Review
Nutrition & Dietetics
Shuting Li, Leying Hou, Siyu Zhu, Qian Yi, Wen Liu, Yang Zhao, Feitong Wu, Xue Li, An Pan, Peige Song
Summary: No consensus has been reached on the associations of lipid variability with cardiovascular diseases and all-cause mortality. This study found that variability in total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol is associated with an increased risk of cardiovascular diseases and all-cause mortality. The relationship between triglyceride variability and risk is inconclusive. These findings suggest that measuring and monitoring lipid variability could have important clinical implications for risk assessment of cardiovascular diseases and all-cause mortality.
Review
Public, Environmental & Occupational Health
Yan-Bo Zhang, Xiong-Fei Pan, Junxiang Chen, Anlan Cao, Lu Xia, Yuge Zhang, Jing Wang, Huiqi Li, Gang Liu, An Pan
Summary: This study found that adopting healthy lifestyles can reduce the risk of all-cause mortality, cardiovascular mortality, and incident cardiovascular diseases. The associations were significant and consistent across different continents, racial groups, and socioeconomic backgrounds. Given the significant health benefits, addressing multiple lifestyle risk factors should be a key strategy in reducing the global disease burden.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2021)
Article
Cardiac & Cardiovascular Systems
Bin Zhang, Zhi-Fei Li, Zhuo-Yu An, Li Zhang, Jing-Yi Wang, Meng-Di Hao, Yi-Jing Jin, Dong Li, An-Jian Song, Qiang Ren, Wen-Biao Chen
Summary: The study found that asthma patients have an increased risk of cardiovascular disease morbidity and mortality, as well as all-cause mortality. Female asthma patients have a higher risk of cardiovascular disease morbidity and all-cause mortality, and late-onset asthma patients have a higher risk of cardiovascular disease morbidity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Food Science & Technology
Rebecca-Evelyn Papp, Verena Hasenegger, Cem Ekmekcioglu, Lukas Schwingshackl
Summary: This meta-analysis suggests that a high intake of poultry is not associated with cardiovascular disease risk. Additionally, substituting red and/or processed meat with poultry could have a beneficial effect on overall mortality and the risk for cardiovascular diseases, coronary heart disease, and stroke.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Sina Naghshi, Mohammad Naemi, Omid Sadeghi, Manije Darooghegi Mofrad, Mehrasa Moezrad, Leila Azadbakht
Summary: This study aimed to investigate the association between calcium intake and mortality risk. The findings suggested that moderate intake of total and dietary calcium were inversely associated with mortality risk, while supplemental calcium intake showed no significant association. Nonlinear relationships were observed between calcium intake and all-cause, CVD, and cancer mortality risk.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Nutrition & Dietetics
Nikan Zargarzadeh, Seyed Mohammad Mousavi, Heitor O. Santos, Dagfinn Aune, Shirin Hasani-Ranjbar, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This study examined the potential dose-response relationship between legume consumption and mortality rates in the general population. The results showed that higher legume intake was associated with a reduced risk of all-cause and stroke mortality, but there was no significant association with cardiovascular disease, coronary heart disease, and cancer mortality.
ADVANCES IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Seyed Mohammad Mousavi, Nikan Zargarzadeh, Somaye Rigi, Emma Persad, Ana Beatriz Pizarro, Shirin Hasani-Ranjbar, Bagher Larijani, Walter C. Willett, Ahmad Esmaillzadeh
Summary: The study found that higher egg consumption was not associated with mortality from all causes, cardiovascular disease, coronary heart disease, stroke, or respiratory disease. However, it was associated with an increased risk of cancer mortality. Each additional egg per week consumption was associated with a 2% and 4% increased risk of all-cause and cancer mortality, respectively. The certainty of the evidence was rated as low to moderate.
ADVANCES IN NUTRITION
(2022)
Review
Sport Sciences
Yang Zhao, Fulan Hu, Yifei Feng, Xingjin Yang, Yang Li, Chunmei Guo, Quanman Li, Gang Tian, Ranran Qie, Minghui Han, Shengbing Huang, Xiaoyan Wu, Yanyan Zhang, Yuying Wu, Dechen Liu, Dongdong Zhang, Cheng Cheng, Ming Zhang, Yongli Yang, Xuezhong Shi, Jie Lu, Dongsheng Hu
Summary: The study suggests that at least 15 MET-h/week of cycling can effectively reduce the risk of cardiovascular disease mortality, while any level of cycling is beneficial for all-cause mortality.
