Distinct Immune Profiles of Exhausted Effector and Memory CD8+ T Cells in Individuals With Filarial Lymphedema

Flow cytometric analysis of cell lineage and immune activation markers using minimal amounts of human whole blood—Field method for remote settings

(2021) Sacha Horn et al.   JOURNAL OF IMMUNOLOGICAL METHODS

CCR5 and CCR5Δ32 in bacterial and parasitic infections: Thinking chemokine receptors outside the HIV box

(2020) Joel Henrique Ellwanger et al.   International Journal of Immunogenetics

Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases

(2020) Joel Henrique Ellwanger et al.   VIRUS RESEARCH

Decrease of T-cells exhaustion markers programmed cell death-1 and T-cell immunoglobulin and mucin domain-containing protein 3 and plasma IL-10 levels after successful treatment of chronic hepatitis C

(2020) Sylwia Osuch et al.   Scientific Reports

Helminth Induced Immunoregulation and Novel Therapeutic Avenue of Allergy

(2020) Birhanu Ayelign et al.   Journal of Asthma and Allergy

Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia (AML)

(2019) Bei Jia et al.   CANCER RESEARCH

Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment

(2019) Manuel Ritter et al.   PLoS Neglected Tropical Diseases

Strategies to Control Human Lymphatic Filarial Infection: Tweaking Host’s Immune System

(2019) Puvvada Kalpana Murthy   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Cytotoxic T-Lymphocyte–Associated Antigen 4 (CTLA-4) and Programmed Death 1 (PD-1) mediated regulation of mono- and dual functional CD4+ and CD8+ T-cell responses in a chronic helminth infection

(2019) Anuradha Rajamanickam et al.   INFECTION AND IMMUNITY

Wuchereria bancrofti infection is linked to systemic activation of CD4 and CD8 T cells

(2019) Inge Kroidl et al.   PLoS Neglected Tropical Diseases

The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy

(2019) Huimin Du et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CD39 and immune regulation in a chronic helminth infection: The puzzling case of Mansonella ozzardi

(2018) Nathália F. Lima et al.   PLoS Neglected Tropical Diseases

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

PD-1 regulates KLRG1+group 2 innate lymphoid cells

(2017) Samuel Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Excess Lymphangiogenesis Cooperatively Induced by Macrophages and CD4+ T Cells Drives the Pathogenesis of Lymphedema

(2016) Fusa Ogata et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors

(2016) Ameet K. Mishra et al.   Oncotarget

Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression

(2015) Kiera L. Clayton et al.   JOURNAL OF VIROLOGY

Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

(2015) Kathrin Arndts et al.   Parasites & Vectors

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

Interleukin-10- and Transforming Growth Factor β-Independent Regulation of CD8+T Cells Expressing Type 1 and Type 2 Cytokines in Human Lymphatic Filariasis

(2014) Rajamanickam Anuradha et al.   Clinical and Vaccine Immunology

Expansion of Parasite-Specific CD4+ and CD8+ T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis

(2014) Rajamanickam Anuradha et al.   PLoS Neglected Tropical Diseases

Progress and Impact of 13 Years of the Global Programme to Eliminate Lymphatic Filariasis on Reducing the Burden of Filarial Disease

(2014) K. D. Ramaiah et al.   PLoS Neglected Tropical Diseases

T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection

(2014) Marcus Buggert et al.   PLoS Pathogens

Immunology of lymphatic filariasis

(2013) S. Babu et al.   PARASITE IMMUNOLOGY

PD-1 Dependent Exhaustion of CD8+ T Cells Drives Chronic Malaria

(2013) Joshua M. Horne-Debets et al.   Cell Reports

Reduced Cellular Susceptibility to In Vitro HIV Infection Is Associated with CD4+ T Cell Quiescence

(2012) Catherine M. Card et al.   PLoS One

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

(2012) M. A. Paley et al.   SCIENCE

Immunopathogenesis of lymphatic filarial disease

(2012) Subash Babu et al.   Seminars in Immunopathology

Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti

(2012) Kathrin Arndts et al.   PLoS Neglected Tropical Diseases

TLRs, Treg, and B Cells, an Interplay of Regulation during Helminth Infection

(2012) Isis Ludwig-Portugall et al.   Frontiers in Immunology

Lymphatic Dysfunction Impairs Antigen-Specific Immunization, but Augments Tissue Swelling Following Contact with Allergens

(2011) Makoto Sugaya et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Elevated Levels of Plasma Angiogenic Factors Are Associated with Human Lymphatic Filarial Infections

(2010) Sasisekhar Bennuru et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Induction of immunoglobulin G4 in human filariasis: an indicator of immunoregulation

(2010) T. Adjobimey et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

T-cell exhaustion: characteristics, causes and conversion

(2010) John S. Yi et al.   IMMUNOLOGY

CCR5: From Natural Resistance to a New Anti-HIV Strategy

(2010) Lucia Lopalco   Viruses-Basel

Pathways of memory CD8+ T-cell development

(2009) Oliver Bannard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pronounced Phenotype in Activated Regulatory T Cells during a Chronic Helminth Infection

(2009) L. E. Layland et al.   JOURNAL OF IMMUNOLOGY

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Filariasis and lymphoedema

(2009) K. M. PFARR et al.   PARASITE IMMUNOLOGY

Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells

(2009) Subash Babu et al.   PLoS Neglected Tropical Diseases

Lymphangiogenesis and Lymphatic Remodeling Induced by Filarial Parasites: Implications for Pathogenesis

(2009) Sasisekhar Bennuru et al.   PLoS Pathogens

The Chemokine Receptor CCR5 Plays a Key Role in the Early Memory CD8+ T Cell Response to Respiratory Virus Infections

(2008) Jacob E. Kohlmeier et al.   IMMUNITY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased Loss of CCR5+ CD45RA- CD4+ T Cells in CD8+ Lymphocyte-Depleted Simian Immunodeficiency Virus-Infected Rhesus Monkeys

(2008) R. S. Veazey et al.   JOURNAL OF VIROLOGY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY