Article
Food Science & Technology
Cathrine Finne Kure, Solveig Langsrud, Trond Moretro
Summary: The study assesses the fungicidal effect of a H2O2 mist generating system on food-related mould spores dried on stainless steel. Results show >3 log reduction in mould spores after exposure to H2O2 mist for 2 or 4 hours, with raw meat juice having an adverse effect on Penicillium and Mucor in some tests. The research confirms the efficiency of H2O2 mist in reducing food-related mould spores on surfaces.
Article
Chemistry, Multidisciplinary
Michael K. Bellas, Adam J. Matzger
Summary: This article presents an efficient method for the discovery of peroxosolvates, which has been applied to discover the first ternary cocrystal comprising only energetic components.
CHEMICAL COMMUNICATIONS
(2022)
Article
Public, Environmental & Occupational Health
B. H. Ogilvie, A. Solis-Leal, J. B. Lopez, B. D. Poole, R. A. Robison, B. K. Berges
Summary: This study found that three commercially available quaternary ammonium compound (Quat) disinfectants and one laboratory-made 0.2% benzalkonium chloride solution can completely inactivate SARS-CoV-2 within a short period of time, even in the presence of a soil load or when diluted in hard water, indicating their potential usefulness in controlling the spread of SARS-CoV-2 in hospitals and the community.
JOURNAL OF HOSPITAL INFECTION
(2021)
Article
Chemistry, Multidisciplinary
Yanling You, Ya-Xuan Zhu, Junjie Jiang, Zhixin Chen, Chenyao Wu, Zhimin Zhang, Han Lin, Jianlin Shi
Summary: In this study, a new two-dimensional iodine nanomaterial called iodinene was proposed for the treatment of infectious diseases in vivo. Iodinene demonstrated enhanced antibacterial efficacy against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa by in situ production of active HIO and I2 molecules via allotropic transformation. The in vivo results further confirmed the desirable antibacterial efficacy of iodinene in treating bacterial wound infection and pneumonia.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Nanoscience & Nanotechnology
Yuanzhu Zhao, Lina Wang, Richard Malpass-Evans, Neil B. McKeown, Mariolino Carta, John P. Lowe, Catherine L. Lyall, Remi Castaing, Philip J. Fletcher, Gabriele Kociok-Kohn, Jannis Wenk, Zhenyu Guo, Frank Marken
Summary: In this study, graphitic carbon nitride (g-C3N4) was embedded into a polymer host to create recoverable photocatalysts with enhanced hydrogen peroxide production.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Engineering, Environmental
Andrea Hicks, Sila Temizel-Sekeryan, Wissam Kontar, Ramin Ghamkhar, Monica Rodriguez Morris
Summary: The COVID-19 pandemic is expected to last at least 18 months, highlighting a critical shortage of PPE in the United States. Adequate respiratory protection is essential, with reusable options potentially being more cost-effective.
RESOURCES CONSERVATION AND RECYCLING
(2021)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Microbiology
Rhonda Walters, Allison Campolo, Elise Miller, Cindy McAnally, Manal Gabriel, Paul Shannon, Monica Crary
Summary: The efficacy of preservative-free disinfection systems against bacteria, fungi, and Acanthamoeba was evaluated. Clear Care and Clear Care Plus showed significantly greater disinfection efficacy against Acanthamoeba compared to the povidone-iodine-based Cleadew system. The antimicrobial efficacy was maintained regardless of the presence of contact lenses.