Review
Geriatrics & Gerontology
Yang Peng, Guo-Chao Zhong, Xiaoli Zhou, Lijuan Guan, Lihua Zhou
Summary: This meta-analysis explored the associations of frailty with all-cause and cause-specific mortality. The findings revealed that frailty was significantly associated with an increased risk of all-cause mortality and was a strong predictor of cause-specific mortality from cardiovascular disease, cancer, and respiratory illness in community-dwelling adults. Further studies are needed to clarify the relationship between frailty and cause-specific mortality from dementia, infection, and COVID-19.
Review
Nutrition & Dietetics
Faina Wehrli, Petek E. Taneri, Arjola Bano, Lia Bally, Lauren C. Blekkenhorst, Weston Bussler, Brandon Metzger, Beatrice Minder, Marija Glisic, Taulant Muka, Hua Kern
Summary: The consumption of oats may reduce the risk of type 2 diabetes and all-cause mortality. However, there is no significant association between oat consumption and cardiovascular disease. Future studies should focus on standardizing methods for assessing oat intake and investigating the dose-dependent response of oat products on cardiometabolic outcomes.
Article
Gastroenterology & Hepatology
Natassia Tan, N. Ngu, T. Worland, T. Lee, T. Abrahams, K. Pandya, E. Freeman, N. Hannah, K. Gazelakis, R. G. Madden, K. D. Lynch, Z. Valaydon, S. Sood, A. Dev, S. Bell, A. Thompson, J. Ding, A. J. Nicoll, K. Liu, P. Gow, J. Lubel, W. Kemp, S. K. Roberts, A. Majeed
Summary: This study evaluated the epidemiology and clinical outcomes of primary sclerosing cholangitis (PSC) in Australia and compared them to the general population. The results showed that PSC patients had a higher risk of developing cirrhosis and death, especially from cholangiocarcinoma. Age and time from diagnosis were closely associated with disease severity and prognosis.
HEPATOLOGY INTERNATIONAL
(2022)
Review
Food Science & Technology
Sina Naghshi, Omid Sadeghi, Bagher Larijani, Ahmad Esmaillzadeh
Summary: There is considerable controversy regarding the association between milk and dairy consumption and mortality risk. This systematic review and meta-analysis found that high-fat milk consumption was significantly associated with a higher risk of all-cause, cardiovascular disease (CVD), and cancer mortality. However, total dairy consumption was associated with a lower risk of CVD mortality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Qiman Jin, Niannian Yang, Juan Dai, Yuanyuan Zhao, Xiaoxia Zhang, Jiawei Yin, Yaqiong Yan
Summary: This study found a significant association between sleep duration <5 hours or >9 hours and increased risks of all-cause and cardiovascular mortality. It was estimated that 187,000 cardiovascular disease events were attributable to short sleep duration and 947,000 cardiovascular disease events were attributable to long sleep duration.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Medicine, General & Internal
Marcin M. Nowak, Mariusz Niemczyk, Michal Florczyk, Marcin Kurzyna, Leszek Paczek
Summary: This meta-analysis found that statin use was associated with a significantly reduced risk of all-cause mortality in both cardiovascular disease and non-cardiovascular disease real-world cohorts.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Nutrition & Dietetics
Amir Bagheri, Sina Naghshi, Omid Sadeghi, Bagher Larijani, Ahmad Esmaillzadeh
Summary: The study found that higher dietary magnesium intake was associated with a reduced risk of all-cause and cancer mortality, but not CVD mortality. There were no significant associations between supplemental and total magnesium intakes with the risk of mortality. Linear dose-response analysis revealed that each additional intake of 100 mg/d of dietary magnesium was linked to a decreased risk of all-cause and cancer mortality.
ADVANCES IN NUTRITION
(2021)
Article
Gastroenterology & Hepatology
Edoardo Botteri, Giulia Peveri, Paula Berstad, Vincenzo Bagnardi, Sairah L. F. Chen, Torkjel M. Sandanger, Geir Hoff, Christina C. Dahm, Christian S. Antoniussen, Anne Tjonneland, Anne Kirstine Eriksen, Guri Skeie, Aurora Perez-Cornago, Jose Maria Huerta, Paula Jakszyn, Sophia Harlid, Bjoern Sundstroem, Aurelio Barricarte, Evelyn M. Monninkhof, Jeroen W. G. Derksen, Matthias B. Schulze, Bas Bueno-de-Mesquita, Maria-Jose Sanchez, Amanda J. Cross, Konstantinos K. Tsilidis, Maria Santucci De Magistris, Rudolf Kaaks, Verena Katzke, Joseph A. Rothwell, Nasser Laouali, Gianluca Severi, Pilar Amiano, Paolo Contiero, Carlotta Sacerdote, Marcel Goldberg, Mathilde Touvier, Heinz Freisling, Vivian Viallon, Elisabete Weiderpass, Elio Riboli, Marc J. Gunter, Mazda Jenab, Pietro Ferrari
Summary: This study investigated the impact of changes in lifestyle habits on the risk of colorectal cancer. The results showed that adhering to a healthy lifestyle was associated with a lower risk of colorectal cancer, while not adhering to a healthy lifestyle was associated with an increased risk of colorectal cancer.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Oncology
Konstantinos K. Tsilidis, Margarita Cariolou, Nerea Becerra-Tomas, Katia Balducci, Rita Vieira, Leila Abar, Dagfinn Aune, Georgios Markozannes, Neesha Nanu, Darren C. Greenwood, Edward L. Giovannucci, Marc J. Gunter, Alan A. Jackson, Ellen Kampman, Vivien Lund, Kate Allen, Nigel T. Brockton, Helen Croker, Daphne Katsikioti, Deirdre McGinley-Gieser, Panagiota Mitrou, Martin Wiseman, Amanda J. Cross, Elio Riboli, Steven K. Clinton, Anne McTiernan, Teresa Norat, Doris S. M. Chan
Summary: Based on systematic reviews and meta-analyses, this study found a strong association between postdiagnosis body fatness and higher all-cause mortality, breast cancer-specific mortality, and second primary breast cancer. Limited evidence suggests a relationship between body fatness and breast cancer recurrence and nonbreast cancer-related mortality. Limited-suggestive evidence indicates a lower risk of all-cause mortality and breast cancer-specific mortality with recreational physical activity. Data on dietary factors is limited. The study emphasizes the importance of lifestyle recommendations to avoid obesity and engage in physical activity for breast cancer patients.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Review
Oncology
Margarita Cariolou, Leila Abar, Dagfinn Aune, Katia Balducci, Nerea Becerra-Tomas, Darren C. Greenwood, Georgios Markozannes, Neesha Nanu, Rita Vieira, Edward L. Giovannucci, Marc J. Gunter, Alan A. Jackson, Ellen Kampman, Vivien Lund, Kate Allen, Nigel T. Brockton, Helen Croker, Daphne Katsikioti, Deirdre McGinley-Gieser, Panagiota Mitrou, Martin Wiseman, Amanda J. Cross, Elio Riboli, Steven K. Clinton, Anne McTiernan, Teresa Norat, Konstantinos K. Tsilidis, Doris S. M. Chan
Summary: This study conducted a systematic review and meta-analyses to examine the associations between physical activity and breast cancer prognosis. The results showed that moderate physical activity was associated with lower all-cause and breast cancer-specific mortality, but had no significant effect on breast cancer recurrence. Furthermore, the study found that the benefits of physical activity plateaued after reaching a certain level.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Review
Oncology
Nerea Becerra-Tomas, Katia Balducci, Leila Abar, Dagfinn Aune, Margarita Cariolou, Darren C. Greenwood, Georgios Markozannes, Neesha Nanu, Rita Vieira, Edward L. Giovannucci, Marc J. Gunter, Alan A. Jackson, Ellen Kampman, Vivien Lund, Kate Allen, Nigel T. Brockton, Helen Croker, Daphne Katsikioti, Deirdre McGinley-Gieser, Panagiota Mitrou, Martin Wiseman, Amanda J. Cross, Elio Riboli, Steven K. Clinton, Anne McTiernan, Teresa Norat, Konstantinos K. Tsilidis, Doris S. M. Chan
