4.6 Article

Insights into Shape-Based Silver Nanoparticles: A Weapon to Cope with Pathogenic Attacks

Journal

ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Volume 9, Issue 37, Pages 12476-12507

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.1c03797

Keywords

Green synthesis; AgNPs; Shape; Size; Drug delivery; MDR pathogens

Funding

  1. Human Resources Development Program of the Korea Institute of Energy Technology Evaluation and Planning (KETEP) - Korean Government Ministry of Trade, Industry and Energy [20194030202470]
  2. Technology Development Program to Solve Climate Changes of the National Research Foundation - Ministry of Science and ICT [2016M1A2A2936784]

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Silver nanoparticles have resourceful medicinal properties and unique optoelectronic characteristics, making them suitable for healthcare applications. However, their potential toxicity and hazards should be considered before use, and further research is needed to ensure safety and quality in human health complications. The characterization of nanoparticles for implementation in human life is still in its infancy, and global guidelines are needed for future construction.
Silver nanoparticles (AgNPs) can be used to treat many clinical challenges due to their resourceful medicinal properties present in them. Moreover, AgNPs exhibits unique optoelectronic properties, distinct chemistry, high surface-to-volume ratio, and high avidity, making them principally suitable for healthcare applications. In the present perspective, size and shape-based AgNPs antimicrobial action are reviewed. Furthermore, the intrinsic features and plausible toxicity of AgNPs with emerging applications across daily life and healthcare categories are discussed. This perspective urges researchers to focus on the hazards of AgNPs before their utilization to deal with human diseases. Moreover, additional studies have been suggested concerning the sustainable engineering of nanoparticles toward safety and quality in human health complications. All these concerns are still considered a challenge because nanoparticle characterization is still in its infancy for implementation in human life. Finally, this perspective provides a scientific foundation for the construction of global accord guidelines in the future.

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