MICROBIOLOGY SPECTRUM
(2022)
Article
Chemistry, Physical
Chenghang Jiang, Yan-Fei Fei, Weiwei Xu, Zhikang Bao, Yizhen Shao, Shijie Zhang, Zhong-Ting Hu, Jianguo Wang
Summary: A m-Bi2O3/Ta2O5 electrocatalyst with high selectivity towards H2O2 has been successfully synthesized, exhibiting an outstanding selectivity of 94.7% compared to Ta2O5 (80.9%) and Bi2O3 (81.7%). The electrocatalyst also shows high H2O2 yield and Faraday Efficiency, and can efficiently deactivate bacteria. This study presents a high-selective electrocatalyst for the two-electron pathway of oxygen reduction reaction and provides a new perspective for electrocatalyst design.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Ophthalmology
Anna A. Tichenor, Stacey S. Cofield, Drew Gann, Marian Elder, Alison Ng, Karen Walsh, Lyndon W. Jones, Jason J. Nichols
Summary: A retrospective study comparing the frequency of contact lens complications between hydrogen peroxide and multipurpose solution users found no significant differences, but showed that multipurpose solution users were more likely to report discomfort.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2021)
Article
Engineering, Environmental
Lei Wang, Yi Chen, Baiyang Chen, Jie Yang
Summary: This study showed that reduced oxygen mainly generates center dot OH, and photolysis products can trigger the formation of H2O2 under 254 nm UV. Additionally, evidence of direct photolysis-induced indirect photolysis phenomenon was presented, along with a comprehensive methodology to identify the presence and sources of radicals.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Huaicheng Zhang, Shudi Zhao, Aimin Li, Kaiqin Bian, Shanqi Shen, Meng Tao, Peng Shi
Summary: The researchers systematically studied the structure-dependent antimicrobial mechanism of QARs and synthesized a new resin, Ac-81, with a surficial antibacterial design, which exhibited better antimicrobial efficiency and higher contaminant removal potential. Ac-81 showed remarkable broad-spectrum antibacterial effects against various bacteria in simulated and actual water, significantly improving water quality by reducing contaminants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Green & Sustainable Science & Technology
Yijun Shi, Yunkun Qian, Jun Guo, Mengjun Mao, Dong An
Summary: A novel photoelectrochemical process (PEC/E-H2O2) was adopted to improve disinfection efficiency in distributed water treatment systems using clean energy. The process consumed low energy and effectively eliminated E. coli under simulated solar conditions. The in-situ generated H2O2 enhanced the oxidation of the photoelectrochemical system and resulted in a higher inactivation rate of E. coli compared to traditional methods. The study provides a promising alternative disinfection process for drinking water treatment.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Nanoscience & Nanotechnology
Qingyan Chen, Kai Zhao, Guoping Li, Jiyue Luo, Xin Li, Yingjie Zeng, Xiao-mao Wang
Summary: Given the increasing demand for drinking water purifiers, researchers have successfully developed highly permeable membranes with strong antimicrobial properties. These membranes, created through chemical grafting of quaternary ammonium salt molecules onto biodegradable polylactic acid substrates, exhibit excellent antimicrobial efficiency and high water filtration rates.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Medicine, General & Internal
Veronica Romano, Donato Di Gennaro, Anna Maria Sacco, Enrico Festa, Emanuela Roscetto, Morena Anna Basso, Tiziana Ascione, Giovanni Balato
Summary: This study evaluated the cytotoxicity of solutions containing povidone-iodine (PI) and hydrogen peroxide (H2O2), alone or in combination. The results showed that the toxicity of all tested solutions increased as exposure time increased, except for 0.3% PI solution, which exhibited the lowest toxicity. The combined solutions had lower cellular killing at 3 and 5 min compared to equal concentrations of H2O2, similar to PI solutions.
Article
Ophthalmology
Jaya Sowjanya Siddireddy, Ajay K. Vijay, Jacqueline Tan, Mark Willcox
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2020)
Article
Ophthalmology
Ajay Kumar Vijay, Hua Zhu, Mark Willcox, Howard Ketelson, Fiona Stapleton
CONTACT LENS & ANTERIOR EYE
(2020)
Article
Environmental Sciences
Binod Rayamajhee, Dinesh Subedi, Seoyoung Won, Jamie (Jung Yun) Kim, Ajay Vijay, Jacqueline Tan, Fiona L. Henriquez, Mark Willcox, Nicole A. Carnt
Review
Ophthalmology
Gauri Shankar Shrestha, Ajay Kumar Vijay, Fiona Stapleton, Fiona L. Henriquez, Nicole Carnt
Summary: Pseudomonas aeruginosa and Staphylococcus aureus are the dominant bacteria isolated from patients with contact lens-related bacterial keratitis. This review explores the clinical and immunological features associated with these bacteria, aiming to deepen understanding of their impact on keratitis outcomes.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Jacqueline Tan, Jaya Sowjanya Siddireddy, Katherine Wong, Qing Shen, Ajay Kumar Vijay, Fiona Stapleton
Summary: The study demonstrates the effectiveness of Smart Touch Technology packaging in reducing bacterial contamination of contact lenses, with silicone hydrogel lenses being more prone to contamination compared to hydrogel lenses.