Summary: Little is known about the impact of diet on breast cancer prognosis. Systematic reviews and meta-analyses were conducted to summarize the evidence on postdiagnosis dietary factors and breast cancer outcomes from randomized controlled trials and observational studies. A total of 108 publications were identified, and the results generally showed limited or no significant associations between diet and breast cancer outcomes, except for some suggestive evidence related to dietary patterns, isoflavone intake, dietary fiber intake, and serum 25-hydroxyvitamin D levels.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Endocrinology & Metabolism
James Yarmolinsky, Emmanouil Bouras, Andrei Constantinescu, Kimberley Burrows, Caroline J. Bull, Emma E. Vincent, Richard M. Martin, Olympia Dimopoulou, Sarah J. Lewis, Victor Moreno, Marijana Vujkovic, Kyong-Mi Chang, Benjamin F. Voight, Philip S. Tsao, Marc J. Gunter, Jochen Hampe, Andrew J. Pellatt, Paul D. P. Pharoah, Robert E. Schoen, Steven Gallinger, Mark A. Jenkins, Rish K. Pai, Dipender Gill Bullet, Kostas K. Tsilidis
Summary: Epidemiological studies have conflicting findings on the relationship between glucose-lowering medication use and cancer risk. This study used genetic analysis to investigate the effect of pharmacological perturbation on cancer risk and found no consistent evidence to support an association between glucose-lowering drug targets and breast, colorectal, prostate, or overall cancer risk.
Article
Public, Environmental & Occupational Health
Catalina Bonet, Marta Crous-Bou, Konstantinos K. Tsilidis, Marc J. Gunter., Rudolf Kaaks., Matthias. B. Schulze, Renee T. Fortner, Christian S. Antoniussen, Christina C. Dahm, Lene Mellemkjaer, Anne Tjonneland, Pilar Amiano, Eva Ardanaz, Sandra M. Colorado-Yohar, Miguel Rodriguez-Barranco, Sandar Tin Tin, Claudia Agnoli, Giovanna Masala, Salvatore Panico, Carlotta Sacerdote, Anne M. May, Kristin Benjaminsen Borch, Charlotta Rylander, Guri Skeie, Sofia Christakoudi, Dagfinn Aune, Elisabete Weiderpass, Laure Dossus, Elio Riboli, Antonio Agudo
Summary: The study aimed to assess the association between body fatness and weight changes and overall mortality and BC-specific mortality among BC survivors. The results showed that excess body fatness is linked to poorer survival in women with BC, and substantial weight changes postdiagnosis may contribute to poorer survival.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Abhijit Sen, Katalin Gemes, Christer Svensen, Torunn Varmdal, Magnus Jonsson, Imre Janszky, Jette Moller
Summary: This large population-based register study from Norway and Sweden suggests that outpatient procedures are generally safe with regard to the postoperative risk of acute myocardial infarction (AMI). However, certain procedures such as gastrointestinal endoscopy, vascular procedures, and urological/gynaecological procedures may increase the risk of AMI by twofold or threefold within the first 8 days after the procedures. Further research is needed to assess whether this effect is influenced by cardiovascular medication or other clinical factors.
Review
Nutrition & Dietetics
Bradley W. W. Bolling, Dagfinn Aune, Hwayoung Noh, Kristina S. S. Petersen, Heinz Freisling
Summary: Dried fruits and nuts have anticarcinogenic, anti-inflammatory, and antioxidant properties due to their high nutrient and phytochemical content. Studies have shown that dried fruit consumption is inversely related to cancer risk, while increased nut intake is associated with a reduced risk of specific cancers such as colon, lung, and pancreatic cancer. Nut consumption is also linked to a decreased cancer mortality rate and improved survival outcomes for patients with colorectal, breast, and prostate cancer.
Article
Nutrition & Dietetics
Jens W. Horn, Tingting Feng, Bjorn Morkedal, Dagfinn Aune, Linn Beate Strand, Julie Horn, Kenneth J. Mukamal, Imre Janszky
Summary: This study found that BMI over adulthood is associated with the risk of ischemic stroke. Participants with overweight and obesity had a higher risk compared to normal weight participants. Early obesity and long-term weight reduction may decrease the occurrence of ischemic stroke.
