Spatial RNA Sequencing Identifies Robust Markers of Vulnerable and Resistant Human Midbrain Dopamine Neurons and Their Expression in Parkinson’s Disease

Human‐Specific Transcriptome of Ventral and Dorsal Midbrain Dopamine Neurons

(2020) Jimena Monzón‐Sandoval et al.   ANNALS OF NEUROLOGY

Identification of potential diagnostic biomarkers for Parkinson's disease

(2019) Fenghua Jiang et al.   FEBS Open Bio

Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease

(2018) Paul W. Hook et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pluripotent stem cell-based therapy for Parkinson’s disease: Current status and future prospects

(2018) Kai-C. Sonntag et al.   PROGRESS IN NEUROBIOLOGY

Exome sequencing in an Italian family with Alzheimer’s disease points to a role for seizure-related gene 6 (SEZ6) rare variant R615H

(2018) Lara Paracchini et al.   Alzheimers Research & Therapy

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation

(2017) Sara Nolbrant et al.   Nature Protocols

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

(2017) Andrea Forero et al.   Frontiers in Cellular Neuroscience

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

(2016) Gioele La Manno et al.   CELL

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease

(2016) Payam Emami Khoonsari et al.   PLoS One

Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling

(2016) Susanne Nichterwitz et al.   Nature Communications

Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation

(2016) Elsa Vera et al.   Cell Reports

De novo variants in sporadic cases of childhood onset schizophrenia

(2015) Amirthagowri Ambalavanan et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The human transcriptome across tissues and individuals

(2015) M. Mele et al.   SCIENCE

Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

(2015) Hocine Rekaik et al.   Cell Reports

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex

(2014) Alex A Pollen et al.   NATURE BIOTECHNOLOGY

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

(2014) Carolina Cebrián et al.   Nature Communications

Sox6 and Otx2 Control the Specification of Substantia Nigra and Ventral Tegmental Area Dopamine Neurons

(2014) Lia Panman et al.   Cell Reports

Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling

(2014) Jean-Francois Poulin et al.   Cell Reports

Rgs6 is Required for Adult Maintenance of Dopaminergic Neurons in the Ventral Substantia Nigra

(2014) Panojot Bifsha et al.   PLoS Genetics

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease

(2013) Zinovia Kefalopoulou et al.   JAMA Neurology

Cadherins and neuropsychiatric disorders

(2012) Christoph Redies et al.   BRAIN RESEARCH

Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment

(2012) Yosif M. Ganat et al.   JOURNAL OF CLINICAL INVESTIGATION

GIRK2 expression in dopamine neurons of the substantia nigra and ventral tegmental area

(2012) Stefanie Reyes et al.   JOURNAL OF COMPARATIVE NEUROLOGY

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

(2012) Annelies Van Hoecke et al.   NATURE MEDICINE

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

(2011) Sonja Kriks et al.   NATURE

Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults

(2011) Daniel Alvarez-Fischer et al.   NATURE NEUROSCIENCE

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

(2009) Michela Di Salvio et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Neuronal cell replacement in Parkinson’s disease

(2009) E. Hedlund et al.   JOURNAL OF INTERNAL MEDICINE

Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease

(2009) Yanping Li et al.   NATURE NEUROSCIENCE

Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression

(2009) Kambiz N Alavian et al.   Neural Development

Calcium signaling and neurodegenerative diseases

(2009) Ilya Bezprozvanny   TRENDS IN MOLECULAR MEDICINE

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology

(2008) Filip Simunovic et al.   BRAIN

Analysis of Gene Expression in Parkinson's Disease: Possible Involvement of Neurotrophic Support and Axon Guidance in Dopaminergic Cell Death

(2008) Koen Bossers et al.   BRAIN PATHOLOGY