OPTOMETRY AND VISION SCIENCE
(2021)
Article
Ophthalmology
Fiona Stapleton, May Bakkar, Nicole Carnt, Robin Chalmers, Ajay Kumar Vijay, Sanjay Marasini, Alison Ng, Jacqueline Tan, Heidi Wagner, Craig Woods, James S. Wolffsohn
Summary: Contact lens-related complications are common and can affect wearers in various ways, including corneal infection, inflammation, metabolic conditions, mechanical issues, toxic and allergic disorders, tear resurfacing disorders/dry eye, and discomfort. It is important to understand the classification, epidemiology, pathophysiology, management, and prevention of these complications in order to optimize contact lens wear and address any related issues effectively.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Parthasarathi Kalaiselvan, Shyam Sunder Tummanapalli, Ajay Kumar Vijay, Prateek Bahl, Chandini Raina MacIntyre, Mark D. P. Willcox
Summary: This study demonstrated the effectiveness of face masks in reducing microbial transmission in laboratory tests, with seven-layer masks being particularly effective at preventing the spread of S. aureus in various aerosol particle sizes. However, face masks become contaminated quickly during wear, suggesting that they should be replaced regularly or properly washed if they are to be reused.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2022)
Article
Infectious Diseases
Madeeha Afzal, Ajay Kumar Vijay, Fiona Stapleton, Mark D. P. Willcox
Summary: Staphylococcus aureus isolates exhibited varying levels of resistance to antibiotics and disinfecting solutions, with microbial keratitis strains commonly showing resistance to multiple drugs. Strains from Australia were generally more susceptible to antibiotics compared to those from the USA, highlighting regional differences in resistance patterns.
Article
Ophthalmology
Parthasarathi Kalaiselvan, Muhammad Yasir, Ajay Kumar Vijay, Mark D. P. Willcox, Shyam Tummanapalli
Summary: This study evaluated the persistence of disinfection of three different hand sanitizers. The results showed that hand sanitizers containing capric acid or alcohol had better microbial inhibitory effects, which could help reduce the spread of microbes.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Review
Ophthalmology
Fiona Stapleton, Gauri S. Shrestha, Ajay K. Vijay, Nicole Carnt
Summary: This review examines the epidemiology of infectious keratitis and the differences between CL-related and non-CL-related diseases in terms of disease incidence, causative organisms, and virulence characteristics. The study found that there are differences in the epidemiology and characteristics of causative organisms between the two groups, but less evidence to support differences in the ocular surface microbiome, genetics, and disease pathways. However, genetic variations in the host immune profile are implicated in the onset and severity of infectious keratitis in both CL and non-CL wearers. Improvements in metabolomics, proteomics, and genomics technologies will further enhance our understanding of the interactions between CL, the ocular surface, host immune profile, and the microbial environment, potentially leading to more personalized approaches in disease management.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2022)
Article
Infectious Diseases
Parthasarathi Kalaiselvan, Muhammad Yasir, Rajesh Kuppusamy, Mark Willcox, Ajay Kumar Vijay
Summary: This study evaluated the efficacy of evaporated essential oils in reducing the numbers of culturable aerosolized coronavirus, bacterium, and fungus. The results showed that essential oil vapors were able to significantly reduce viable numbers of aerosolized coronavirus, bacteria, and fungal spores.
Article
Infectious Diseases
Madeeha Afzal, Ajay Kumar Vijay, Fiona Stapleton, Mark D. P. Willcox
Summary: Staphylococcus aureus is a major cause of ocular infections and non-infectious corneal infiltrative events. This study sequenced the whole genomes of ocular isolates from USA and Australia and identified specific virulence factors associated with the pathogenicity of these isolates. Infectious strains were found to have a higher presence of virulence genes involved in adhesion, immune evasion, and serine protease enzymes. Comparison with non-ocular isolates revealed differences in the genetic composition of ocular strains.
Article
Microbiology
Madeeha Afzal, Ajay Kumar Vijay, Fiona Stapleton, Mark Willcox
Summary: Staphylococcus aureus isolates in ocular infections show resistance to ciprofloxacin due to genetic mutations in QRDRs (gyrA and parC) and norB, suggesting that these are the common reasons for ciprofloxacin resistance.
Article
Infectious Diseases
Umme Laila Urmi, Samuel Attard, Ajay Kumar Vijay, Mark D. P. Willcox, Naresh Kumar, Salequl Islam, Rajesh Kuppusamy
Summary: The development of potent antiviral agents is crucial for combating viral infections worldwide. In this study, the antiviral potential of 17 peptidomimetic compounds was evaluated against MHV-1 and HSV-1. Compounds 11 and 14 showed the most potent inhibitory effects, and they were found to directly influence the viral envelope. These findings suggest that peptidomimetic compounds could offer a new approach for the development of potent antiviral agents.