Article
Multidisciplinary Sciences
Ganeshkumar Parasuaraman, Lavanya Ayyasamy, Dagfinn Aune, Abhijit Sen, Ramya Nagarajan, Prabhu Rajkumar, Saravanakumar Velusamy, P. Manickam, Satish Sivaprakasam
Summary: Studies have shown a clear association between obesity and increased risk of adult asthma, as evidenced by the summary relative risks (RR) per increase in BMI, waist circumference, and weight gain. The findings indicate a dose-response relationship, highlighting the importance of addressing overweight and obesity to reduce asthma risk. These results provide strong evidence to support policies aimed at curbing the global epidemic of overweight and obesity.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Sanju Bhattarai, Archana Shrestha, Eva Skovlund, Bjorn Olav asvold, Bente Prytz Mjolstad, Abhijit Sen
Summary: Despite effective approaches for hypertension management, many people with hypertension in Nepal remain undetected and untreated. A comprehensive intervention that includes personalised counselling, medication adherence support, and regular monitoring of blood pressure is expected to achieve well controlled blood pressure.
Article
Health Care Sciences & Services
Theresia Mina, Yik Weng Yew, Hong Kiat Ng, Nilanjana Sadhu, Gervais Wansaicheong, Rinkoo Dalan, Dorrain Yan Wen Low, Benjamin Chih Chiang Lam, Elio Riboli, Eng Sing Lee, Joanne Ngeow, Paul Elliott, Konstadina Griva, Marie Loh, Jimmy Lee, John Chambers
Summary: This study investigated the impact of adiposity and metabolic risk on cognitive function in Asian populations using both epidemiological analysis and Mendelian Randomization. The results showed that visceral fat and low HDL cholesterol levels were closely associated with cognitive decline. These findings have important implications for preserving cognitive health in the Asia-Pacific region.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2023)
Article
Endocrinology & Metabolism
Yik Weng Yew, Theresia Mina, Hong Kiat Ng, Benjamin Chih Chiang Lam, Elio Riboli, Eng Sing Lee, Jimmy Lee, Joanne Ngeow, Paul Elliott, Steven Tien Guan Thng, John C. Chambers, Marie Loh
Summary: This study aims to establish the association between obesity and skin physiology measurements and investigates whether obesity may play a possible causal role on skin barrier dysfunction. The results show a strong association between BMI and TEWL and skin pH, with suggestive evidence of a possible causal relationship. It highlights the potential impact of obesity on skin barrier function and the opportunity for prevention.
INTERNATIONAL JOURNAL OF OBESITY
(2023)
Article
Oncology
Elisabetta Casalone, Giovanni Birolo, Barbara Pardini, Alessandra Allione, Alessia Russo, Chiara Catalano, Manlio Mencoboni, Daniela Ferrante, Corrado Magnani, Marika Sculco, Irma Dianzani, Federica Grosso, Dario Mirabelli, Rosa Angela Filiberti, Ottavio Rena, Carlotta Sacerdote, Miguel Rodriguez-Barranco, Karl Smith-Byrne, Salvatore Panico, Claudia Agnoli, Theron Johnson, Rudolf Kaaks, Rosario Tumino, Jose Maria Huerta, Elio Riboli, Alicia K. Heath, Camino Trobajo-Sanmartin, Matthias B. Schulze, Calogero Saieva, Pilar Amiano, Antonio Agudo, Elisabete Weiderpass, Paolo Vineis, Giuseppe Matullo
Summary: This study identified a miRNA signature in preclinical MPM patients, which can be detected up to five years before diagnosis, providing potential non-invasive markers for early detection and intervention.
Article
Respiratory System
Sofia Christakoudi, Konstantinos K. Tsilidis, Evangelos Evangelou, Elio Riboli
Summary: In men, platelet count is positively associated with lung cancer risk, while platelet size is inversely associated, with these associations being affected by obesity. In women, only platelet count is positively associated with lung cancer risk, with little evidence of interaction with obesity.
RESPIRATORY RESEARCH
(2023)
