Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza

Respiratory Barrier as a Safeguard and Regulator of Defense Against Influenza A Virus and Streptococcus pneumoniae

(2020) Kim S. LeMessurier et al.   Frontiers in Immunology

Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis

(2020) Norberto Gonzalez-Juarbe et al.   Cell Reports

Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways

(2020) Vicky Sender et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane perforation by the pore-forming toxin pneumolysin

(2019) Martin Vögele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of Pneumococcal Surface Protein A as a Vaccine Antigen against Secondary Streptococcus pneumoniae Challenge during Influenza A Infection

(2019) Sean Roberts et al.   Vaccines

Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia

(2018) Norberto Gonzalez-Juarbe et al.   Scientific Reports

Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing

(2017) Anukul T. Shenoy et al.   PLoS Pathogens

Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity

(2017) Greiciely O. Andre et al.   Frontiers in Microbiology

Novel Strategy To Protect against Influenza Virus-Induced Pneumococcal Disease without Interfering with Commensal Colonization

(2016) Christopher J. Greene et al.   INFECTION AND IMMUNITY

Free Sialic Acid Acts as a Signal That Promotes Streptococcus pneumoniae Invasion of Nasal Tissue and Nonhematogenous Invasion of the Central Nervous System

(2016) Brandon L. Hatcher et al.   INFECTION AND IMMUNITY

PcpA Promotes Higher Levels of Infection and Modulates Recruitment of Myeloid-Derived Suppressor Cells during Pneumococcal Pneumonia

(2016) Melissa M. Walker et al.   JOURNAL OF IMMUNOLOGY

Adhesion and invasion of Streptococcus pneumoniae to primary and secondary respiratory epithelial cells

(2016) Sara Novick et al.   Molecular Medicine Reports

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

(2016) Michael E Pacold et al.   Nature Chemical Biology

The Role of Streptococcus pneumoniae in Community-Acquired Pneumonia

(2016) Ronald Anderson et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of dual influenza and pneumococcal polysaccharide vaccination with influenza vaccination alone for preventing pneumonia and reducing mortality among the elderly: A meta-analysis

(2016) Yan-Yang Zhang et al.   Human Vaccines & Immunotherapeutics

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection

(2015) Austen Chen et al.   Clinical and Vaccine Immunology

Secreted multifunctional Glyceraldehyde-3-phosphate dehydrogenase sequesters lactoferrin and iron into cells via a non-canonical pathway

(2015) Anoop S. Chauhan et al.   Scientific Reports

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia

(2015) Norberto González-Juarbe et al.   PLoS Pathogens

Influenza Promotes Pneumococcal Growth during Coinfection by Providing Host Sialylated Substrates as a Nutrient Source

(2014) Steven J. Siegel et al.   Cell Host & Microbe

Identification of Glyceraldehyde 3-Phosphate Dehydrogenase Sequence and Expression Profiles in Tree Shrew (Tupaia belangeri)

(2014) Yu Zheng et al.   PLoS One

Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function

(2014) Armand O. Brown et al.   PLoS Pathogens

A modified surface killing assay (MSKA) as a functional in vitro assay for identifying protective antibodies against pneumococcal surface protein A (PspA)

(2013) Kristopher R. Genschmer et al.   VACCINE

Pneumococcal Surface Protein A Inhibits Complement Deposition on the Pneumococcal Surface by Competing with the Binding of C-Reactive Protein to Cell-Surface Phosphocholine

(2012) R. Mukerji et al.   JOURNAL OF IMMUNOLOGY

PcpA of Streptococcus pneumoniae mediates adherence to nasopharyngeal and lung epithelial cells and elicits functional antibodies in humans

(2012) M. Nadeem Khan et al.   MICROBES AND INFECTION

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Impact of the 2009 Influenza Pandemic on Pneumococcal Pneumonia Hospitalizations in the United States

(2011) Daniel M. Weinberger et al.   JOURNAL OF INFECTIOUS DISEASES

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

(2009) Carlos J. Orihuela et al.   JOURNAL OF CLINICAL INVESTIGATION

Pneumococcal Surface Protein A Contributes to SecondaryStreptococcus pneumoniaeInfection after Influenza Virus Infection

(2009) Quinton O. King et al.   JOURNAL OF INFECTIOUS DISEASES

Streptococcus pneumoniae Coinfection Is Correlated with the Severity of H1N1 Pandemic Influenza

(2009) Gustavo Palacios et al.   PLoS One

Streptococcus pneumoniae Surface Protein PcpA Elicits Protection against Lung Infection and Fatal Sepsis

(2008) D. T. Glover et al.   INFECTION AND IMMUNITY

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE