The biophysical principles underpinning muco-trapping functions of antibodies

LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus

(2020) Holly A. Schroeder et al.   Mucosal Immunology

Antibody-mediated trapping in biological hydrogels is governed by sugar-sugar hydrogen bonds

(2020) Jennifer L. Schiller et al.   Acta Biomaterialia

Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF‐α and IL‐8 secretion

(2020) Abhinav Sharma et al.   BIOTECHNOLOGY AND BIOENGINEERING

Broadly Neutralizing Antibodies against HIV: Back to Blood

(2019) Amir Dashti et al.   TRENDS IN MOLECULAR MEDICINE

Robust antigen-specific tuning of the nanoscale barrier properties of biogels using matrix-associating IgG and IgM antibodies

(2019) Jennifer L. Schiller et al.   Acta Biomaterialia

ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus

(2018) Bing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Herpes simplex virus-binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition

(2018) Holly A. Schroeder et al.   Mucosal Immunology

The Role of the Polymeric Immunoglobulin Receptor and Secretory Immunoglobulins during Mucosal Infection and Immunity

(2018) Holly Turula et al.   Viruses-Basel

A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

(2017) Jay Newby et al.   Nature Communications

Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus

(2016) Christine E. Henry et al.   Acta Biomaterialia

Influenza-binding antibodies immobilise influenza viruses in fresh human airway mucus

(2016) Ying-Ying Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

(2016) B M Gunn et al.   Mucosal Immunology

Antibody responses to envelope glycoproteins in HIV-1 infection

(2015) Dennis R Burton et al.   NATURE IMMUNOLOGY

Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus

(2015) Timothy Wessler et al.   ACS Infectious Diseases

Modeling of Virion Collisions in Cervicovaginal Mucus Reveals Limits on Agglutination as the Protective Mechanism of Secretory Immunoglobulin A

(2015) Alex Chen et al.   PLoS One

Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion

(2014) Alex Chen et al.   BIOPHYSICAL JOURNAL

Antibody blocks acquisition of bacterial colonization through agglutination

(2014) A M Roche et al.   Mucosal Immunology

IgG in cervicovaginal mucus traps HSV and prevents vaginal Herpes infections

(2014) Y-Y Wang et al.   Mucosal Immunology

Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

(2014) Scott A. McKinley et al.   PLoS One

Nanoparticle diffusion in respiratory mucus from humans without lung disease

(2013) Benjamin S. Schuster et al.   BIOMATERIALS

Differential Binding of IgG and IgA to Mucus of the Female Reproductive Tract

(2013) Kelly M. Fahrbach et al.   PLoS One

Mucus Properties and Goblet Cell Quantification in Mouse, Rat and Human Ileal Peyer's Patches

(2013) Anna Ermund et al.   PLoS One

Secretory immunity with special reference to the oral cavity

(2013) Per Brandtzaeg   Journal of Oral Microbiology

Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

(2012) E. M. Hur et al.   BLOOD

Simultaneous Approach Using Systemic, Mucosal and Transcutaneous Routes of Immunization For Development of Protective HIV-1 Vaccines

(2011) I.M. Belyakov et al.   CURRENT MEDICINAL CHEMISTRY

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Antibody-based protection against HIV infection by vectored immunoprophylaxis

(2011) Alejandro B. Balazs et al.   NATURE

A new synthesis for antibody-mediated immunity

(2011) Arturo Casadevall et al.   NATURE IMMUNOLOGY

Micro- and macrorheology of mucus

(2009) Samuel K. Lai et al.   ADVANCED DRUG DELIVERY REVIEWS

The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles

(2009) Jung Soo Suk et al.   BIOMATERIALS

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

Human Immunodeficiency Virus Type 1 Is Trapped by Acidic but Not by Neutralized Human Cervicovaginal Mucus

(2009) S. K. Lai et al.   JOURNAL OF VIROLOGY

Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses

(2009) S. K. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

(2009) J. P. Celli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA