Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-05-21
DOI
10.3389/fphar.2021.658513
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells
- (2021) Ge Li et al. PHARMACEUTICAL BIOLOGY
- Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors
- (2020) Ashraf N. Abdalla et al. MOLECULES
- Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells
- (2020) Mohamed E. Abdallah et al. MOLECULES
- The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes
- (2020) Safaa Yehia Eid et al. PHYTOMEDICINE
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application
- (2018) Ana Seca et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Resveratrol Mediated Cancer Cell Apoptosis, and Modulation of Multidrug Resistance Proteins and Metabolic Enzymes
- (2018) Mahmoud Zaki El-Readi et al. PHYTOMEDICINE
- Fallopia japonica, a Natural Modulator, Can Overcome Multidrug Resistance in Cancer Cells
- (2015) Safaa Yehia Eid et al. Evidence-based Complementary and Alternative Medicine
- From Cascaded Catalytic Nucleic Acids to Enzyme–DNA Nanostructures: Controlling Reactivity, Sensing, Logic Operations, and Assembly of Complex Structures
- (2014) Fuan Wang et al. CHEMICAL REVIEWS
- Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function
- (2014) Frances Jane Sharom Frontiers in Oncology
- Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells
- (2013) Safaa Yehia Eid et al. PHYTOMEDICINE
- P-Glycoprotein-ATPase Modulation: The Molecular Mechanisms
- (2012) Xiaochun Li-Blatter et al. BIOPHYSICAL JOURNAL
- The ABC of the Blood-Brain Barrier - Regulation of Drug Efflux Pumps
- (2012) Anne Mahringer et al. CURRENT PHARMACEUTICAL DESIGN
- Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway
- (2012) Ming-Rong Cao et al. Hepatobiliary & Pancreatic Diseases International
- Sanguinarine Induces Apoptosis of HT-29 Human Colon Cancer Cells via the Regulation of Bax/Bcl-2 Ratio and Caspase-9-Dependent Pathway
- (2012) Jun Sik Lee et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transporters
- (2012) Safaa Yehia Eid et al. PHYTOMEDICINE
- Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells
- (2012) Safaa Yehia Eid et al. PHYTOMEDICINE
- Modulation of multidrug resistance in cancer cells by chelidonine and Chelidonium majus alkaloids
- (2012) Mahmoud Zaki El-Readi et al. PHYTOMEDICINE
- Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents
- (2012) Michael Wink et al. Frontiers in Microbiology
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Targeting the extrinsic apoptosis signaling pathway for cancer therapy
- (2011) Thomas J. Sayers CANCER IMMUNOLOGY IMMUNOTHERAPY
- The P-glycoprotein multidrug transporter
- (2011) Frances J. Sharom Essays in Biochemistry
- The emerging role of P-glycoprotein inhibitors in drug delivery: a patent review
- (2011) Naseem Akhtar et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Intracellular trafficking of P-glycoprotein
- (2011) Dong Fu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs
- (2011) Tolga Eichhorn et al. JOURNAL OF ETHNOPHARMACOLOGY
- Embryonic toxicity of sanguinarine through apoptotic processes in mouse blastocysts
- (2011) Wen-Hsiung Chan TOXICOLOGY LETTERS
- The Interaction of Telomere DNA G-Quadruplex with Three bis-Benzyltetrahydroisoquinoline Alkaloids
- (2011) Xiaohui Ji et al. Nucleic Acid Therapeutics
- Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma
- (2011) Thayele Hamsa et al. Chinese Medicine
- Complex Interactions between Phytochemicals. The Multi-Target Therapeutic Concept of Phytotherapy
- (2010) Thomas Efferth et al. CURRENT DRUG TARGETS
- Synergy research: Approaching a new generation of phytopharmaceuticals
- (2010) Hildebert Wagner FITOTERAPIA
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
- (2010) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Mitochondria and cell death: outer membrane permeabilization and beyond
- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cancer Therapy with Natural Products and Medicinal Plants
- (2010) Thomas Efferth PLANTA MEDICA
- Advancement of Structure-Activity Relationship of Multidrug Resistance-Associated Protein 2 Interactions
- (2009) Li Xing et al. AAPS Journal
- ABC Efflux Pump-Based Resistance to Chemotherapy Drugs
- (2009) Paul D. W. Eckford et al. CHEMICAL REVIEWS
- Overcoming Drug Resistance by Enhancing Apoptosis of Tumor Cells
- (2009) Pepita Gimenez-Bonafe et al. CURRENT CANCER DRUG TARGETS
- Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?
- (2009) Bhushan Patwardhan et al. DRUG DISCOVERY TODAY
- Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines
- (2009) Mahmoud Zaki El-Readi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Drug development costs when financial risk is measured using the Fama-French three-factor model
- (2009) John A. Vernon et al. HEALTH ECONOMICS
- Potent and Selective Inhibitors of Breast Cancer Resistance Protein (ABCG2) Derived from thep-Glycoprotein (ABCB1) Modulator Tariquidar
- (2009) Matthias Kühnle et al. JOURNAL OF MEDICINAL CHEMISTRY
- New perspectives for synergy research with the “omic”-technologies
- (2009) G. Ulrich-Merzenich et al. PHYTOMEDICINE
- Drug Interactions with Natural Products at the Blood Brain Barrier
- (2008) Gert Fricker CURRENT DRUG METABOLISM
- Evolutionary Advantage and Molecular Modes of Action of Multi-Component Mixtures Used in Phytomedicine
- (2008) Michael Wink CURRENT DRUG METABOLISM
- Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)
- (2008) Vera Rosenkranz et al. MOLECULES
- IAP-targeted therapies for cancer
- (2008) E C LaCasse et al. ONCOGENE
- Antiproliferative effects of the major tea polyphenol, (−)-epigallocatechin gallate and retinoic acid in cervical adenocarcinoma
- (2007) Msatoshi Yokoyama et al. GYNECOLOGIC ONCOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started