Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations
Authors
Keywords
-
Journal
Stem Cell Reports
Volume 16, Issue 6, Pages 1527-1541
Publisher
Elsevier BV
Online
2021-05-27
DOI
10.1016/j.stemcr.2021.04.021
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Generation of an ALS human iPSC line KEIOi001-A from peripheral blood of a Charcot disease-affected patient carrying TARDBP p.N345K heterozygous SNP mutation
- (2020) Nicolas Leventoux et al. Stem Cell Research
- Mutant TDP-43 Causes Early-Stage Dose-Dependent Motor Neuron Degeneration in a TARDBP Knockin Mouse Model of ALS
- (2019) Sarah Y. Ebstein et al. Cell Reports
- Modeling Motor Neuron Resilience in ALS Using Stem Cells
- (2019) Ilary Allodi et al. Stem Cell Reports
- Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons
- (2019) Disi An et al. eLife
- Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons
- (2019) Tetsuya Akiyama et al. EBioMedicine
- DESOGESTREL DOWN-REGULATES PHOX2B AND ITS TARGET GENES IN PROGESTERONE RESPONSIVE NEUROBLASTOMA CELLS
- (2018) Silvia Cardani et al. EXPERIMENTAL CELL RESEARCH
- Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent
- (2018) Koki Fujimori et al. NATURE MEDICINE
- Altered Expression of Phox2 Transcription Factors in the Locus Coeruleus in Major Depressive Disorder Mimicked by Chronic Stress and Corticosterone Treatment In Vivo and In Vitro
- (2018) Yan Fan et al. NEUROSCIENCE
- Genetic mutations in RNA-binding proteins and their roles in ALS
- (2017) Katannya Kapeli et al. HUMAN GENETICS
- Structural and functional differences in PHOX2B frameshift mutations underlie isolated or syndromic congenital central hypoventilation syndrome
- (2017) Simona Di Lascio et al. HUMAN MUTATION
- Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis
- (2017) Ayumi Nishiyama et al. NEUROBIOLOGY OF AGING
- Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells
- (2017) Koki Fujimori et al. Stem Cell Reports
- Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons
- (2017) Jiro Kawada et al. Stem Cell Reports
- Alanine Expansions Associated with Congenital Central Hypoventilation Syndrome Impair PHOX2B Homeodomain-mediated Dimerization and Nuclear Import
- (2016) Simona Di Lascio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
- (2016) Feng Tian et al. Nature Communications
- Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish
- (2015) Aurélie Stil et al. Developmental Neurobiology
- Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells
- (2015) Daisuke Shimojo et al. Molecular Brain
- Futsch/MAP1B mRNA Is a Translational Target of TDP-43 and Is Neuroprotective in a Drosophila Model of Amyotrophic Lateral Sclerosis
- (2014) A. N. Coyne et al. JOURNAL OF NEUROSCIENCE
- Zebrafish models of human motor neuron diseases: Advantages and limitations
- (2014) Patrick J. Babin et al. PROGRESS IN NEUROBIOLOGY
- Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity
- (2013) Esteban O Mazzoni et al. NATURE NEUROSCIENCE
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models
- (2013) Desheng Pei et al. PLoS Genetics
- Autonomic neurocristopathy-associated mutations in PHOX2B dysregulate Sox10 expression
- (2012) Mayumi Nagashimada et al. JOURNAL OF CLINICAL INVESTIGATION
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation
- (2010) Y. Nakano et al. DEVELOPMENT
- Zebrafish models of collagen VI-related myopathies
- (2010) W.R. Telfer et al. HUMAN MOLECULAR GENETICS
- Amyotrophic lateral sclerosis
- (2009) Lokesh C Wijesekera et al. Orphanet Journal of Rare Diseases
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search