Aryl hydrocarbon receptor activation by Lactobacillus reuteri tryptophan metabolism alleviates Escherichia coli-induced mastitis in mice

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Targeting gut microbiota as a possible therapy for mastitis

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Dimethyl itaconate protects against lippolysacchride-induced mastitis in mice by activating MAPKs and Nrf2 and inhibiting NF-κB signaling pathways

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(2018) Veit Rothhammer et al.   NATURE

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(2018) Jose C Clemente et al.   BMJ-British Medical Journal

The role of the gut microbiome in systemic inflammatory disease

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Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome

(2018) Jane M. Natividad et al.   Cell Metabolism

Tryptophan, kynurenine, kynurenic acid concentrations and indoleamine 2,3-dioxygenase activity in serum and milk of dairy cows with subclinical mastitis caused by coagulase-negative staphylococci

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A tryptophan metabolite of the skin microbiota attenuates inflammation in patients with atopic dermatitis through the aryl hydrocarbon receptor

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Consumption of Mediterranean versus Western Diet Leads to Distinct Mammary Gland Microbiome Populations

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Cow-to-mouse fecal transplantations suggest intestinal microbiome as one cause of mastitis

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Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages

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Ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry MS E -based untargeted milk metabolomics in dairy cows with subclinical or clinical mastitis

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Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice

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Feedback control of AHR signalling regulates intestinal immunity

(2017) Chris Schiering et al.   NATURE

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

The Human Intestinal Microbiome in Health and Disease

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TRAM-Derived Decoy Peptides inhibits the inflammatory response in mouse mammary epithelial cells and a mastitis model in mice

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Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota

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Aryl hydrocarbon receptor control of a disease tolerance defence pathway

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Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

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ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Host-Gut Microbiota Metabolic Interactions

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Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

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The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation

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