Article
Biophysics
Hadi Mirzajani, Taher Abbasiasl, Fariborz Mirlou, Emin Istif, Mohammad Javad Bathaei, Cagdas Dag, Oguzhan Deyneli, Dilek Yazici, Levent Beker
Summary: Glucose monitoring before, during, and after exercise is crucial for individuals with diabetes due to the increased risk of hyper- and hypo-glycemic events. A compact wearable glucose monitoring device was proposed for sweat analysis, featuring a flexible and conformal structure with excellent operating characteristics.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Materials Science, Multidisciplinary
Brince Paul, Silvia Demuru, Celine Lafaye, Mathieu Saubade, Danick Briand
Summary: This study presents a printed iontophoretic-integrated fluidic sweat patch for on-demand real-time monitoring of sweat in stationary conditions. The system features a multisensing sensor array with high sensitivity to sodium, potassium, and pH, making it suitable for real-time monitoring of individual health status.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Chemistry, Multidisciplinary
Hao Zhao, Xieli Zhang, Yanxia Qin, Yong Xia, Xin Xu, Xiguang Sun, Dehai Yu, Samuel M. Mugo, Dong Wang, Qiang Zhang
Summary: An integrated wearable sweat-sensing patch is demonstrated for continuous analysis of stress biomarkers at rest. It utilizes a microfluidic chip for sweat collection without perspiration assistance and has a ternary composite electrode for high sensitivity to trace stress biomarkers. The on-site signal processing circuitry enables signal transduction, conditioning, processing, and wireless transmission, with the detection results displayed on a smartphone through software.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Review
Chemistry, Analytical
Emanuel Bilbao, Octavio Garate, Theo Rodriguez Campos, Mariano Roberti, Mijal Mass, Alex Lozano, Gloria Longinotti, Leandro Monsalve, Gabriel Ybarra
Summary: Sweat analysis using minimally invasive wearable sensors has the potential to disrupt the assessment of clinical parameters, with exciting applications in early medical diagnostics and high-performance sports. Electrochemical sensors and biosensors are particularly attractive for their ability to electronically integrate with wearable devices. In this article, we review the potential and limitations of electrochemical sweat (bio)sensors, including target analytes, transduction techniques, sweat sample collection, miniaturized electronic instrumentation, and machine learning signal processing.
Article
Multidisciplinary Sciences
Qing Hao, Xiao-Rui Ren, Yichen Chen, Chao Zhao, Jingyi Xu, Dong Wang, Hong Liu
Summary: Covalent organic frameworks are increasingly being used in the design of stimuli-responsive materials. In this study, a sweat-responsive covalent organic framework film was designed for material-based fingerprint liveness detection. The color change induced by sweat can intuitively distinguish living fingers from fake fingerprints. Additionally, the collection and analysis of sweat pore distribution can be achieved by simplifying the sample handling steps.
NATURE COMMUNICATIONS
(2023)
Review
Chemistry, Multidisciplinary
Zhengyun Wang, Jihoon Shin, Jin-Ho Park, Hakho Lee, Dong-Hwan Kim, Hongfang Liu
Summary: Sweat sensors have great potential for on-body health monitoring, but they are hindered by challenges such as high materials costs and complex technology.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Analytical
Pengyu Xi, Xuecheng He, Chuan Fan, Qinglin Zhu, Zehua Li, Yuemeng Yang, Xin Du, Tailin Xu
Summary: This paper proposes a one-way colorimetric sweat sampling and sensing system based on a Janus fabric using interfacial modification techniques. The Janus fabric's opposite wettability enables quick movement of sweat from the skin surface to the hydrophilic side and colorimetric patches. This system not only facilitates sweat sampling but also prevents backflow of colorimetric reagent, eliminating potential epidermal contaminations. Visual and portable detection of sweat biomarkers, including chloride, pH, and urea, is achieved, bridging the gap between sweat sampling and a friendly epidermal microenvironment.
Review
Chemistry, Multidisciplinary
Tamoghna Saha, Rafael Del Cano, Ernesto la De Paz, Samar S. Sandhu, Joseph Wang
Summary: Sweat is an important biofluid that regulates body temperature and contains biomarkers similar to those found in blood. This review provides a comprehensive report on approaches to collect and sense sweat from the skin, as well as discusses the advances and applications of sweat sensing technology.
Article
Chemistry, Analytical
Francesca Criscuolo, Ivan Ny Hanitra, Simone Aiassa, Irene Taurino, Nicolo Oliva, Sandro Carrara, Giovanni De Micheli
Summary: This study introduces a novel wearable multi-electrode platform that efficiently addresses some challenges in sweat sensing technology. By optimizing sensing technology and sample handling, this platform shows high accuracy and feasibility in various applications, such as sport tracking and heavy metal contamination monitoring.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Navya Mishra, Nate T. Garland, Krystyn A. Hewett, Mohammad Shamsi, Michael D. Dickey, Amay J. Bandodkar
Summary: Wearable sweat sensors have the advantages of easy sample collection, physiological relevance, and the ability to noninvasively monitor the human body. This study introduces new concepts in wearable microfluidic platforms that allow users to choose the time for sample analysis and select sensors for specific conditions. The technology involves finger-actuated pumps, valves, and sensors incorporated within soft, wearable microfluidics. A two-day-long human pilot study validates the system's on-demand, longitudinal, and multianalyte sensing capabilities.
Review
Engineering, Electrical & Electronic
Kan Kan Yeung, Ting Huang, Yunzhi Hua, Kai Zhang, Matthew M. F. Yuen, Zhaoli Gao
Summary: This review highlights the recent progress in the development and application of electrochemical sweat sensors and self-powered systems for wearable applications, including various types of sensors and novel functional nanomaterials. The advancement of battery-free wearable devices, such as self-powered biofuel cells and energy harvesting from novel materials, are also discussed, along with the challenges and opportunities in developing sweat sensor-based wearable systems for future directions.
IEEE SENSORS JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
Ashwin Aggarwal, Manik Dautta, Luis Fernando Ayala-Cardona, Aalaya Wudaru, Ali Javey
Summary: The rapid advancements in wearable technologies have enabled the development of personal monitoring systems for core bodily metrics. Current smartwatches accurately monitor physical signals like heart rate and respiratory rate, but they are unable to track several important physiological parameters, including sweat rate. This study presents a new wearable device that can track sweat rate using an off-the-shelf humidity sensor. The device features a 3D-printed chamber with a humidity sensor and microheater, and it interfaces with the skin using a malleable and concave sweat collector. Through experiments, the authors aim to understand the relationship between sweat-induced humidity and the amount of sweat secreted. Compared to existing sweat rate sensing devices, this hygrometer-based device is more comfortable for extended wear and can be used alongside microfluidic-based sweat rate devices.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Engineering, Biomedical
Wenzheng Heng, Geng Yang, Woo Soo Kim, Kaichen Xu
Summary: Sweat sensors offer a noninvasive way to monitor human health conditions by utilizing the information contained in sweat for personalized big data analysis. The development of wearable sweat sensors has enabled low-cost, real-time, in situ sweat measurements, opening up new opportunities for health status evaluation based on personalized data.
BIO-DESIGN AND MANUFACTURING
(2022)
Article
Biophysics
Gisela Ibanez-Redin, Giovana Rosso Cagnani, Nathalia O. Gomes, Paulo A. Raymundo-Pereira, Sergio A. S. Machado, Marco Antonio Gutierrez, Jose Eduardo Krieger, Osvaldo N. Oliveira
Summary: In this study, we developed wearable potentiometric biosensors for monitoring urea in sweat. The biosensors were designed to detect urea at different pH values and included a pH sensor, polyaniline ink, urease bioink, and a polyvinylchloride membrane. The biosensors exhibited fast response time, no interference from other substances in sweat, and reliable urea detection in undiluted human sweat using a skin-worn flexible device with pH correction strategy. The performance of the biosensors was not affected by severe bending strains, and mass production was also demonstrated using slot-die coating with a roll-to-roll technique.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Badrinath Jagannath, Madhavi Pali, Kai-Chun Lin, Devangsingh Sankhala, Pejman Naraghi, Sriram Muthukumar, Shalini Prasad
Summary: This work demonstrates the discovery, quantification, and validation of infection prognostic markers, IP-10 and TRAIL, in human sweat using wearable technology. It also shows the potential of a wearable SWEATSENSER device for continuous monitoring of infection markers.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Nanoscience & Nanotechnology
Noemie-Manuelle Dorval Courchesne, Elizabeth P. DeBenedictis, Jason Tresback, Jessica J. Kim, Anna Duraj-Thatte, David Zanuy, Sinan Keten, Neel S. Joshi
Article
Engineering, Chemical
Sophia Roy, Oliver Xie, Noemie-Manuelle Dorval Courchesne
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2020)
Article
Multidisciplinary Sciences
Dalia Jane Saldanha, Zahra Abdali, Daniel Modafferi, Bita Janfeshan, Noemie-Manuelle Dorval Courchesne
SCIENTIFIC REPORTS
(2020)
Article
Biochemical Research Methods
Zahra Abdali, Masoud Aminzare, Xiaodan Zhu, Elizabeth DeBenedictis, Oliver Xie, Sinan Keten, Noemie-Manuelle Dorval Courchesne
ACS SYNTHETIC BIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Anna M. Duraj-Thatte, Avinash Manjula-Basavanna, Noemie-Manuelle Dorval Courchesne, Giorgia I. Cannici, Antoni Sanchez-Ferrer, Benjamin P. Frank, Leonie Van't Hag, Sarah K. Cotts, D. Howard Fairbrother, Raffaele Mezzenga, Neel S. Joshi
Summary: Petrochemical-based plastics are causing irreversible damage to the ecosystem, highlighting the urgent need for more biodegradable alternatives. Aquaplastic, a new microbial biofilm-based biodegradable bioplastic, offers unique characteristics such as water processability and strong resistance to various solvents, making it a promising material for packaging and coating applications.
NATURE CHEMICAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Zahra Abdali, Max Renner-Rao, Amy Chow, Anqi Cai, Matthew J. Harrington, Noemie-Manuelle Dorval Courchesne
Summary: This study reports the use of an adapted secretion pathway for extracellular secretion of bacterial collagen, simplifying the isolation process and enabling a simple cost-effective production method.
Review
Engineering, Chemical
Patricia Moraille, Zahra Abdali, Mohini Ramkaran, David Polcari, Gregory S. Patience, Noemie-Manuelle Dorval Courchesne, Antonella Badia
Summary: Atomic force microscopy (AFM) is a microscopy technique that allows high-resolution imaging of surface topography and characterization of material properties. AFM offers various imaging modes and can simultaneously measure the physical and chemical properties of materials. Recent advances combine AFM with infrared spectroscopy to enable simultaneous mapping of surface topography and chemical species distribution.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Materials Science, Biomaterials
Catrina Huyer, Daniel Modafferi, Masoud Aminzare, Juliana Ferraro, Zahra Abdali, Sophia Roy, Dalia Jane Saldanha, Saadia Wasim, Johan Alberti, Shurui Feng, Fabio Cicoira, Noemie-Manuelle Dorval Courchesne
Summary: Mixing curli fibers with PEDOT:PSS can significantly enhance the conductivity and self-healing ability of the composite. Additionally, the addition of curli fibers can improve the flexibility and biocompatibility of the composite. This method can broaden the applications of PEDOT:PSS in biointerfaces and bioelectronics.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Engineering, Biomedical
Zahra Abdali, Masoud Aminzare, Amy Chow, Noemie-Manuelle Dorval Courchesne
Summary: Bacterial collagen, with its special arrangement and charged residues, can be used to nucleate three different inorganic materials and form collagen/mineral composites with more uniform particle size distribution. The gelation of silica during mineralization allows for the production of processable self-standing collagen composites. Therefore, combining bacterial collagen with minerals extends their applications in biomaterials and tissue engineering, particularly for bone regenerative scaffolds.
BIOMEDICAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Masoud Aminzare, Ehsan Hamzehpoor, Sara Mahshid, Noemie-Manuelle Dorval Courchesne
Summary: This article presents a facile strategy for synthesizing stable methylammonium lead halide perovskite nanocrystals in an aqueous environment using diverse proteins as capping agents. The synthesized protein-HPNCs exhibit high stability and optical characteristics, making them suitable for various applications such as cell imaging and sensing.
ACS APPLIED NANO MATERIALS
(2022)
Review
Chemistry, Multidisciplinary
Masoud Aminzare, Jennifer Jiang, Gabrielle A. A. Mandl, Sara Mahshid, John A. A. Capobianco, Noemie-Manuelle Dorval Courchesne
Summary: Halide perovskite nanocrystals (HPNCs) have become a forefront research topic in nanomaterials. The use of biomolecules as ligands has shown promise in improving the properties and applications of HPNCs. This review summarizes recent advances in incorporating biomolecules into high-performance HPNCs for biological and environmental applications.
Article
Multidisciplinary Sciences
Anqi Cai, Zahra Abdali, Dalia Jane Saldanha, Masoud Aminzare, Noemie-Manuelle Dorval Courchesne
Summary: In order to address the environmental impact of the textile industry, self-repairing textile composites have been developed by integrating Escherichia coli biofilms into conventional textiles. The curli fibers in the biofilm have demonstrated the ability to self-assemble and self-heal. Through simple and scalable methods, such as adsorption, doctor blading, and vacuum filtration, the biofilms were successfully integrated into the textiles.
SCIENTIFIC REPORTS
(2023)