PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα

PdgfraandPdgfrbgenetically interact during craniofacial development

(2016) Neil McCarthy et al.   DEVELOPMENTAL DYNAMICS

Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype

(2016) Hanna Gladh et al.   PLoS One

A Point Mutation in PDGFRB Causes Autosomal-Dominant Penttinen Syndrome

(2015) Jennifer J. Johnston et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fgfr1 regulates development through the combinatorial use of signaling proteins

(2015) J. Richard Brewer et al.   GENES & DEVELOPMENT

Novel Overgrowth Syndrome Phenotype Due to Recurrent De Novo PDGFRB Mutation

(2015) Toshiki Takenouchi et al.   JOURNAL OF PEDIATRICS

Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

(2015) Harish N Vasudevan et al.   eLife

SRF Regulates Craniofacial Development through Selective Recruitment of MRTF Cofactors by PDGF Signaling

(2014) Harish N. Vasudevan et al.   DEVELOPMENTAL CELL

PI3K-mediated PDGFR  signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways

(2014) K. A. Fantauzzo et al.   GENES & DEVELOPMENT

Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice

(2013) F. Wiradjaja et al.   Disease Models & Mechanisms

bfb, a Novel ENU-Induced blebs Mutant Resulting from a Missense Mutation in Fras1

(2013) Kerry A. Miller et al.   PLoS One

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

A Critical Role for PDGFRα Signaling in Medial Nasal Process Development

(2013) Fenglei He et al.   PLoS Genetics

PDGFRa mutations in humans with isolated cleft palate

(2012) Sawitree Rattanasopha et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Whole mount nuclear fluorescent imaging: Convenient documentation of embryo morphology

(2012) Lisa L. Sandell et al.   GENESIS

Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1

(2011) A. M. Slavotinek et al.   JOURNAL OF MEDICAL GENETICS

Heterozygous Mutations of FREM1 Are Associated with an Increased Risk of Isolated Metopic Craniosynostosis in Humans and Mice

(2011) Lisenka E. L. M. Vissers et al.   PLoS Genetics

Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries

(2010) J. O. Bush et al.   GENES & DEVELOPMENT

FREM1 Mutations Cause Bifid Nose, Renal Agenesis, and Anorectal Malformations Syndrome

(2009) Anas M. Alazami et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Fras1/Frem Family of Extracellular Matrix Proteins: Structure, Function, and Association with Fraser Syndrome and the MouseblebPhenotype

(2008) Petros Petrou et al.   CONNECTIVE TISSUE RESEARCH

The PDGF-C regulatory region SNP rs28999109 decreases promoter transcriptional activity and is associated with CL/P

(2008) Sun J Choi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

The PDGF signaling pathway controls multiple steroid-producing lineages

(2008) J. Schmahl et al.   GENES & DEVELOPMENT

Sustained Platelet-Derived Growth Factor Receptor   Signaling in Osteoblasts Results in Craniosynostosis by Overactivating the Phospholipase C-  Pathway

(2008) A. Moenning et al.   MOLECULAR AND CELLULAR BIOLOGY

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS