CRISPR/Cas9 modified An. gambiae carrying kdr mutation L1014F functionally validate its contribution in insecticide resistance and combined effect with metabolic enzymes

Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance

(2021) Andrew Hammond et al.   PLoS Genetics

The presence of knockdown resistance mutations reduces male mating competitiveness in the major arbovirus vector, Aedes aegypti

(2021) Lisa M. Rigby et al.   PLoS Neglected Tropical Diseases

Using CRISPR/Cas9 genome modification to understand the genetic basis of insecticide resistance: Drosophila and beyond

(2020) Vassilis Douris et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

A high throughput multi-locus insecticide resistance marker panel for tracking resistance emergence and spread in Anopheles gambiae

(2019) Eric R. Lucas et al.   Scientific Reports

A sensory appendage protein protects malaria vectors from pyrethroids

(2019) Victoria A. Ingham et al.   NATURE

Disruption of nicotinic acetylcholine receptor α6 mediated by CRISPR/Cas9 confers resistance to spinosyns in Plutella xylostella

(2019) Xingliang Wang et al.   PEST MANAGEMENT SCIENCE

Functional genetic validation of key genes conferring insecticide resistance in the major African malaria vector,Anopheles gambiae

(2019) Adriana Adolfi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insect cuticle: a critical determinant of insecticide resistance

(2018) Vasileia Balabanidou et al.   Current Opinion in Insect Science

Insecticide resistance in Anopheles gambiae from the northern Democratic Republic of Congo, with extreme knockdown resistance (kdr) mutation frequencies revealed by a new diagnostic assay

(2018) Amy Lynd et al.   MALARIA JOURNAL

WHO cone bio-assays of classical and new-generation long-lasting insecticidal nets call for innovative insecticides targeting the knock-down resistance mechanism in Benin

(2017) Marius Allossogbe et al.   MALARIA JOURNAL

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector,Aedes aegypti

(2017) Ming Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does resistance really carry a fitness cost?

(2017) Richard H ffrench-Constant et al.   Current Opinion in Insect Science

Resistance mutation conserved between insects and mites unravels the benzoylurea insecticide mode of action on chitin biosynthesis

(2016) Vassilis Douris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification, Validation, and Application of Molecular Diagnostics for Insecticide Resistance in Malaria Vectors

(2016) Martin J. Donnelly et al.   TRENDS IN PARASITOLOGY

Insecticide Resistance in Mosquitoes: Impact, Mechanisms, and Research Directions

(2015) Nannan Liu   Annual Review of Entomology

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

(2015) S. Bhatt et al.   NATURE

Evolution of insecticide resistance diagnostics in malaria vectors

(2015) D. Weetman et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Relationship Between kdr Mutation and Resistance to Pyrethroid and DDT Insecticides in Natural Populations of Anopheles gambiae

(2015) L. Reimer et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Dose-Response Analysis Using R

(2015) Christian Ritz et al.   PLoS One

Metabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae

(2014) Sara N. Mitchell et al.   PLoS One

Adaptive introgression between Anopheles sibling species eliminates a major genomic island but not reproductive isolation

(2014) Chris S. Clarkson et al.   Nature Communications

A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector

(2014) Jacob M Riveron et al.   GENOME BIOLOGY

Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso

(2013) Rachel M. Kwiatkowska et al.   GENE

Insecticide Resistance Alleles Affect Vector Competence of Anopheles gambiae s.s. for Plasmodium falciparum Field Isolates

(2013) Haoues Alout et al.   PLoS One

Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae

(2012) C. M. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Can piperonyl butoxide enhance the efficacy of pyrethroids against pyrethroid-resistant Aedes aegypti?

(2011) Georgina Bingham et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Field, Genetic, and Modeling Approaches Show Strong Positive Selection Acting upon an Insecticide Resistance Mutation in Anopheles gambiae s.s.

(2010) A. Lynd et al.   MOLECULAR BIOLOGY AND EVOLUTION