Osteoporosis Remission and New Bone Formation with Mesoporous Silica Nanoparticles

Overview of treatment approaches to osteoporosis

(2020) Bente L. Langdahl   BRITISH JOURNAL OF PHARMACOLOGY

Emerging therapeutic targets for osteoporosis

(2020) Luigi Gennari et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis

(2020) Miguel Gisbert-Garzarán et al.   Pharmaceutics

Mesoporous Silica Nanoparticles for Co-Delivery of Drugs and Nucleic Acids in Oncology: A Review

(2020) Juan L. Paris et al.   Pharmaceutics

Nanoparticles to Knockdown Osteoporosis-Related Gene and Promote Osteogenic Marker Expression for Osteoporosis Treatment

(2019) Patricia Mora-Raimundo et al.   ACS Nano

Strategies, design, and chemistry in siRNA delivery systems

(2019) Yizhou Dong et al.   ADVANCED DRUG DELIVERY REVIEWS

RNAi therapeutic and its innovative biotechnological evolution

(2019) Yuhua Weng et al.   BIOTECHNOLOGY ADVANCES

siRNA therapeutics: a clinical reality

(2019) Phei Er Saw et al.   Science China-Life Sciences

State of the art in osteoporosis risk assessment and treatment

(2019) J. Liu et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine

(2019) Omer Adir et al.   ADVANCED MATERIALS

Mesoporous Silica Nanoparticles for Drug Delivery

(2019) Miguel Manzano et al.   ADVANCED FUNCTIONAL MATERIALS

Osteostatin Inhibits Collagen-Induced Arthritis by Regulation of Immune Activation, Pro-Inflammatory Cytokines, and Osteoclastogenesis

(2019) Josep Nácher-Juan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanoparticles for multimodal antivascular therapeutics: Dual drug release, photothermal and photodynamic therapy

(2019) Juan L. Paris et al.   Acta Biomaterialia

Combination therapies in the treatment of osteoporosis

(2019) Jennifer J. Kelly et al.   Current Opinion in Endocrinology Diabetes and Obesity

Mesoporous silica nanoparticles in nanomedicine applications

(2018) Miguel Manzano et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

From proof-of-concept material to PEGylated and modularly targeted ultrasound-responsive mesoporous silica nanoparticles

(2018) Juan L. Paris et al.   Journal of Materials Chemistry B

Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains

(2018) S. Portal-Núñez et al.   Bone & Joint Research

Mixed-charge pseudo-zwitterionic mesoporous silica nanoparticles with low-fouling and reduced cell uptake properties

(2018) Noemí Encinas et al.   Acta Biomaterialia

Osteoporosis: a clinical and pharmacological update

(2018) Maritza Vidal et al.   CLINICAL RHEUMATOLOGY

Anabolic Therapies in Osteoporosis and Bone Regeneration

(2018) Gabriele Russow et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanoparticle Formulation of Moxifloxacin and Intramuscular Route of Delivery Improve Antibiotic Pharmacokinetics and Treatment of Pneumonic Tularemia in a Mouse Model

(2018) Daniel L. Clemens et al.   ACS Infectious Diseases

New Insights Into the Local and Systemic Functions of Sclerostin: Regulation of Quiescent Bone Lining Cells and Beige Adipogenesis in Peripheral Fat Depots

(2017) Jesus Delgado-Calle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Administration Converts Bone Lining Cells Into Active Osteoblasts

(2017) Sang Wan Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effects of Combination Therapy of Alendronate and Hormonal Therapy on Bone Mineral Density in Postmenopausal Korean Women: Multicenter, Randomized Controlled Clinical Trial

(2017) Byung-Koo Yoon et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights

(2017) María Vallet-Regí et al.   MOLECULES

A novel visible light responsive nanosystem for cancer treatment

(2017) M. Martínez-Carmona et al.   Nanoscale

Sclerostin: Intracellular mechanisms of action and its role in the pathogenesis of skeletal and vascular disorders

(2017) Barbara Pietrzyk et al.   Advances in Clinical and Experimental Medicine

The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth

(2016) Peipei Duan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dual-Responsive Mesoporous Silica Nanoparticles Mediated Codelivery of Doxorubicin and Bcl-2 SiRNA for Targeted Treatment of Breast Cancer

(2016) Xiaojun Zhou et al.   Journal of Physical Chemistry C

Emerging Frontiers in Drug Delivery

(2016) Mark W. Tibbitt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in mesoporous silica nanoparticles for antitumor therapy: our contribution

(2016) Alejandro Baeza et al.   Biomaterials Science

Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo

(2016) Genc Basha et al.   Molecular Therapy-Nucleic Acids

Local drug delivery for enhancing fracture healing in osteoporotic bone

(2015) Laura Kyllönen et al.   Acta Biomaterialia

Animal models for osteoporosis

(2015) Toshihisa Komori   EUROPEAN JOURNAL OF PHARMACOLOGY

Bone biology, signaling pathways, and therapeutic targets for osteoporosis

(2015) Nicole M. Iñiguez-Ariza et al.   MATURITAS

Wnt and the Wnt signaling pathway in bone development and disease

(2014) Yiping Wang   Frontiers in Bioscience-Landmark

Intrinsic Tryptophan Fluorescence in the Detection and Analysis of Proteins: A Focus on Förster Resonance Energy Transfer Techniques

(2014) Amar Ghisaidoobe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-viral nanocarriers for siRNA delivery in breast cancer

(2014) Jing Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Treatment with N- and C-Terminal Peptides of Parathyroid Hormone-Related Protein Partly Compensate the Skeletal Abnormalities in IGF-I Deficient Mice

(2014) Lourdes Rodríguez-de la Rosa et al.   PLoS One

Teriparatide and denosumab, alone or combined, in women with postmenopausal osteoporosis: the DATA study randomised trial

(2013) Joy N Tsai et al.   LANCET

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Enhanced siRNA Delivery and Silencing Gold–Chitosan Nanosystem with Surface Charge-Reversal Polymer Assembly and Good Biocompatibility

(2012) Lu Han et al.   ACS Nano

Bone targeting for the treatment of osteoporosis

(2011) Tessa Luhmann et al.   JOURNAL OF CONTROLLED RELEASE

Linear PEI nanoparticles: efficient pDNA/siRNA carriers in vitro and in vivo

(2011) Ritu Goyal et al.   Nanomedicine-Nanotechnology Biology and Medicine

Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line

(2010) Huan Meng et al.   ACS Nano

Sclerostin: Current Knowledge and Future Perspectives

(2010) M. J. C. Moester et al.   CALCIFIED TISSUE INTERNATIONAL

Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats

(2010) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effects of intravenous zoledronic acid plus subcutaneous teriparatide [rhPTH(1-34)] in postmenopausal osteoporosis

(2010) Felicia Cosman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Update in New Anabolic Therapies for Osteoporosis

(2010) Ernesto Canalis   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mesoporous Silica Nanoparticles Facilitate Delivery of siRNA to Shutdown Signaling Pathways in Mammalian Cells

(2010) Christopher Hom et al.   Small

Direct effects of osteoprotegerin on human bone cell metabolism

(2009) Alexander Grundt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF

(2009) Ernestina Schipani et al.   JOURNAL OF BONE AND MINERAL RESEARCH