4.7 Letter

Intensified antibody response elicited by boost suggests immune memory in individuals administered two doses of SARS-CoV-2 inactivated vaccine

Journal

EMERGING MICROBES & INFECTIONS
Volume 10, Issue 1, Pages 1112-1115

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/22221751.2021.1937328

Keywords

SARS-CoV-2; inactivated vaccine; immune memory; COVID-19; antibody waning

Funding

  1. Applied Basic Research Key Project of Yunnan [202003AC 100003,202003AC100009]
  2. National Key Research and Development Program of China [2020YFC0849700,2020YFC0860600]
  3. Program of Chinese Academy of Medicine Science [2020-I2M-2-014,2020HY320001]

Ask authors/readers for more resources

A study on individuals who received an inactivated SARS-CoV-2 vaccine showed a decrease in neutralizing antibodies over time, but the waning of antibodies does not necessarily indicate a loss of immunity.
Neutralizing antibodies in the subjects of an inactivated SARS-CoV-2 vaccine clinical trial showed a decreasing trend over months. An investigation studying the third immunization suggested that the waning of neutralizing antibodies in individuals administered two doses of inactivated vaccine does not mean the disappearance of immunity.

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