With Chronic Obstructive Pulmonary Disease

(2008) Sonal Singh   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A 4-Year Trial of Tiotropium in Chronic Obstructive Pulmonary Disease

(2008) Donald P. Tashkin et al.   NEW ENGLAND JOURNAL OF MEDICINE