Ibuprofen and COVID-19 disease: separating the myths from facts

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

(2020) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry

(2020) Milena Gianfrancesco et al.   ANNALS OF THE RHEUMATIC DISEASES

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution

(2020) Walter Gottlieb Land   Molecular Diagnosis & Therapy

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

(2020) Lei Fang et al.   Lancet Respiratory Medicine

COVID-19 Infection and Circulating ACE2 Levels: Protective Role in Women and Children

(2020) Elena Ciaglia et al.   Frontiers in Pediatrics

Risk factors for hospital admissions related to COVID-19 in patients with autoimmune inflammatory rheumatic diseases

(2020) Dalifer D Freites Nuñez et al.   ANNALS OF THE RHEUMATIC DISEASES

Ibuprofen use and clinical outcomes in COVID-19 patients

(2020) E. Rinott et al.   CLINICAL MICROBIOLOGY AND INFECTION

The COVID-19 Cytokine Storm; What We Know So Far

(2020) Dina Ragab et al.   Frontiers in Immunology

Prior Routine Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Important Outcomes in Hospitalised Patients with COVID-19

(2020) Eilidh Bruce et al.   Journal of Clinical Medicine

The complement system in COVID-19: friend and foe?

(2020) Anuja Java et al.   JCI Insight

Association Between Prescribed Ibuprofen and Severe COVID‐19 Infection: A Nationwide Register‐Based Cohort Study

(2020) Kristian Kragholm et al.   CTS-Clinical and Translational Science

Adverse outcomes and mortality in users of non-steroidal anti-inflammatory drugs who tested positive for SARS-CoV-2: A Danish nationwide cohort study

(2020) Lars Christian Lund et al.   PLOS MEDICINE

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia

(2020) Carlos Salama et al.   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic mechanisms of ibuprofen, prednisone and betamethasone in osteoarthritis

(2016) Fenglong Sun et al.   Molecular Medicine Reports

Ibuprofen Attenuates Cardiac Fibrosis in Streptozotocin-Induced Diabetic Rats

(2015) Weili Qiao et al.   CARDIOLOGY

PharmGKB summary

(2015) Liudmila L. Mazaleuskaya et al.   Pharmacogenetics and Genomics

The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial

(2013) L. Gallelli et al.   OSTEOARTHRITIS AND CARTILAGE

Ibuprofen Modulates NF-ĸB Activity but Not IL-8 Production in Cystic Fibrosis Respiratory Epithelial Cells

(2009) Nurlan Dauletbaev et al.   RESPIRATION

Cytokine profile in human skin in response to experimental inflammation, noxious stimulation, and administration of a COX-inhibitor: A microdialysis study

(2008) M. S. Angst et al.   PAIN

Ibuprofen administration attenuates serum TNF-α levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation

(2008) S CAZANAVE et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY