A comparison study of multivariate fixed models and Gene Association with Multiple Traits (GAMuT) for next-generation sequencing

A Statistical Approach for Testing Cross-Phenotype Effects of Rare Variants

(2016) K. Alaine Broadaway et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Uncovering Local Trends in Genetic Effects of Multiple Phenotypes via Functional Linear Models

(2016) Olga A. Vsevolozhskaya et al.   GENETIC EPIDEMIOLOGY

Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions

(2016) Ruzong Fan et al.   GENETIC EPIDEMIOLOGY

A Comparison Study of Fixed and Mixed Effect Models for Gene Level Association Studies of Complex Traits

(2016) Ruzong Fan et al.   GENETIC EPIDEMIOLOGY

Pleiotropy Analysis of Quantitative Traits at Gene Level by Multivariate Functional Linear Models

(2015) Yifan Wang et al.   GENETIC EPIDEMIOLOGY

Meta-analysis of Complex Diseases at Gene Level with Generalized Functional Linear Models

(2015) R. Fan et al.   GENETICS

Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models

(2015) Ruzong Fan et al.   GENETICS

Gene Level Meta-Analysis of Quantitative Traits by Functional Linear Models

(2015) Ruzong Fan et al.   GENETICS

Region-Based Association Test for Familial Data under Functional Linear Models

(2015) Gulnara R. Svishcheva et al.   PLoS One

Generalized Functional Linear Models for Gene-Based Case-Control Association Studies

(2014) Ruzong Fan et al.   GENETIC EPIDEMIOLOGY

A Comparison of Multivariate Genome-Wide Association Methods

(2014) Tessel E. Galesloot et al.   PLoS One

Functional Analysis of Variance for Association Studies

(2014) Olga A. Vsevolozhskaya et al.   PLoS One

Searching for missing heritability: Designing rare variant association studies

(2014) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence Kernel Association Tests for the Combined Effect of Rare and Common Variants

(2013) Iuliana Ionita-Laza et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Functional Linear Models for Association Analysis of Quantitative Traits

(2013) Ruzong Fan et al.   GENETIC EPIDEMIOLOGY

Meta-analysis of gene-level tests for rare variant association

(2013) Dajiang J Liu et al.   NATURE GENETICS

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

Optimal Unified Approach for Rare-Variant Association Testing with Application to Small-Sample Case-Control Whole-Exome Sequencing Studies

(2012) Seunggeun Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Smoothed functional principal component analysis for testing association of the entire allelic spectrum of genetic variation

(2012) Li Luo et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

PSEA: Phenotype Set Enrichment Analysis-A New Method for Analysis of Multiple Phenotypes

(2012) Janina S. Ried et al.   GENETIC EPIDEMIOLOGY

Multivariate Phenotype Association Analysis by Marker-Set Kernel Machine Regression

(2012) Arnab Maity et al.   GENETIC EPIDEMIOLOGY

Quantitative trait locus analysis for next-generation sequencing with the functional linear models

(2012) Li Luo et al.   JOURNAL OF MEDICAL GENETICS

MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS

(2012) Paul F. O’Reilly et al.   PLoS One

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Abundant Pleiotropy in Human Complex Diseases and Traits

(2011) Shanya Sivakumaran et al.   AMERICAN JOURNAL OF HUMAN GENETICS

PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies

(2011) Jie Huang et al.   BIOINFORMATICS

Association studies for next-generation sequencing

(2011) L. Luo et al.   GENOME RESEARCH

Network properties of human disease genes with pleiotropic effects

(2010) Sreenivas Chavali et al.   BMC Systems Biology

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

Next-generation DNA sequencing techniques

(2009) Wilhelm J. Ansorge   New Biotechnology

Next-Generation DNA Sequencing Methods

(2008) Elaine R. Mardis   Annual Review of Genomics and Human Genetics

A multivariate test of association

(2008) Manuel A. R. Ferreira et al.   BIOINFORMATICS

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY